Aliases for INPP5J Gene
External Ids for INPP5J Gene
Previous HGNC Symbols for INPP5J Gene
Previous GeneCards Identifiers for INPP5J Gene
GeneCards Summary for INPP5J Gene
INPP5J (Inositol Polyphosphate-5-Phosphatase J) is a Protein Coding gene. Diseases associated with INPP5J include Lowe Oculocerebrorenal Syndrome. Among its related pathways are Glycerophospholipid biosynthesis and superpathway of inositol phosphate compounds. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and inositol-1,4,5-trisphosphate 5-phosphatase activity. An important paralog of this gene is INPP5K.
UniProtKB/Swiss-Prot Summary for INPP5J Gene
Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles (By similarity).