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Aliases for IQCF6 Gene

Aliases for IQCF6 Gene

  • IQ Motif Containing F6 2 3 5

External Ids for IQCF6 Gene

Summaries for IQCF6 Gene

GeneCards Summary for IQCF6 Gene

IQCF6 (IQ Motif Containing F6) is a Protein Coding gene. An important paralog of this gene is IQCF5.

Additional gene information for IQCF6 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF6 Gene

Genomics for IQCF6 Gene

GeneHancer (GH) Regulatory Elements for IQCF6 Gene

Promoters and enhancers for IQCF6 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I051779 Promoter 0.6 EPDnew 550.8 +0.5 516 0.1 ZNF133 GC03M051764 IQCF6 LOC105377087
GH03I052243 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.9 -466.1 -466113 4.9 HDGF PKNOX1 SIN3A IRF4 ZNF48 YY1 GLIS2 ZNF143 ATF7 FOS PPM1M PBRM1 LOC101929054 GLYCTK IQCF2 IQCF5 PHF7 IQCF6 IQCF1 WDR82
GH03I051678 Enhancer 1.3 FANTOM5 Ensembl ENCODE 12.7 +98.8 98810 4.1 HDGF HDAC1 ELF3 PKNOX1 RB1 ARID4B KLF5 RAD21 TCF12 ZNF207 IQCF6 DCAF1 RNU6ATAC29P GPR62 IQCF1 IQCF5 IQCF2 PIR41340 RNA5SP132 TEX264
GH03I051684 Enhancer 1.2 FANTOM5 Ensembl ENCODE 10.2 +93.5 93542 3.6 ETV1 TAL1 MAX EBF1 TCF12 NCOR1 POLR2A EGR1 VEZF1 SCRT2 TEX264 DCAF1 RNU6ATAC29P IQCF6 RPL29 RNA5SP132 PIR41340
GH03I052074 Enhancer 0.4 FANTOM5 28.7 -294.8 -294818 0.2 ZFP36 ZMYM3 IQCF2 PHF7 IQCF5 IQCF1 IQCF6 LINC00696 POC1A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IQCF6 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the IQCF6 gene promoter:

Genomic Locations for IQCF6 Gene

Genomic Locations for IQCF6 Gene
1,213 bases
Minus strand

Genomic View for IQCF6 Gene

Genes around IQCF6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCF6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCF6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF6 Gene

Proteins for IQCF6 Gene

  • Protein details for IQCF6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein F6
    Protein Accession:

    Protein attributes for IQCF6 Gene

    107 amino acids
    Molecular mass:
    13059 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF6 Gene

Post-translational modifications for IQCF6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCF6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCF6 Gene

Domains & Families for IQCF6 Gene

Gene Families for IQCF6 Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for IQCF6 Gene


Suggested Antigen Peptide Sequences for IQCF6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IQCF6: view

No data available for UniProtKB/Swiss-Prot for IQCF6 Gene

Function for IQCF6 Gene

Phenotypes From GWAS Catalog for IQCF6 Gene

Gene Ontology (GO) - Molecular Function for IQCF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005516 calmodulin binding IBA --
genes like me logo Genes that share ontologies with IQCF6: view

Phenotypes for IQCF6 Gene

GenomeRNAi human phenotypes for IQCF6:
genes like me logo Genes that share phenotypes with IQCF6: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF6 Gene

Localization for IQCF6 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IQCF6 gene
Compartment Confidence
mitochondrion 2
cytosol 2
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IQCF6 Gene

Pathways & Interactions for IQCF6 Gene

SuperPathways for IQCF6 Gene

No Data Available

Interacting Proteins for IQCF6 Gene

Gene Ontology (GO) - Biological Process for IQCF6 Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCF6 Gene

Drugs & Compounds for IQCF6 Gene

No Compound Related Data Available

Transcripts for IQCF6 Gene

mRNA/cDNA for IQCF6 Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCF6 Gene

IQ motif containing F6:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF6 Gene

No ASD Table

Relevant External Links for IQCF6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCF6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IQCF6 Gene

mRNA differential expression in normal tissues according to GTEx for IQCF6 Gene

This gene is overexpressed in Testis (x51.7).

NURSA nuclear receptor signaling pathways regulating expression of IQCF6 Gene:


SOURCE GeneReport for Unigene cluster for IQCF6 Gene:

genes like me logo Genes that share expression patterns with IQCF6: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IQCF6 Gene

Orthologs for IQCF6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF6 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia IQCF6 33 34
  • 98.75 (n)
(Canis familiaris)
Mammalia IQCF6 33 34
  • 95.28 (n)
(Bos Taurus)
Mammalia IQCF6 33 34
  • 95.02 (n)
(Mus musculus)
Mammalia Iqcf6 33 16 34
  • 86.92 (n)
(Rattus norvegicus)
Mammalia Iqcf6 33
  • 83.49 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 46 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 21 (a)
Species where no ortholog for IQCF6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF6 Gene

Gene Tree for IQCF6 (if available)
Gene Tree for IQCF6 (if available)

Paralogs for IQCF6 Gene

Paralogs for IQCF6 Gene

(4) SIMAP similar genes for IQCF6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with IQCF6: view

Variants for IQCF6 Gene

Sequence variations from dbSNP and Humsavar for IQCF6 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1001241308 -- 51,780,032(-) G/A upstream_transcript_variant
rs1001460599 -- 51,780,154(-) C/T upstream_transcript_variant
rs1002468022 -- 51,779,042(-) C/A/T intron_variant
rs1002597987 -- 51,778,440(-) G/A downstream_transcript_variant
rs1003603513 -- 51,779,828(-) TTTTTTTTTTT/TTTTTTTTTTTT upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for IQCF6 Gene

Variant ID Type Subtype PubMed ID
nsv508921 CNV insertion 20534489
nsv520211 CNV gain 19592680

Variation tolerance for IQCF6 Gene

Gene Damage Index Score: 8.02; 84.23% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IQCF6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF6 Gene

Disorders for IQCF6 Gene

Additional Disease Information for IQCF6

No disorders were found for IQCF6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF6 Gene

Publications for IQCF6 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58

Products for IQCF6 Gene

Sources for IQCF6 Gene

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