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The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] See more...
Aliases for IPP Gene
Aliases for IPP Gene
External Ids for IPP Gene
- HGNC: 6108
- Entrez Gene: 3652
- Ensembl: ENSG00000197429
- OMIM: 147485
- UniProtKB: Q9Y573
Previous GeneCards Identifiers for IPP Gene
- GC01M045891
- GC01M045164
- GC01M045594
- GC01M045577
- GC01M045829
- GC01M046159
- GC01M044271
Summaries for IPP Gene
-
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for IPP Gene
IPP (Intracisternal A Particle-Promoted Polypeptide) is a Protein Coding gene. Diseases associated with IPP include Penile Disease and Peroneal Nerve Paralysis. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is KLHL20.
UniProtKB/Swiss-Prot Summary for IPP Gene
-
May play a role in organizing the actin cytoskeleton.
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IPP Gene
Genomics for IPP Gene
GeneHancer (GH) Regulatory Elements for IPP Gene
Promoters and enhancers for IPP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around IPP on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the IPP gene promoter:
-
- AML1a
- AP-1
- ATF-2
- c-Jun
- ER-alpha
- FOXC1
- POU3F1
- SREBP-1a
- SREBP-1b
- SREBP-1c
Genomic Locations for IPP Gene
Genomic Locations for IPP Gene
- chr1:45,694,324-45,750,813
- (GRCh38/hg38)
- Size:
- 56,490 bases
- Orientation:
- Minus strand
- chr1:46,159,996-46,216,485
- (GRCh37/hg19)
- Size:
- 56,490 bases
- Orientation:
- Minus strand
Genomic View for IPP Gene
Genes around IPP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.1 by HGNC
- 1p34.1 by Entrez Gene
- 1p34.1 by Ensembl
IPP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IPP Gene
Proteins for IPP Gene
-
Protein details for IPP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y573-IPP_HUMAN
- Recommended name:
- Actin-binding protein IPP
- Protein Accession:
- Q9Y573
- A2A6V4
- D3DQ11
- Q8N5C3
Protein attributes for IPP Gene
- Size:
- 584 amino acids
- Molecular mass:
- 65261 Da
- Quaternary structure:
- No Data Available
Protein Expression for IPP Gene
Post-translational modifications for IPP Gene
Other Protein References for IPP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Biolabs Mouse Anti-ITGA6 Recombinant Antibody (4C1)
-
Custom Antibody ServicesOriGene Antibodies for IPP
- Novus Biologicals Antibodies for IPP
-
Abcam antibodies for IPP
- Invitrogen Antibodies for IPP (AFLGC-IPP)
-
Biorbyt antibodies for IPP
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for IPP
- Origene Custom Protein Services for IPP
- Novus Biologicals proteins for IPP
- ProSpec Recombinant Proteins for IPP
- antibodies-online: Show 4 available IPP Proteins ranked by validation data
- Compare Top IPP Proteins
-
Quality Products:
-
Abcam proteins for IPP
Assay Products
- antibodies-online: Show 4 available IPP Elisa Kits ranked by validation data
- Compare Top IPP Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for IPP Gene
Domains & Families for IPP Gene
Gene Families for IPP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for IPP Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for IPP Gene
- GenScript: Design optimal peptide antigens:
-
- Intracisternal A particle-promoted polypeptide (A2A6V3_HUMAN)
- Kelch-like protein 27 (IPP_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for IPP Gene
Function for IPP Gene
Molecular function for IPP Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in organizing the actin cytoskeleton.
- GENATLAS Biochemistry:
- intracisternal A-particle (IAP)-promoted,placenta,mouse homolog,Kelch family member
Phenotypes From GWAS Catalog for IPP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IEA | -- |
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for IPP Gene
- MGI mutant phenotypes for IPP:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IPP:
Animal Models for IPP Gene
- MGI Knock Outs for IPP:
-
- Ipp Ipp<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for IPP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IPP
- genomics-online: gRNA clones - Search for available IPP gRNA products
- Overview of 102 available IPP gene related products
- Applied Biological Materials (abm): CRISPR Clones for IPP - Select products 50% OFF >
- * IPP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * IPP CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for IPP
miRNA for IPP Gene
- miRTarBase miRNAs that target IPP
-
- hsa-mir-21-5p (MIRT030826)
- hsa-mir-222-3p (MIRT046572)
- hsa-mir-651-5p (MIRT508755)
- hsa-mir-6811-5p (MIRT508756)
- hsa-mir-6807-5p (MIRT508757)
- hsa-mir-6511b-5p (MIRT508758)
- hsa-mir-1258 (MIRT508759)
- hsa-mir-3152-3p (MIRT508760)
- hsa-mir-520h (MIRT508761)
- hsa-mir-520g-3p (MIRT508762)
- hsa-mir-3159 (MIRT508763)
- hsa-mir-4252 (MIRT515372)
- hsa-mir-150-5p (MIRT515373)
- hsa-mir-186-3p (MIRT515374)
- hsa-mir-1273g-3p (MIRT515375)
- hsa-mir-4325 (MIRT550328)
- hsa-mir-7703 (MIRT550329)
- hsa-mir-6720-5p (MIRT550330)
- hsa-mir-6512-3p (MIRT550331)
- hsa-mir-542-3p (MIRT550332)
- hsa-mir-4765 (MIRT550333)
- hsa-mir-1236-5p (MIRT550334)
- hsa-mir-766-3p (MIRT550335)
- hsa-mir-6849-3p (MIRT550336)
- hsa-mir-1228-3p (MIRT550337)
- hsa-mir-92b-3p (MIRT550338)
- hsa-mir-92a-3p (MIRT550339)
- hsa-mir-367-3p (MIRT550340)
- hsa-mir-363-3p (MIRT550341)
- hsa-mir-32-5p (MIRT550342)
- hsa-mir-25-3p (MIRT550343)
- hsa-mir-4293 (MIRT550344)
- hsa-mir-508-5p (MIRT550345)
- hsa-mir-4279 (MIRT618311)
- hsa-mir-4291 (MIRT618312)
- hsa-mir-6829-3p (MIRT618313)
- hsa-mir-6791-3p (MIRT618314)
- hsa-mir-1976 (MIRT618315)
- hsa-mir-3653-5p (MIRT618316)
- hsa-mir-6747-3p (MIRT618317)
- hsa-mir-6727-3p (MIRT618318)
- hsa-mir-4722-3p (MIRT618319)
- hsa-mir-5193 (MIRT618320)
- hsa-mir-1207-3p (MIRT618321)
- hsa-mir-761 (MIRT618322)
- hsa-mir-3619-5p (MIRT618323)
- hsa-mir-214-3p (MIRT618324)
- hsa-mir-922 (MIRT618325)
- hsa-mir-6513-3p (MIRT618326)
- hsa-mir-8062 (MIRT618327)
- hsa-mir-646 (MIRT618328)
- hsa-mir-1303 (MIRT644326)
- hsa-mir-182-5p (MIRT644327)
- hsa-mir-411-5p (MIRT644328)
- hsa-mir-193b-5p (MIRT644329)
- hsa-mir-6809-5p (MIRT644330)
- hsa-mir-31-5p (MIRT644331)
- hsa-mir-4696 (MIRT644332)
- hsa-mir-4463 (MIRT644333)
- hsa-mir-483-5p (MIRT644334)
- hsa-mir-5096 (MIRT674419)
- hsa-mir-197-3p (MIRT674420)
- hsa-mir-6832-5p (MIRT674421)
- hsa-mir-4716-5p (MIRT674422)
- hsa-mir-4781-3p (MIRT674423)
- hsa-mir-6744-3p (MIRT691598)
- hsa-mir-4757-5p (MIRT691599)
- hsa-mir-5589-5p (MIRT691600)
- hsa-mir-4731-5p (MIRT691601)
- hsa-mir-372-5p (MIRT691602)
- hsa-mir-371a-5p (MIRT691603)
- hsa-mir-616-5p (MIRT691604)
- hsa-mir-373-5p (MIRT691605)
- hsa-mir-371b-5p (MIRT691606)
- hsa-mir-7107-5p (MIRT691607)
- hsa-mir-1234-3p (MIRT691608)
- hsa-mir-6827-3p (MIRT691609)
- hsa-mir-340-3p (MIRT691610)
- hsa-mir-1306-5p (MIRT691611)
- hsa-mir-3973 (MIRT691612)
- hsa-mir-552-3p (MIRT691613)
- hsa-mir-520e (MIRT691614)
- hsa-mir-520d-3p (MIRT691615)
- hsa-mir-520c-3p (MIRT691616)
- hsa-mir-520b (MIRT691617)
- hsa-mir-520a-3p (MIRT691618)
- hsa-mir-373-3p (MIRT691619)
- hsa-mir-372-3p (MIRT691620)
- hsa-mir-302e (MIRT691621)
- hsa-mir-302d-3p (MIRT691622)
- hsa-mir-302c-3p (MIRT691623)
- hsa-mir-302b-3p (MIRT691624)
- hsa-mir-302a-3p (MIRT691625)
- hsa-mir-93-5p (MIRT691626)
- hsa-mir-526b-3p (MIRT691627)
- hsa-mir-519d-3p (MIRT691628)
- hsa-mir-20b-5p (MIRT691629)
- hsa-mir-20a-5p (MIRT691630)
- hsa-mir-17-5p (MIRT691631)
- hsa-mir-106b-5p (MIRT691632)
- hsa-mir-106a-5p (MIRT691633)
- hsa-mir-4310 (MIRT768543)
- hsa-mir-4740-3p (MIRT771858)
- hsa-mir-498 (MIRT772839)
- hsa-mir-7157-5p (MIRT781559)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for IPP
- Browse OriGene Inhibitory RNA Products For IPP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IPP
- genomics-online: shRNA clones - Search for available IPP shRNA products
- Overview of 102 available IPP gene related products
Clone Products
- Sino Biological Human cDNA Clone for IPP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IPP
- genomics-online: cdna clones - Search for available IPP CDNA products
- Overview of 102 available IPP gene related products
- orf clones - Search for available IPP ORF products
- Overview of 102 available IPP gene related products
- Applied Biological Materials (abm): Clones for IPP - Select products 50% OFF >
- * IPP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * IPP tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for IPP
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IPP Gene
Localization for IPP Gene
Subcellular locations from UniProtKB/Swiss-Prot for IPP Gene
- Cytoplasm, cytoskeleton.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 4 |
| plasma membrane | 2 |
| nucleus | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0015629 | actin cytoskeleton | TAS | 10072760 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IPP Gene
Pathways & Interactions for IPP Gene
Interacting Proteins for IPP Gene
GPS-Prot Interaction Network for IPP
No data available for Pathways by source and SIGNOR curated interactions for IPP Gene
Transcripts for IPP Gene
mRNA/cDNA for IPP Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (18) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000359942 1947 bps (ENST00000359942.8)
- ENST00000461718 399 bps (ENST00000461718.5)
- ENST00000495072 727 bps (ENST00000495072.1)
- ENST00000396478 3113 bps (ENST00000396478.3)
CRISPR Products
-
OriGene CRISPR knockouts for IPP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IPP
- genomics-online: gRNA clones - Search for available IPP gRNA products
- Overview of 102 available IPP gene related products
- Applied Biological Materials (abm): CRISPR Clones for IPP - Select products 50% OFF >
- * IPP CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * IPP CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for IPP
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for IPP
- Browse OriGene Inhibitory RNA Products For IPP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IPP
- genomics-online: shRNA clones - Search for available IPP shRNA products
- Overview of 102 available IPP gene related products
Clone Products
- Sino Biological Human cDNA Clone for IPP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IPP
- genomics-online: cdna clones - Search for available IPP CDNA products
- Overview of 102 available IPP gene related products
- orf clones - Search for available IPP ORF products
- Overview of 102 available IPP gene related products
- Applied Biological Materials (abm): Clones for IPP - Select products 50% OFF >
- * IPP as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * IPP tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for IPP Gene
This gene is overexpressed in Heart (50.1) and Placenta (18.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for IPP Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of IPP Gene:
IPPSOURCE GeneReport for Unigene cluster for IPP Gene:
Hs.744252Evidence on tissue expression from TISSUES for IPP Gene
- Thyroid gland(4.2)
- Blood(2.2)
- Nervous system(2.2)
- Intestine(2)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs for IPP
- genomics-online: primer clones - Search for available IPP Primer products
- Overview of 102 available IPP gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IPP Gene
Orthologs for IPP Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IPP 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | IPP 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | IPP 33 32 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | IPP 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ipp 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ipp 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | IPP 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | IPP 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | IPP 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ipp 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ipp 33 32 |
|
OneToOne | |
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2413 32 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG9426 33 34 32 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009913 32 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 33 |
|
OneToMany | |
| -- 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| CSA.6551 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| CSA.2774 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany | |||
| -- 33 |
|
OneToMany |
- Species where no ortholog for IPP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for IPP Gene
- ENSEMBL:
- Gene Tree for IPP (if available)
- TreeFam:
- Gene Tree for IPP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for IPP: view image
Paralogs for IPP Gene
Paralogs for IPP Gene
- KLHL20 5
- KLHL2 5
- KLHL18 5
- KLHL5 5
- KLHL17 5
- KEAP1 5
- KLHL3 5
- KLHL12 5
- KLHL1 5
- KLHL28 5
- KLHL4 5
- KLHL8 5
- KLHL26 5
- KLHL10 5
- KLHL24 5
- KLHL22 5
- KLHL36 5
- KLHL6 5
- KLHL9 5
- KLHL21 5
- KLHL23 5
- KBTBD8 5
- KLHL13 5
- KBTBD12 5
- KLHL29 5
- KLHL32 5
- KLHL34 5
- KLHL7 5
- KLHL35 5
- KLHL31 5
- GAN 5
- IVNS1ABP 5
- KLHL15 5
- KLHL30 5
- KLHL40 5
- KLHL38 5
- KBTBD7 5
- KLHL14 5
- KBTBD2 5
- KBTBD6 5
- KLHL41 5
- KBTBD3 5
- CCIN 5
- BTBD18 5
- KBTBD11 5
- KLHL33 5
- KLHL42 5
- BACH2 5
- KBTBD13 5
- GRIK1-AS2 5
- KLHDC8B 5
- KLHDC7A 5
- KLHDC8A 5
- KLHDC7B 5
- ENSG00000277971 5
(16) SIMAP similar genes for IPP Gene using alignment to 1 proteins:
- IPP_HUMAN
Variants for IPP Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000011065 | -- | 45,709,058(-) | AAAAAAAA/AAAAAAAAA | genic_downstream_transcript_variant, intron_variant | |
| rs1000013616 | -- | 45,696,316(-) | C/G/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000129756 | -- | 45,740,145(-) | T/C | intron_variant | |
| rs1000193583 | -- | 45,742,240(-) | T/G | intron_variant | |
| rs1000222642 | -- | 45,740,558(-) | C/A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv159n100 | CNV | gain | 25217958 |
| esv1007960 | CNV | insertion | 20482838 |
| esv1730955 | CNV | deletion | 17803354 |
| esv2023284 | CNV | deletion | 18987734 |
| esv2747830 | CNV | deletion | 23290073 |
| esv3561582 | CNV | deletion | 23714750 |
| esv3577360 | CNV | gain | 25503493 |
| esv3577471 | CNV | gain | 25503493 |
| esv3585914 | CNV | gain | 21293372 |
| esv3585915 | CNV | gain | 21293372 |
| esv3585916 | CNV | gain | 21293372 |
| esv3893512 | CNV | gain | 25118596 |
| esv4646 | CNV | loss | 18987735 |
| nsv1014128 | CNV | gain | 25217958 |
| nsv1113112 | CNV | deletion | 24896259 |
| nsv1149283 | CNV | deletion | 26484159 |
| nsv159558 | CNV | deletion | 16902084 |
| nsv436781 | CNV | insertion | 17901297 |
| nsv945922 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
24.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.69;
91.46% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IPP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IPP
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IPP Gene
Disorders for IPP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| penile disease |
|
|
| peroneal nerve paralysis |
|
|
Search IPP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for IPP
No data available for UniProtKB/Swiss-Prot and Genatlas for IPP Gene
Publications for IPP Gene
- The IPP gene is assigned to human chromosome 1p32-1p22. (PMID: 8432546) Chang-Yeh A … Huang RC (Genomics 1993) 2 3 4 56
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
- Isolation and characterization of IPP, a novel human gene encoding an actin-binding, kelch-like protein. (PMID: 10072760) Kim IF … Huang RC (Gene 1999) 3 4 56
- Cell lineage-specific expression of the MIPP gene. (PMID: 1905535) Mold DE … Huang RC (Biochemical and biophysical research communications 1991) 2 3 56
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 56
ExternalLinks
Products for IPP Gene
- Custom Antibody ServicesOriGene Antibodies for IPP
- Browse OriGene ELISA Kits
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- antibodies-online: Show 16 available IPP Antibodies ranked by validation data
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- antibodies-online: Show 4 available IPP Elisa Kits ranked by validation data
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- antibodies-online: Show 4 available IPP Proteins ranked by validation data
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- Horizon Cell Lines for IPP
- genomics-online: cdna clones - Search for available IPP CDNA products
- Overview of 102 available IPP gene related products
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for IPP
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- Biorbyt antibodies for IPP
Sources for IPP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
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- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
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- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
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- (156) DiseaseEnhancer
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- (158) Biorbyt
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- (160) Mastermind
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- (164) Synthego
- (165) Bio Basic
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- (168) LncBase
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- (170) LNCipedia
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- (180) MyBioSource