Aliases for IRAG2 Gene
External Ids for IRAG2 Gene
Previous HGNC Symbols for IRAG2 Gene
The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
GeneCards Summary for IRAG2 Gene
IRAG2 (Inositol 1,4,5-Triphosphate Receptor Associated 2) is a Protein Coding gene. Diseases associated with IRAG2 include Respiratory System Benign Neoplasm and Lung Adenoma. Among its related pathways are Innate Immune System. An important paralog of this gene is IRAG1.
UniProtKB/Swiss-Prot Summary for IRAG2 Gene
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules.