Aliases for JOSD1 Gene
External Ids for JOSD1 Gene
Previous GeneCards Identifiers for JOSD1 Gene
GeneCards Summary for JOSD1 Gene
JOSD1 (Josephin Domain Containing 1) is a Protein Coding gene. Among its related pathways are Josephin domain DUBs and Deubiquitination. Gene Ontology (GO) annotations related to this gene include omega peptidase activity. An important paralog of this gene is JOSD2.
UniProtKB/Swiss-Prot Summary for JOSD1 Gene
Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.