This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in seve... See more...

Aliases for ITGA2 Gene

Aliases for ITGA2 Gene

  • Integrin Subunit Alpha 2 2 3 5
  • Integrin, Alpha 2 (CD49B, Alpha 2 Subunit Of VLA-2 Receptor) 2 3
  • Alpha 2 Subunit Of VLA-2 Receptor 2 3
  • CD49 Antigen-Like Family Member B 3 4
  • Platelet Membrane Glycoprotein Ia 3 4
  • Collagen Receptor 3 4
  • Integrin Alpha-2 3 4
  • CD49B 3 4
  • GPIa 3 4
  • Very Late Activation Protein 2 Receptor, Alpha-2 Subunit 3
  • Human Platelet Alloantigen System 5 3
  • Platelet Glycoprotein GPIa 3
  • Platelet Antigen Br 3
  • VLA-2 Subunit Alpha 4
  • CD49b Antigen 4
  • HPA-5 3
  • VLA-2 3
  • VLAA2 3
  • ITGA2 5
  • CD49b 2
  • BR 3

External Ids for ITGA2 Gene

Previous HGNC Symbols for ITGA2 Gene

  • CD49B

Previous GeneCards Identifiers for ITGA2 Gene

  • GC05P052449
  • GC05P053715
  • GC05P052255
  • GC05P052301
  • GC05P052321
  • GC05P049257

Summaries for ITGA2 Gene

Entrez Gene Summary for ITGA2 Gene

  • This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

GeneCards Summary for ITGA2 Gene

ITGA2 (Integrin Subunit Alpha 2) is a Protein Coding gene. Diseases associated with ITGA2 include Fetal And Neonatal Alloimmune Thrombocytopenia and Bleeding Disorder, Platelet-Type, 9. Among its related pathways are Integrin Pathway and Interleukin-11 Signaling Pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and integrin binding. An important paralog of this gene is ITGA1.

UniProtKB/Swiss-Prot Summary for ITGA2 Gene

  • Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
  • (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.
  • (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.

Gene Wiki entry for ITGA2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ITGA2 Gene

Genomics for ITGA2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ITGA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ITGA2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ITGA2

Top Transcription factor binding sites by QIAGEN in the ITGA2 gene promoter:
  • FOXF2
  • Nkx2-5
  • POU2F1
  • POU2F1a
  • Sox5
  • YY1

Genomic Locations for ITGA2 Gene

Genomic Locations for ITGA2 Gene
chr5:52,989,340-53,094,779
(GRCh38/hg38)
Size:
105,440 bases
Orientation:
Plus strand
chr5:52,285,156-52,390,609
(GRCh37/hg19)
Size:
105,454 bases
Orientation:
Plus strand

Genomic View for ITGA2 Gene

Genes around ITGA2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ITGA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ITGA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ITGA2 Gene

Proteins for ITGA2 Gene

  • Protein details for ITGA2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17301-ITA2_HUMAN
    Recommended name:
    Integrin alpha-2
    Protein Accession:
    P17301
    Secondary Accessions:
    • Q14595

    Protein attributes for ITGA2 Gene

    Size:
    1181 amino acids
    Molecular mass:
    129295 Da
    Quaternary structure:
    • Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21.
    • (Microbial infection) Integrin ITGA2:ITGB1 interacts (via ITAG2 I-domain) with rotavirus A VP4 protein.
    • (Microbial infection) Integrin ITGA2:ITGB1 interacts with human echoviruses 1 and 8 capsid proteins.

    Three dimensional structures from OCA and Proteopedia for ITGA2 Gene

neXtProt entry for ITGA2 Gene

Post-translational modifications for ITGA2 Gene

  • Glycosylation at Asn105, Asn112, Asn343, Asn432, Asn460, Asn475, Asn699, Asn1057, Asn1074, and Asn1081
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect

Other Protein References for ITGA2 Gene

Antibody Products

No data available for DME Specific Peptides for ITGA2 Gene

Domains & Families for ITGA2 Gene

Gene Families for ITGA2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • CD markers
  • Plasma proteins
  • Predicted membrane proteins

Protein Domains for ITGA2 Gene

InterPro:
Blocks:
  • Von Willebrand factor type A domain signature
  • Integrins alpha chain
  • Integrin alpha chain, C-terminal cytoplasmic region
  • FG-GAP
ProtoNet:

Suggested Antigen Peptide Sequences for ITGA2 Gene

GenScript: Design optimal peptide antigens:
  • Platelet glycoprotein Ia (F1C627_HUMAN)
  • Platelet glycoprotein Ia (F1C628_HUMAN)
  • Platelet glycoprotein Ia (F1C629_HUMAN)
  • VLA-2 subunit alpha (ITA2_HUMAN)
  • GPIa protein (Q16183_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P17301

UniProtKB/Swiss-Prot:

ITA2_HUMAN :
  • The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Belongs to the integrin alpha chain family.
Domain:
  • The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Family:
  • Belongs to the integrin alpha chain family.
genes like me logo Genes that share domains with ITGA2: view

Function for ITGA2 Gene

Molecular function for ITGA2 Gene

UniProtKB/Swiss-Prot Function:
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
UniProtKB/Swiss-Prot Function:
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.
UniProtKB/Swiss-Prot Function:
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
GENATLAS Biochemistry:
integrin,alpha 2,cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or to other cells,through hetero dimerization and connecting to the cytoskeleton and various signaling molecules within cells,component of VLA-2 receptor,dimerizing with ITGB1 in collagen,laminin receptors

Phenotypes From GWAS Catalog for ITGA2 Gene

Gene Ontology (GO) - Molecular Function for ITGA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001540 amyloid-beta binding IEA,ISS --
GO:0001618 virus receptor activity IEA --
GO:0005178 integrin binding IEA --
GO:0005515 protein binding IPI 7639691
GO:0005518 collagen binding IEA,IMP 11518510
genes like me logo Genes that share ontologies with ITGA2: view
genes like me logo Genes that share phenotypes with ITGA2: view

Human Phenotype Ontology for ITGA2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ITGA2 Gene

MGI Knock Outs for ITGA2:

Animal Model Products

CRISPR Products

miRNA for ITGA2 Gene

miRTarBase miRNAs that target ITGA2

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ITGA2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ITGA2 Gene

Localization for ITGA2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ITGA2 Gene

Membrane. Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ITGA2 gene
Compartment Confidence
plasma membrane 5
extracellular 3
nucleus 3
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
endosome 2
cytosol 2
lysosome 2
peroxisome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ITGA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005886 plasma membrane IEA,TAS --
GO:0005925 focal adhesion IEA,IDA 11518510
GO:0008305 integrin complex IEA,TAS 2545729
GO:0009897 external side of plasma membrane IEA --
genes like me logo Genes that share ontologies with ITGA2: view

Pathways & Interactions for ITGA2 Gene

PathCards logo

SuperPathways for ITGA2 Gene

SuperPathway Contained pathways
1 MET promotes cell motility
2 Apoptotic Pathways in Synovial Fibroblasts
.66
.65
.64
.62
.57
3 Integrin Pathway
.67
.67
.56
.56
.38
4 Focal Adhesion
.33
5 Actin Nucleation by ARP-WASP Complex
.66
.66
.41
.35
genes like me logo Genes that share pathways with ITGA2: view

Pathways by source for ITGA2 Gene

5 GeneGo (Thomson Reuters) pathways for ITGA2 Gene
  • Cell adhesion Integrin inside-out signaling
  • Cell adhesion Integrin-mediated cell adhesion and migration
  • Cell adhesion_Endothelial cell contacts by non-junctional mechanisms
  • Cytoskeleton remodeling FAK signaling
  • Cytoskeleton remodeling Integrin outside-in signaling
33 Qiagen pathways for ITGA2 Gene
  • Actin Nucleation and Branching
  • Actin Nucleation by ARP-WASP Complex
  • Actin-Based Motility by Rho Family GTPases
  • Akt Signaling
  • Calpain Protease Regulates Cellular Mechanics

SIGNOR curated interactions for ITGA2 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for ITGA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001666 response to hypoxia IEA --
GO:0002687 positive regulation of leukocyte migration IEA --
GO:0006929 substrate-dependent cell migration IMP 11518510
GO:0006971 hypotonic response IEA --
GO:0007155 cell adhesion IEA,TAS 10201960
genes like me logo Genes that share ontologies with ITGA2: view

Drugs & Compounds for ITGA2 Gene

(22) Drugs for ITGA2 Gene - From: PharmGKB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Aspirin Approved, Vet_approved Pharma Channel blocker 1512
Clopidogrel Approved Pharma P2Y12 receptor antagonist 934

(48) Additional Compounds for ITGA2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with ITGA2: view

Transcripts for ITGA2 Gene

mRNA/cDNA for ITGA2 Gene

1 REFSEQ mRNAs :
22 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ITGA2

Alternative Splicing Database (ASD) splice patterns (SP) for ITGA2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^
SP1:
SP2: - -

ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30
SP1:
SP2:

Relevant External Links for ITGA2 Gene

GeneLoc Exon Structure for
ITGA2

Expression for ITGA2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ITGA2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ITGA2 Gene

This gene is overexpressed in Minor Salivary Gland (x4.4).

Protein differential expression in normal tissues from HIPED for ITGA2 Gene

This gene is overexpressed in Nasal epithelium (25.0) and Peripheral blood mononuclear cells (12.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ITGA2 Gene



Protein tissue co-expression partners for ITGA2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ITGA2

SOURCE GeneReport for Unigene cluster for ITGA2 Gene:

Hs.482077

Evidence on tissue expression from TISSUES for ITGA2 Gene

  • Blood(4.7)
  • Heart(4.6)
  • Liver(4.5)
  • Nervous system(3.2)
  • Spleen(3)
  • Intestine(2.8)
  • Skin(2.8)
  • Kidney(2.8)
  • Bone marrow(2.7)
  • Lung(2.6)
  • Eye(2.4)
  • Lymph node(2.4)
  • Pancreas(2.4)
  • Muscle(2.3)
  • Adrenal gland(2.3)
  • Bone(2.2)
  • Stomach(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for ITGA2 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • cardiovascular
  • integumentary
Regions:
General:
  • blood
  • coagulation system
  • skin
genes like me logo Genes that share expression patterns with ITGA2: view

No data available for mRNA Expression by UniProt/SwissProt for ITGA2 Gene

Orthologs for ITGA2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ITGA2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ITGA2 30 31
  • 99.55 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ITGA2 30 31
  • 88.61 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ITGA2 30 31
  • 88.15 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Itga2 30
  • 83.25 (n)
Mouse
(Mus musculus)
Mammalia Itga2 30 17 31
  • 83.08 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia ITGA2 31
  • 77 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia ITGA2 31
  • 77 (a)
OneToOne
Chicken
(Gallus gallus)
Aves ITGA2 30 31
  • 70.59 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia ITGA2 31
  • 65 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia itga2 30
  • 63.5 (n)
Str.15525 30
African clawed frog
(Xenopus laevis)
Amphibia itga2-A 30
Zebrafish
(Danio rerio)
Actinopterygii itga2.2 30 31
  • 57.17 (n)
OneToMany
ITGA2 (2 of 2) 31
  • 45 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 23 (a)
OneToMany
Species where no ortholog for ITGA2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ITGA2 Gene

ENSEMBL:
Gene Tree for ITGA2 (if available)
TreeFam:
Gene Tree for ITGA2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ITGA2: view image

Paralogs for ITGA2 Gene

(12) SIMAP similar genes for ITGA2 Gene using alignment to 13 proteins:

  • ITA2_HUMAN
  • D6R9H3_HUMAN
  • D6RG08_HUMAN
  • E7EMF1_HUMAN
  • E7ESP4_HUMAN
  • E9PB77_HUMAN
  • F1C627_HUMAN
  • F1C628_HUMAN
  • F1C629_HUMAN
  • G3LGR5_HUMAN
  • L0R6I3_HUMAN
  • Q71V33_HUMAN
  • Q9NNZ2_HUMAN
genes like me logo Genes that share paralogs with ITGA2: view

Variants for ITGA2 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for ITGA2 Gene

ITA2_HUMAN-P17301
Position 534 is associated with platelet-specific alloantigen HPA-5 (Br). HPA-5B/Br(a) has Lys-534 and HPA-5A/Br(b) has Glu-534. HPA-5B is involved in neonatal alloimmune thrombocytopenia (NAIT or NATP). The Lys-534-Glu polymorphism may play a role in coronary artery disease (CAD).

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ITGA2 Gene

SNP ID Clinical significance and condition Chr 05 pos Variation AA Info Type
724604 Likely Benign: not provided 53,060,002(+) T/C NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
729318 Benign: Platelet-type bleeding disorder 9; not provided 53,042,194(+) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
738496 Likely Benign: not provided 53,074,396(+) A/G NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
739011 Likely Benign: not provided 53,067,111(+) C/A INTRON_VARIANT
802121 Benign: Platelet-type bleeding disorder 9 53,071,876(+) T/C INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for ITGA2 Gene

Structural Variations from Database of Genomic Variants (DGV) for ITGA2 Gene

Variant ID Type Subtype PubMed ID
dgv9785n54 CNV loss 21841781
nsv462187 CNV gain 19166990
nsv471013 CNV gain 18288195
nsv473229 CNV novel sequence insertion 20440878
nsv598163 CNV gain 21841781
nsv598166 CNV loss 21841781
nsv598167 CNV loss 21841781
nsv598168 CNV loss 21841781
nsv598169 CNV loss 21841781
nsv598170 CNV loss 21841781
nsv830296 CNV gain 17160897

Variation tolerance for ITGA2 Gene

Residual Variation Intolerance Score: 29.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.78; 79.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ITGA2 Gene

Human Gene Mutation Database (HGMD)
ITGA2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ITGA2

SNP Genotyping and Copy Number Assay Products

Disorders for ITGA2 Gene

MalaCards: The human disease database

(28) MalaCards diseases for ITGA2 Gene - From: Orphanet, DISEASES, Novoseek, and GeneCards

Genatlas disease for ITGA2 Gene

neonatal alloimmune thrombocytopenia

Additional Disease Information for ITGA2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with ITGA2: view

No data available for UniProtKB/Swiss-Prot for ITGA2 Gene

Publications for ITGA2 Gene

  1. [Association of the integrin gene polymorphisms with ischemic stroke and plasma lipid levels]. (PMID: 19350519) Wei YS … Xie HY (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2009) 3 23 41
  2. Genetics of platelet reactivity in normal, healthy individuals. (PMID: 19740098) Kunicki TJ … Nugent DJ (Journal of thrombosis and haemostasis : JTH 2009) 3 23 41
  3. Factor VII -323 decanucleotide D/I polymorphism in atrial fibrillation: implications for the prothrombotic state and stroke risk. (PMID: 18608122) Roldán V … Vicente V (Annals of medicine 2008) 3 23 41
  4. Role of glycoprotein Ia gene polymorphisms in determining platelet function in myocardial infarction patients undergoing percutaneous coronary intervention on dual antiplatelet treatment. (PMID: 17157856) Giusti B … Abbate R (Atherosclerosis 2008) 3 23 41
  5. Platelet glycoprotein Ia 807C/T and 873G/A polymorphisms in patients with venous thromboembolism. (PMID: 17164499) Okumus G … Issever H (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2007) 3 23 41

Products for ITGA2 Gene

  • Addgene plasmids for ITGA2

Sources for ITGA2 Gene