Aliases for ITPKB Gene
External Ids for ITPKB Gene
Previous GeneCards Identifiers for ITPKB Gene
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]
GeneCards Summary for ITPKB Gene
ITPKB (Inositol-Trisphosphate 3-Kinase B) is a Protein Coding gene. Diseases associated with ITPKB include Maxillary Cancer and Jaw Cancer. Among its related pathways are superpathway of inositol phosphate compounds and Metabolism. Gene Ontology (GO) annotations related to this gene include calmodulin binding and inositol-1,4,5-trisphosphate 3-kinase activity. An important paralog of this gene is ITPKC.