Aliases for ISG20L2 Gene
External Ids for ISG20L2 Gene
Previous GeneCards Identifiers for ISG20L2 Gene
This gene encodes a 3'-5' exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014]
GeneCards Summary for ISG20L2 Gene
ISG20L2 (Interferon Stimulated Exonuclease Gene 20 Like 2) is a Protein Coding gene. Diseases associated with ISG20L2 include Inflammatory Bowel Disease 3 and Bladder Carcinoma In Situ. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and exonuclease activity. An important paralog of this gene is AEN.
UniProtKB/Swiss-Prot Summary for ISG20L2 Gene
3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group.