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ISY1 (ISY1 Splicing Factor Homolog) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Transcription-Coupled Nucleotide Excision Repair (TC-NER). An important paralog of this gene is ISY1-RAB43.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003723 | RNA binding | HDA | 22658674 |
GO:0005515 | protein binding | IPI | 22365833 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000974 | Prp19 complex | IBA | 21873635 |
GO:0005634 | nucleus | IEA,IDA | 29301961 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0005681 | spliceosomal complex | IEA | -- |
GO:0071006 | U2-type catalytic step 1 spliceosome | IDA | 29301961 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | ||
2 | mRNA Splicing - Major Pathway |
.79
|
.47
|
3 | DNA Double-Strand Break Repair |
.53
|
|
4 | Gene Expression |
.48
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000350 | generation of catalytic spliceosome for second transesterification step | IEA,IBA | 21873635 |
GO:0000389 | mRNA 3'-splice site recognition | IBA | 21873635 |
GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
GO:0006283 | transcription-coupled nucleotide-excision repair | TAS | -- |
GO:0006397 | mRNA processing | IEA | -- |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ISY1 30 |
|
||
Dog (Canis familiaris) |
Mammalia | ISY1 31 |
|
OneToMany | |
Mouse (Mus musculus) |
Mammalia | Isy1 31 |
|
OneToMany | |
Cow (Bos Taurus) |
Mammalia | ISY1 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
African clawed frog (Xenopus laevis) |
Amphibia | Xl.19464 30 |
|
||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | MGC76019 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | rab43 31 |
|
OneToMany | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG9667 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | F53B7.3 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ISY1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.2201 30 |
|
No disorders were found for ISY1 Gene.