Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IQCN Gene

Aliases for IQCN Gene

  • IQ Motif Containing N 2 3
  • KIAA1683 2 3 4 5
  • Uncharacterized Protein KIAA1683 3
  • IQ Domain-Containing Protein N 3

External Ids for IQCN Gene

Previous HGNC Symbols for IQCN Gene

  • KIAA1683

Summaries for IQCN Gene

GeneCards Summary for IQCN Gene

IQCN (IQ Motif Containing N) is a Protein Coding gene.

Gene Wiki entry for IQCN Gene

Additional gene information for IQCN Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCN Gene

Genomics for IQCN Gene

GeneHancer (GH) Regulatory Elements for IQCN Gene

Promoters and enhancers for IQCN Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I018273 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 571.3 -0.7 -668 2.8 PKNOX1 SMAD1 MLX ARID4B SIN3A YY1 POLR2B FOS MXD4 REST IQCN PDE4C PIR55689
GH19I018272 Enhancer 0.7 ENCODE 550.8 +2.0 1963 0.2 CTCF MAX ZNF384 RAD21 ZEB1 ZNF444 ZNF600 ATF7 ZNF362 ZNF654 IQCN SUGP2 PIR52469
GH19I018270 Promoter 0.5 EPDnew 550.8 +4.4 4439 0.1 IQCN PIR52469
GH19I017336 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 83.9 +937.2 937153 2.5 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 SP3 GTPBP3 CHERP ENSG00000269578 ENSG00000268743 IQCN COLGALT1 C19orf44 SIN3B HAUS8 MVB12A
GH19I018274 Enhancer 0.3 ENCODE 568.3 +1.0 953 0.1 CHD7 IQCN PIR52469
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IQCN on UCSC Golden Path with GeneCards custom track

Genomic Locations for IQCN Gene

Genomic Locations for IQCN Gene
17,414 bases
Minus strand

Genomic View for IQCN Gene

Genes around IQCN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCN Gene

Proteins for IQCN Gene

  • Protein details for IQCN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein N
    Protein Accession:
    Secondary Accessions:
    • B4DYH2
    • E9PDE0
    • E9PH54
    • Q2KHR5
    • Q8N4G8
    • Q96M14
    • Q9C0I0

    Protein attributes for IQCN Gene

    1180 amino acids
    Molecular mass:
    127693 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB21774.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};

    Alternative splice isoforms for IQCN Gene


neXtProt entry for IQCN Gene

Post-translational modifications for IQCN Gene

No Post-translational modifications

No data available for DME Specific Peptides for IQCN Gene

Domains & Families for IQCN Gene

Gene Families for IQCN Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for IQCN Gene

Suggested Antigen Peptide Sequences for IQCN Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IQCN: view

No data available for UniProtKB/Swiss-Prot for IQCN Gene

Function for IQCN Gene

Phenotypes From GWAS Catalog for IQCN Gene

Gene Ontology (GO) - Molecular Function for IQCN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with IQCN: view

Phenotypes for IQCN Gene

genes like me logo Genes that share phenotypes with IQCN: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCN Gene

Localization for IQCN Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IQCN gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytosol 3
plasma membrane 1
extracellular 1
peroxisome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for IQCN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,HDA 21630459
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with IQCN: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for IQCN Gene

Pathways & Interactions for IQCN Gene

No Data Available

Gene Ontology (GO) - Biological Process for IQCN Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCN Gene

Drugs & Compounds for IQCN Gene

No Compound Related Data Available

Transcripts for IQCN Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IQCN Gene

No ASD Table

Relevant External Links for IQCN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCN Gene

NURSA nuclear receptor signaling pathways regulating expression of IQCN Gene:


Evidence on tissue expression from TISSUES for IQCN Gene

  • Nervous system(4.1)
  • Skin(4)
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IQCN Gene

Orthologs for IQCN Gene

This gene was present in the common ancestor of mammals.

Orthologs for IQCN Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KIAA1683 34 33
  • 97.95 (n)
(Canis familiaris)
Mammalia KIAA1683 34 33
  • 70.94 (n)
(Bos Taurus)
Mammalia KIAA1683 34 33
  • 70.02 (n)
(Ornithorhynchus anatinus)
Mammalia KIAA1683 34
  • 23 (a)
(Monodelphis domestica)
Mammalia KIAA1683 34
  • 13 (a)
Species where no ortholog for IQCN was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCN Gene

Gene Tree for IQCN (if available)
Gene Tree for IQCN (if available)

Paralogs for IQCN Gene

No data available for Paralogs for IQCN Gene

Variants for IQCN Gene

Sequence variations from dbSNP and Humsavar for IQCN Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000128963 -- 18,266,342(-) T/C coding_sequence_variant, missense_variant
rs1000253499 -- 18,275,362(-) T/C upstream_transcript_variant
rs1000717083 -- 18,268,683(-) G/T intron_variant
rs1000940649 -- 18,260,160(-) A/G intron_variant
rs1001194309 -- 18,274,126(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for IQCN Gene

Variant ID Type Subtype PubMed ID
nsv952420 CNV deletion 24416366
nsv833775 CNV loss 17160897
nsv828472 CNV loss 20364138
nsv578744 CNV gain 21841781
nsv470131 CNV loss 18288195
nsv1115541 CNV duplication 24896259
esv2718287 CNV deletion 23290073

Variation tolerance for IQCN Gene

Residual Variation Intolerance Score: 99.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.03; 87.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IQCN Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCN Gene

Disorders for IQCN Gene

Additional Disease Information for IQCN

No disorders were found for IQCN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCN Gene

Publications for IQCN Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 58
  2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for IQCN Gene

Sources for IQCN Gene

Loading form....