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Aliases for IQCF5 Gene

Aliases for IQCF5 Gene

  • IQ Motif Containing F5 2 3 5

External Ids for IQCF5 Gene

Previous GeneCards Identifiers for IQCF5 Gene

  • GC03M051883
  • GC03M051884

Summaries for IQCF5 Gene

GeneCards Summary for IQCF5 Gene

IQCF5 (IQ Motif Containing F5) is a Protein Coding gene. An important paralog of this gene is IQCF1.

Additional gene information for IQCF5 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF5 Gene

Genomics for IQCF5 Gene

GeneHancer (GH) Regulatory Elements for IQCF5 Gene

Promoters and enhancers for IQCF5 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I051875 Promoter 0.5 EPDnew 550.8 0.0 -37 0.1 IQCF5 IQCF5-AS1 IQCF1 GC03P051793
GH03I052243 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 14.5 -370.3 -370302 4.9 HDGF PKNOX1 SIN3A IRF4 ZNF48 YY1 GLIS2 ZNF143 ATF7 FOS PPM1M PBRM1 LOC101929054 GLYCTK IQCF2 IQCF5 PHF7 IQCF6 IQCF1 WDR82
GH03I052074 Enhancer 0.4 FANTOM5 31.2 -199.0 -199007 0.2 ZFP36 ZMYM3 IQCF2 PHF7 IQCF5 IQCF1 IQCF6 LINC00696 POC1A
GH03I051902 Enhancer 0.6 ENCODE 11.8 -27.0 -26976 0.2 ZNF639 KLF1 SP3 INSM2 ZNF223 KLF17 TSHZ1 JUND ZNF629 FOS IQCF1 IQCF5 IQCF5-AS1 RN7SL504P IQCF3 IQCF4 GPR62 PCBP4 IQCF2
GH03I051903 Promoter 0.6 EPDnew 11.8 -27.8 -27789 0.1 CREB1 IQCF1 IQCF5 IQCF5-AS1 RN7SL504P IQCF3 IQCF4 GPR62 PCBP4 RRP9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IQCF5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the IQCF5 gene promoter:

Genomic Locations for IQCF5 Gene

Genomic Locations for IQCF5 Gene
1,864 bases
Minus strand

Genomic View for IQCF5 Gene

Genes around IQCF5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCF5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCF5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF5 Gene

Proteins for IQCF5 Gene

  • Protein details for IQCF5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein F5
    Protein Accession:

    Protein attributes for IQCF5 Gene

    148 amino acids
    Molecular mass:
    18048 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF5 Gene

Post-translational modifications for IQCF5 Gene

No Post-translational modifications

Other Protein References for IQCF5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCF5 Gene

Domains & Families for IQCF5 Gene

Gene Families for IQCF5 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for IQCF5 Gene


Suggested Antigen Peptide Sequences for IQCF5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IQCF5: view

No data available for UniProtKB/Swiss-Prot for IQCF5 Gene

Function for IQCF5 Gene

Phenotypes From GWAS Catalog for IQCF5 Gene

Gene Ontology (GO) - Molecular Function for IQCF5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005516 calmodulin binding IBA --
genes like me logo Genes that share ontologies with IQCF5: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF5 Gene

Localization for IQCF5 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IQCF5 gene
Compartment Confidence
extracellular 2
cytosol 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IQCF5 Gene

Pathways & Interactions for IQCF5 Gene

SuperPathways for IQCF5 Gene

No Data Available

Interacting Proteins for IQCF5 Gene

Gene Ontology (GO) - Biological Process for IQCF5 Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCF5 Gene

Drugs & Compounds for IQCF5 Gene

No Compound Related Data Available

Transcripts for IQCF5 Gene

mRNA/cDNA for IQCF5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCF5 Gene

IQ motif containing F5:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF5 Gene

No ASD Table

Relevant External Links for IQCF5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCF5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IQCF5 Gene

mRNA differential expression in normal tissues according to GTEx for IQCF5 Gene

This gene is overexpressed in Testis (x52.9).

NURSA nuclear receptor signaling pathways regulating expression of IQCF5 Gene:


SOURCE GeneReport for Unigene cluster for IQCF5 Gene:

genes like me logo Genes that share expression patterns with IQCF5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IQCF5 Gene

Orthologs for IQCF5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia IQCF5 33 34
  • 99.1 (n)
(Canis familiaris)
Mammalia IQCF5 33 34
  • 79.14 (n)
(Rattus norvegicus)
Mammalia Iqcf5 33
  • 77.93 (n)
(Bos Taurus)
Mammalia IQCF5 33 34
  • 77.7 (n)
(Mus musculus)
Mammalia Iqcf5 33 16 34
  • 77.48 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 39 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 28 (a)
Species where no ortholog for IQCF5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF5 Gene

Gene Tree for IQCF5 (if available)
Gene Tree for IQCF5 (if available)

Paralogs for IQCF5 Gene

Paralogs for IQCF5 Gene

(4) SIMAP similar genes for IQCF5 Gene using alignment to 1 proteins: Pseudogenes for IQCF5 Gene

genes like me logo Genes that share paralogs with IQCF5: view

Variants for IQCF5 Gene

Sequence variations from dbSNP and Humsavar for IQCF5 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1001039892 -- 51,876,690(-) G/A upstream_transcript_variant
rs1001210895 -- 51,873,303(-) T/C downstream_transcript_variant
rs1002923600 -- 51,874,066(-) A/G coding_sequence_variant, synonymous_variant
rs1002978122 -- 51,874,601(-) T/C intron_variant
rs1004426610 -- 51,874,114(-) C/A coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for IQCF5 Gene

Variant ID Type Subtype PubMed ID
nsv3817 CNV insertion 18451855
nsv520211 CNV gain 19592680

Variation tolerance for IQCF5 Gene

Gene Damage Index Score: 1.79; 33.79% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IQCF5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF5 Gene

Disorders for IQCF5 Gene

Additional Disease Information for IQCF5

No disorders were found for IQCF5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF5 Gene

Publications for IQCF5 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 3 4 58
  2. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T … Xu R (Neurobiology of aging 2014) 3 58

Products for IQCF5 Gene

Sources for IQCF5 Gene

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