Aliases for ISG20 Gene
External Ids for ISG20 Gene
Previous GeneCards Identifiers for ISG20 Gene
GeneCards Summary for ISG20 Gene
ISG20 (Interferon Stimulated Exonuclease Gene 20) is a Protein Coding gene. Diseases associated with ISG20 include Hepatitis C and Viral Infectious Disease. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and 3-5-exoribonuclease activity. An important paralog of this gene is AEN.
UniProtKB/Swiss-Prot for ISG20 Gene
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.