Aliases for INSRR Gene
External Ids for INSRR Gene
Previous GeneCards Identifiers for INSRR Gene
GeneCards Summary for INSRR Gene
INSRR (Insulin Receptor Related Receptor) is a Protein Coding gene. Diseases associated with INSRR include Uterine Corpus Sarcoma and Rickettsialpox. Among its related pathways are ERK Signaling and Nanog in Mammalian ESC Pluripotency. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is IGF1R.
UniProtKB/Swiss-Prot Summary for INSRR Gene
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.