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ISLR2 (Immunoglobulin Superfamily Containing Leucine Rich Repeat 2) is a Protein Coding gene. An important paralog of this gene is ISLR.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IEA,IPI | 32296183 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0009986 | cell surface | IBA,ISS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007275 | multicellular organism development | IEA | -- |
GO:0007399 | nervous system development | IEA | -- |
GO:0045773 | positive regulation of axon extension | IBA,ISS | -- |
ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||
SP2: | - | - | - | - | |||||||||||||||||||||||||||
SP3: | - | - | - | ||||||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||||
SP5: | - | ||||||||||||||||||||||||||||||
SP6: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ISLR2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ISLR2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ISLR2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Islr2 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | LOC100910729 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
Chicken (Gallus gallus) |
Aves | ISLR2 30 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | islr2 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | islr2 30 31 |
|
OneToMany | |
Fruit Fly (Drosophila melanogaster) |
Insecta | kek4 31 |
|
ManyToMany | |
kek3 31 |
|
ManyToMany | |||
kek5 31 |
|
ManyToMany | |||
kek2 31 |
|
ManyToMany | |||
kek1 31 |
|
ManyToMany | |||
kek6 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
CSA.1672 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 15 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1567164285 | Uncertain Significance: not provided | 74,134,413(+) |
CT/C NM_020851.3(ISLR2):c.1660del (p.Trp554fs) |
FRAMESHIFT | |
rs3889598 | - |
p.Ser137Phe |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2760040 | CNV | gain+loss | 17122850 |
nsv1047564 | CNV | gain | 25217958 |
nsv1050884 | CNV | gain | 25217958 |
nsv1121512 | CNV | deletion | 24896259 |
nsv428308 | CNV | gain+loss | 18775914 |
nsv469619 | CNV | loss | 16826518 |
nsv827385 | CNV | gain | 20364138 |
nsv833053 | CNV | loss | 17160897 |
nsv951993 | CNV | deletion | 24416366 |
No disorders were found for ISLR2 Gene.