Aliases for IRF2BP1 Gene
External Ids for IRF2BP1 Gene
Previous GeneCards Identifiers for IRF2BP1 Gene
GeneCards Summary for IRF2BP1 Gene
IRF2BP1 (Interferon Regulatory Factor 2 Binding Protein 1) is a Protein Coding gene. Diseases associated with IRF2BP1 include Cecal Disease. Gene Ontology (GO) annotations related to this gene include ligase activity. An important paralog of this gene is IRF2BPL.
UniProtKB/Swiss-Prot Summary for IRF2BP1 Gene
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.