Aliases for JCHAIN Gene
External Ids for JCHAIN Gene
Previous HGNC Symbols for JCHAIN Gene
GeneCards Summary for JCHAIN Gene
JCHAIN (Joining Chain Of Multimeric IgA And IgM) is a Protein Coding gene. Diseases associated with JCHAIN include Alpha Chain Disease and Mu Chain Disease. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Cell surface interactions at the vascular wall. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and antigen binding.
UniProtKB/Swiss-Prot for JCHAIN Gene
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.