Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associate... See more...
Aliases for ITPKC Gene
Aliases for ITPKC Gene
External Ids for ITPKC Gene
- HGNC: 14897
- NCBI Entrez Gene: 80271
- Ensembl: ENSG00000086544
- OMIM®: 606476
- UniProtKB/Swiss-Prot: Q96DU7
Previous GeneCards Identifiers for ITPKC Gene
- GC19P041862
- GC19P041614
- GC19P045899
- GC19P045914
- GC19P041223
- GC19P037656
Summaries for ITPKC Gene
-
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.[provided by RefSeq, Sep 2009]
GeneCards Summary for ITPKC Gene
ITPKC (Inositol-Trisphosphate 3-Kinase C) is a Protein Coding gene. Diseases associated with ITPKC include Kawasaki Disease and Coronary Aneurysm. Among its related pathways are superpathway of inositol phosphate compounds and Metabolism. Gene Ontology (GO) annotations related to this gene include calmodulin binding and inositol-1,4,5-trisphosphate 3-kinase activity. An important paralog of this gene is ITPKB.
UniProtKB/Swiss-Prot Summary for ITPKC Gene
-
Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
Additional gene information for ITPKC Gene
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ITPKC Gene
Genomics for ITPKC Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ITPKC Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ITPKC on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ITPKC
- Top Transcription factor binding sites by QIAGEN in the ITPKC gene promoter:
-
- c-Myb
- COUP
- COUP-TF
- COUP-TF1
- HNF-4alpha1
- HNF-4alpha2
- Lmo2
- NF-1
- SRF
Genomic Locations for ITPKC Gene
Latest Assembly
- chr19:40,717,112-40,740,860
- (GRCh38/hg38)
- Size:
- 23,749 bases
- Orientation:
- Plus strand
Previous Assembly
- chr19:41,223,017-41,246,765
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 23,749 bases
- Orientation:
- Plus strand
Genomic View for ITPKC Gene
Genes around ITPKC on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by HGNC
- 19q13.2 by Entrez Gene
- 19q13.2 by Ensembl
ITPKC Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ITPKC Gene
Proteins for ITPKC Gene
-
Protein details for ITPKC Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96DU7-IP3KC_HUMAN
- Recommended name:
- Inositol-trisphosphate 3-kinase C
- Protein Accession:
- Q96DU7
- Q9UE25
- Q9Y475
Protein attributes for ITPKC Gene
- Size:
- 683 amino acids
- Molecular mass:
- 75207 Da
- Quaternary structure:
- No Data Available
Protein Expression for ITPKC Gene
Selected DME Specific Peptides for ITPKC Gene
- Q96DU7:
-
- EGNREDGYL
- AKVWMIDFGKT
- TLGFRIEGIKK
Post-translational modifications for ITPKC Gene
Other Protein References for ITPKC Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotagā¢ IP3KC Antibody
-
Custom Antibody ServicesOriGene Antibodies for ITPKC
- Novus Biologicals Antibodies for ITPKC
- Invitrogen Antibodies for ITPKC (AFLGC-ITPKC)
-
Custom Antibody ServicesProSci Antibodies for ITPKC
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for ITPKC
- Origene Custom Protein Services for ITPKC
- antibodies-online: Show 6 available ITPKC Proteins ranked by validation data
- Compare Top ITPKC Proteins
-
Quality Products:
-
Abcam proteins for ITPKC
Assay products for research
-
Boster Bio ELISA Kits for ITPKC
Domains & Families for ITPKC Gene
Gene Families for ITPKC Gene
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Disease related genes
- Enzymes
- Potential drug targets
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for ITPKC Gene
- GenScript: Design optimal peptide antigens:
-
- Inositol 1,4,5-trisphosphate 3-kinase C (IP3KC_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96DU7- Family:
-
- Belongs to the inositol phosphokinase (IPK) family.
Function for ITPKC Gene
Molecular function for ITPKC Gene
- UniProtKB/Swiss-Prot Function:
- Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+); Xref=Rhea:RHEA:11020, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57895, ChEBI:CHEBI:203600, ChEBI:CHEBI:456216; EC=2.7.1.127;.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Activated by calcium/calmodulin. Inhibited by high concentrations of the substrate Ins(1,2,4)P3, and allosterically activated by the product Ins(1,3,4,5)P4.
- GENATLAS Biochemistry:
- inositol,1,4,5-triphosphate 3 kinase-C
Enzyme Numbers (IUBMB) for ITPKC Gene
Phenotypes From GWAS Catalog for ITPKC Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0000828 | inositol hexakisphosphate kinase activity | IBA | 21873635 |
| GO:0005516 | calmodulin binding | IEA | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity | IEA | -- |
Phenotypes for ITPKC Gene
- MGI mutant phenotypes for ITPKC:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ITPKC:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Resistant to vaccinia virus (VACV-A4L) infection
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Decreased Salmonella proliferation
- Decreased viability
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Paclitaxel antagonistic effect
- Synthetic lethal with gemcitabine
- Decreased viability in colon lineage; decreased viability in esophageal squamous lineage
Animal Models for ITPKC Gene
- MGI Knock Outs for ITPKC:
-
- Itpkc Itpkc<tm1Ssch>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ITPKC - Starting at $85 >
- * ITPKC CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ITPKC
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ITPKC
-
Santa Cruz Biotechnology (SCBT) CRISPR for ITPKC
miRNA for ITPKC Gene
- miRTarBase miRNAs that target ITPKC
-
- hsa-miR-23a-3p (MIRT050413)
- hsa-miR-4446-5p (MIRT649605)
- hsa-miR-5006-3p (MIRT649606)
- hsa-miR-4755-5p (MIRT649607)
- hsa-miR-670-5p (MIRT649608)
- hsa-miR-668-5p (MIRT649609)
- hsa-miR-642b-3p (MIRT649610)
- hsa-miR-642a-3p (MIRT649611)
- hsa-miR-6719-3p (MIRT649612)
- hsa-miR-4526 (MIRT649613)
- hsa-miR-6730-3p (MIRT649614)
- hsa-miR-3660 (MIRT649615)
- hsa-miR-301b-5p (MIRT649616)
- hsa-miR-301a-5p (MIRT649617)
- hsa-miR-6752-3p (MIRT649618)
- hsa-miR-4738-5p (MIRT649619)
- hsa-miR-500b-3p (MIRT649620)
- hsa-miR-362-3p (MIRT649621)
- hsa-miR-329-3p (MIRT649622)
- hsa-miR-8485 (MIRT649623)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ITPKC
- Browse OriGene Inhibitory RNA Products For ITPKC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ITPKC
Clone products for research
- Applied Biological Materials (abm): Clones for ITPKC - Starting at $45 >
- * ITPKC as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ITPKC
- Addgene plasmids for ITPKC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ITPKC
Cell Lines for research
-
Horizon Cell Lines for ITPKC
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ITPKC Gene
Localization for ITPKC Gene
Subcellular locations from UniProtKB/Swiss-Prot for ITPKC Gene
- Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 4 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
- Nuclear speckles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0016607 | nuclear speck | IDA | -- |
Pathways & Interactions for ITPKC Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | superpathway of inositol phosphate compounds | ||
| 2 | Metabolism |
.40
|
|
| 3 | Inositol phosphate metabolism | ||
| 4 | Calcium signaling pathway | ||
| 5 | Integrated Breast Cancer Pathway | ||
Pathways by source for ITPKC Gene
5 BioSystems pathways for ITPKC Gene
3 Reactome pathways for ITPKC Gene
4 KEGG pathways for ITPKC Gene
Interacting Proteins for ITPKC Gene
GPS-Prot Interaction Network for ITPKC
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016310 | phosphorylation | IEA | -- |
| GO:0032958 | inositol phosphate biosynthetic process | IEA,IBA | 21873635 |
| GO:0043647 | inositol phosphate metabolic process | TAS | -- |
| GO:0046854 | phosphatidylinositol phosphorylation | IBA | 21873635 |
No data available for SIGNOR curated interactions for ITPKC Gene
Drugs & Compounds for ITPKC Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
58-64-0 |
|
|||
| myo-Inositol 1,3,4,5-tetrakisphosphate |
|
99610-76-1 |
|
Transcripts for ITPKC Gene
mRNA/cDNA for ITPKC Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000263370 3376 nts (view in UCSC)
- ENST00000597003 582 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ITPKC - Starting at $85 >
- * ITPKC CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ITPKC
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ITPKC
-
Santa Cruz Biotechnology (SCBT) CRISPR for ITPKC
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ITPKC
- Browse OriGene Inhibitory RNA Products For ITPKC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ITPKC
Clone products for research
- Applied Biological Materials (abm): Clones for ITPKC - Starting at $45 >
- * ITPKC as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ITPKC
- Addgene plasmids for ITPKC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ITPKC
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | - |
Relevant External Links for ITPKC Gene
- GeneLoc Exon Structure for
- ITPKC
Expression for ITPKC Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Esophagus (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for ITPKC Gene
This gene is overexpressed in Esophagus - Mucosa (x4.4).
This gene is overexpressed in Cervix (63.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ITPKC Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ITPKC
SOURCE GeneReport for Unigene cluster for ITPKC Gene:
Hs.515415mRNA Expression by UniProt/SwissProt for ITPKC Gene:
Q96DU7-IP3KC_HUMAN
Tissue specificity:
Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
Evidence on tissue expression from TISSUES for ITPKC Gene
- Liver(4.2)
- Thyroid gland(4.1)
- Nervous system(2.5)
- Heart(2.1)
Primer products for research
-
OriGene qPCR primer pairs for ITPKC
-
OriGene qPCR primer pairs and template standards for ITPKC
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ITPKC Gene
Orthologs for ITPKC Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ITPKC 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ITPKC 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ITPKC 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Itpkc 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Itpkc 29 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ITPKC 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ITPKC 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ITPKC 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | itpkc 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | itpkca 30 |
|
OneToMany | |
| itpkcb 30 |
|
OneToMany | |||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3890 29 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | IP3K1 31 |
|
|
|
| IP3K2 30 31 |
|
OneToMany | |||
| Worm (Caenorhabditis elegans) |
Secernentea | lfe-2 30 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToMany |
- Species where no ortholog for ITPKC was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ITPKC Gene
- ENSEMBL:
- Gene Tree for ITPKC (if available)
- TreeFam:
- Gene Tree for ITPKC (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ITPKC: view image
- Alliance of Genome Resources:
- Additional Orthologs for ITPKC
Paralogs for ITPKC Gene
Variants for ITPKC Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ITPKC Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs28493229 | Risk Factor: Kawasaki disease, susceptibility to | 40,718,299(+) |
G/C NM_025194.3(ITPKC):c.1155+9G>C |
INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1067017 | CNV | gain | 25217958 |
| nsv1160619 | CNV | deletion | 26073780 |
Residual Variation Intolerance Score:
71.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.27;
52.90% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ITPKC Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ITPKC Gene
Disorders for ITPKC Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| kawasaki disease |
|
|
| coronary aneurysm |
|
|
| heart aneurysm |
|
|
| hydrops of gallbladder |
|
|
| bacterial conjunctivitis |
|
|
Search ITPKC in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ITPKC
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ITPKC Gene
Publications for ITPKC Gene
- Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C. (PMID: 11085927) Dewaste V ā¦ Erneux C (The Biochemical journal 2000) 2 3 4 22
- ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. (PMID: 18084290) Onouchi Y ā¦ Hata A (Nature genetics 2008) 3 22 72
- Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. (PMID: 22081228) Khor CC ā¦ Blue Mountains Eye Study (Nature genetics 2011) 3 40
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE ā¦ Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 40
- ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children. (PMID: 20045869) Chi H ā¦ Lee YJ (Human molecular genetics 2010) 3 40
ExternalLinks
Products for ITPKC Gene
- Custom Antibody ServicesOriGene Antibodies for ITPKC
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for ITPKC
- Origene Custom Protein Services for ITPKC
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ITPKC
- Browse OriGene Inhibitory RNA Products For ITPKC
- OriGene qPCR primer pairs for ITPKC
- OriGene qPCR primer pairs and template standards for ITPKC
- OriGene CRISPR knockouts for ITPKC
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ITPKC
- Sino Biological Human cDNA Clone for ITPKC
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ITPKC
- Novus Biologicals proteins and lysates for ITPKC
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for ITPKC
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for ITPKC (AFLGC-ITPKC)
- VectorBuilder Custom and pre-made DNA vectors for ITPKC (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ITPKC (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ITPKC (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ITPKC CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ITPKC
- Addgene plasmids for ITPKC
- antibodies-online: Show 19 available ITPKC Antibodies ranked by validation data
- Compare Top ITPKC Antibodies
- antibodies-online: Search results for available ITPKC related products ranked by validation data
- antibodies-online: Show 6 available ITPKC Proteins ranked by validation data
- Compare Top ITPKC Proteins
- Quality Products:
- Horizon Cell Lines for ITPKC
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ITPKC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ITPKC
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ITPKC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ITPKC
Sources for ITPKC Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64)