Aliases for INS-IGF2 Gene
External Ids for INS-IGF2 Gene
Previous GeneCards Identifiers for INS-IGF2 Gene
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]
GeneCards Summary for INS-IGF2 Gene
INS-IGF2 (INS-IGF2 Readthrough) is a Protein Coding gene. Diseases associated with INS-IGF2 include Maturity-Onset Diabetes Of The Young, Type 10 and Diabetes Mellitus, Insulin-Dependent, 2. Among its related pathways are AMP-activated Protein Kinase (AMPK) Signaling and Type II diabetes mellitus. Gene Ontology (GO) annotations related to this gene include hormone activity. An important paralog of this gene is INS.