Aliases for INSL5 Gene
External Ids for INSL5 Gene
Previous GeneCards Identifiers for INSL5 Gene
The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). [provided by RefSeq, Jul 2008]
GeneCards Summary for INSL5 Gene
INSL5 (Insulin Like 5) is a Protein Coding gene. Diseases associated with INSL5 include Fatal Infantile Hypertonic Myofibrillar Myopathy and Cryptorchidism, Unilateral Or Bilateral. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include hormone activity. An important paralog of this gene is RLN3.
UniProtKB/Swiss-Prot Summary for INSL5 Gene
May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.