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JAML (Junction Adhesion Molecule Like) is a Protein Coding gene. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is SCN4B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005178 | integrin binding | IPI | 12869515 |
GO:0042803 | protein homodimerization activity | IDA | 12869515 |
GO:0050839 | cell adhesion molecule binding | IPI | 12869515 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0005923 | bicellular tight junction | IDA | 15800062 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0030054 | cell junction | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007155 | cell adhesion | IEA | -- |
GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | IMP | 18948633 |
GO:0030593 | neutrophil chemotaxis | IMP | 15800062 |
GO:0035696 | monocyte extravasation | IMP | 18948633 |
GO:0046629 | gamma-delta T cell activation | IEA,ISS | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | AMICA1 33 32 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | AMICA1 33 32 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | AMICA1 33 32 |
|
OneToOne | |
rat (Rattus norvegicus) |
Mammalia | Amica1 32 |
|
||
mouse (Mus musculus) |
Mammalia | Amica1 33 32 |
|
OneToOne | |
Jaml 17 |
|
||||
chicken (Gallus gallus) |
Aves | AMICA1 33 |
|
OneToOne |
SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000033150 | -- | 118,213,787(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000104794 | -- | 118,214,136(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000145497 | -- | 118,221,245(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
rs1000352345 | -- | 118,217,503(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000390697 | -- | 118,220,607(-) | C/T | genic_upstream_transcript_variant, intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3579923 | CNV | loss | 25503493 |
esv3627867 | CNV | loss | 21293372 |
nsv511 | CNV | insertion | 18451855 |
nsv952742 | CNV | duplication | 24416366 |
No disorders were found for JAML Gene.