The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008] See more...

Aliases for INPP5A Gene

Aliases for INPP5A Gene

  • Inositol Polyphosphate-5-Phosphatase A 2 3 4 5
  • Type I Inositol 1,4,5-Trisphosphate 5-Phosphatase 3 4
  • Inositol Polyphosphate-5-Phosphatase, 40kDa 2 3
  • 43 KDa Inositol Polyphosphate 5-Phosphatase 3 4
  • 43 KDa Inositol Polyphosphate 5-Phophatase 2 3
  • Inositol Polyphosphate-5-Phosphatase, 40kD 2 3
  • CTCL Tumor Antigen HD-CL-02 2 3
  • InsP3 5-Phosphatase 2 3
  • 5PTASE 3 4
  • Type I Inositol-1,4,5-Trisphosphate 5-Phosphatase 2
  • Type I Inositol-1,4,5-Trisphosphate 5-Phophatase 3
  • Inositol Trisphosphate-5-Phosphatase, 40kD 3
  • Inositol Polyphosphate 5-Phophatase, 40kDa 2
  • EC 3.1.3.56 4
  • 5PTase 4

External Ids for INPP5A Gene

Previous GeneCards Identifiers for INPP5A Gene

  • GC10P133261
  • GC10P133484
  • GC10P134228
  • GC10P133786
  • GC10P133785
  • GC10P134201
  • GC10P134351
  • GC10P127903

Summaries for INPP5A Gene

Entrez Gene Summary for INPP5A Gene

  • The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]

GeneCards Summary for INPP5A Gene

INPP5A (Inositol Polyphosphate-5-Phosphatase A) is a Protein Coding gene. Diseases associated with INPP5A include Lowe Oculocerebrorenal Syndrome. Among its related pathways are superpathway of inositol phosphate compounds and Inositol phosphate metabolism. Gene Ontology (GO) annotations related to this gene include inositol-polyphosphate 5-phosphatase activity and inositol-1,4,5-trisphosphate 5-phosphatase activity.

UniProtKB/Swiss-Prot Summary for INPP5A Gene

  • Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate.

Gene Wiki entry for INPP5A Gene

Additional gene information for INPP5A Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for INPP5A Gene

Genomics for INPP5A Gene

GeneHancer (GH) Regulatory Elements for INPP5A Gene

Promoters and enhancers for INPP5A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around INPP5A on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for INPP5A

Top Transcription factor binding sites by QIAGEN in the INPP5A gene promoter:
  • AP-2gamma
  • Arnt
  • COUP
  • COUP-TF
  • COUP-TF1
  • FOXO1
  • FOXO1a
  • HNF-4alpha1
  • POU2F1
  • POU2F1a

Genomic Locations for INPP5A Gene

Genomic Locations for INPP5A Gene
chr10:132,537,784-132,783,480
(GRCh38/hg38)
Size:
245,697 bases
Orientation:
Plus strand
chr10:134,351,324-134,596,984
(GRCh37/hg19)
Size:
245,661 bases
Orientation:
Plus strand

Genomic View for INPP5A Gene

Genes around INPP5A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INPP5A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INPP5A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INPP5A Gene

Proteins for INPP5A Gene

  • Protein details for INPP5A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14642-I5P1_HUMAN
    Recommended name:
    Inositol polyphosphate-5-phosphatase A
    Protein Accession:
    Q14642
    Secondary Accessions:
    • D3DXI3
    • Q14640
    • Q5JSF1

    Protein attributes for INPP5A Gene

    Size:
    412 amino acids
    Molecular mass:
    47820 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INPP5A Gene

Post-translational modifications for INPP5A Gene

  • Ubiquitination at Lys73, Lys265, Lys284, Lys307, and Lys358
  • Modification sites at PhosphoSitePlus

Other Protein References for INPP5A Gene

No data available for DME Specific Peptides for INPP5A Gene

Domains & Families for INPP5A Gene

Gene Families for INPP5A Gene

Protein Domains for INPP5A Gene

Blocks:
  • Inositol polyphosphate related phosphatase family
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for INPP5A Gene

GenScript: Design optimal peptide antigens:
  • Inositol polyphosphate-5-phosphatase, 40kDa (B1AP38_HUMAN)
  • Type I inositol-1,4,5-trisphosphate 5-phosphatase (I5P1_HUMAN)
  • INPP5A protein (Q149S6_HUMAN)
  • INPP5A protein (Q4VAR4_HUMAN)
  • Inositol polyphosphate-5-phosphatase, 40kDa (Q5JT87_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q14642

UniProtKB/Swiss-Prot:

I5P1_HUMAN :
  • Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
Family:
  • Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
genes like me logo Genes that share domains with INPP5A: view

Function for INPP5A Gene

Molecular function for INPP5A Gene

UniProtKB/Swiss-Prot Function:
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate; Xref=Rhea:RHEA:19797, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:58282, ChEBI:CHEBI:203600; EC=3.1.3.56; Evidence=. ; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19798; Evidence=. ;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate; Xref=Rhea:RHEA:11392, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:57895, ChEBI:CHEBI:58414; EC=3.1.3.56; Evidence=. ; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:11393; Evidence=. ;.
GENATLAS Biochemistry:
inositol 1,4,5-triphosphate 5-phosphatase (43kDa) membrane-associated,predominantly expressed in heart,brain,skeletal,muscle,signal terminating reaction in the inositol signaling pathway

Enzyme Numbers (IUBMB) for INPP5A Gene

Phenotypes From GWAS Catalog for INPP5A Gene

Gene Ontology (GO) - Molecular Function for INPP5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004445 inositol-polyphosphate 5-phosphatase activity NAS 8006039
GO:0005515 protein binding IPI 8999861
GO:0016787 hydrolase activity IEA --
GO:0042731 PH domain binding IPI 8999861
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity IEA --
genes like me logo Genes that share ontologies with INPP5A: view
genes like me logo Genes that share phenotypes with INPP5A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for INPP5A

CRISPR Products

miRNA for INPP5A Gene

Clone Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for INPP5A Gene

Localization for INPP5A Gene

Subcellular locations from UniProtKB/Swiss-Prot for INPP5A Gene

Cell membrane; Lipid-anchor.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for INPP5A gene
Compartment Confidence
plasma membrane 4
cytosol 3
extracellular 2
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
lysosome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for INPP5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane NAS 8006039
genes like me logo Genes that share ontologies with INPP5A: view

Pathways & Interactions for INPP5A Gene

genes like me logo Genes that share pathways with INPP5A: view

Gene Ontology (GO) - Biological Process for INPP5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016311 dephosphorylation IEA --
GO:0043647 inositol phosphate metabolic process TAS --
GO:0046855 inositol phosphate dephosphorylation IBA 21873635
GO:0046856 phosphatidylinositol dephosphorylation IEA --
GO:0048016 inositol phosphate-mediated signaling IBA 21873635
genes like me logo Genes that share ontologies with INPP5A: view

No data available for SIGNOR curated interactions for INPP5A Gene

Drugs & Compounds for INPP5A Gene

(4) Drugs for INPP5A Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
Calcium Approved Nutra 7884
D-Myo-Inositol-1,4-Bisphosphate Experimental Pharma 0

(6) Additional Compounds for INPP5A Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Inositol 1,3,4,5-tetraphosphate
  • 1,3,4,5-Tetrakis(dihydrogen phosphate) myo-inositol
  • 1D-myo-Inositol 1,3,4,5-tetrakis(dihydrogen phosphate)
  • 1D-myo-Inositol 1,3,4,5-tetrakisphosphate
  • D-myo-Inositol 1,3,4,5-tetrakisphosphate
  • Inositol 1,3,4,5-tetrakis(phosphate)
102850-29-3
Inositol 1,3,4-trisphosphate
  • (1S,3S,4S)-1,3,4-triphospho-myo-INOSITOL
  • D-myo-Inositol 1,3,4-trisphosphate
  • Inositol 1,3,4-trisphosphoric acid
  • D-myo-Inositol 1,3,4-trisphosphoric acid
  • 1,3,4-Itp
98102-63-7
Inositol 1,4,5-trisphosphate
  • 1,4,5-Insp3
  • D-myo-Inositol 1,4,5-trisphosphate
  • D-myo-INOSITOL-1,4,5-triphosphATE
  • Ins(1,4,5)P3
  • InsP3
88269-39-0
Phosphate
  • [po(OH)3]
  • Acide phosphorique
  • Acidum phosphoricum
  • H3PO4
  • Orthophosphoric acid
14066-19-4, 14265-44-2
genes like me logo Genes that share compounds with INPP5A: view

Transcripts for INPP5A Gene

mRNA/cDNA for INPP5A Gene

2 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for INPP5A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16
SP1: -
SP2:
SP3: - - -

Relevant External Links for INPP5A Gene

GeneLoc Exon Structure for
INPP5A

Expression for INPP5A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for INPP5A Gene

Protein differential expression in normal tissues from HIPED for INPP5A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (16.9), Breast (14.3), and Frontal cortex (11.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for INPP5A Gene



Protein tissue co-expression partners for INPP5A Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for INPP5A

SOURCE GeneReport for Unigene cluster for INPP5A Gene:

Hs.523360

mRNA Expression by UniProt/SwissProt for INPP5A Gene:

Q14642-I5P1_HUMAN
Tissue specificity: Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039). In brain; high level in Purkinje cells (PubMed:8013665).

Evidence on tissue expression from TISSUES for INPP5A Gene

  • Nervous system(4.6)
genes like me logo Genes that share expression patterns with INPP5A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for INPP5A Gene

Orthologs for INPP5A Gene

This gene was present in the common ancestor of animals.

Orthologs for INPP5A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia INPP5A 31 30
  • 99.6 (n)
OneToOne
dog
(Canis familiaris)
Mammalia INPP5A 31 30
  • 90.7 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Inpp5a 17 31 30
  • 90.21 (n)
rat
(Rattus norvegicus)
Mammalia Inpp5a 30
  • 90.21 (n)
cow
(Bos Taurus)
Mammalia INPP5A 31 30
  • 87.57 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia INPP5A 31
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia INPP5A 31
  • 50 (a)
OneToOne
chicken
(Gallus gallus)
Aves INPP5A 31 30
  • 82.36 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia INPP5A 31
  • 91 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia inpp5a.1 30
  • 77.43 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8191 30
zebrafish
(Danio rerio)
Actinopterygii INPP5A 31
  • 74 (a)
OneToOne
zgc:123248 30
  • 61.27 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000203 30
  • 56.28 (n)
fruit fly
(Drosophila melanogaster)
Insecta 5PtaseI 31 30
  • 53.66 (n)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea ipp-5 31 30
  • 49.64 (n)
OneToMany
C01B10.3 31
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2673 31
  • 38 (a)
OneToOne
Species where no ortholog for INPP5A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for INPP5A Gene

ENSEMBL:
Gene Tree for INPP5A (if available)
TreeFam:
Gene Tree for INPP5A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for INPP5A: view image

Paralogs for INPP5A Gene

No data available for Paralogs for INPP5A Gene

Variants for INPP5A Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for INPP5A Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs1133400 - p.Lys45Arg

Additional dbSNP identifiers (rs#s) for INPP5A Gene

Structural Variations from Database of Genomic Variants (DGV) for INPP5A Gene

Variant ID Type Subtype PubMed ID
dgv118e201 CNV deletion 23290073
dgv119e201 CNV deletion 23290073
dgv1461n54 CNV gain 21841781
dgv183n67 CNV gain 20364138
dgv184n67 CNV gain 20364138
dgv524e59 CNV duplication 20981092
dgv525e59 CNV duplication 20981092
esv1003188 CNV deletion 20482838
esv1043694 CNV deletion 17803354
esv1197964 CNV deletion 17803354
esv1199957 CNV deletion 17803354
esv1277422 CNV deletion 17803354
esv1314079 CNV insertion 17803354
esv1420103 CNV deletion 17803354
esv1471684 CNV insertion 17803354
esv1507539 CNV deletion 17803354
esv1531275 CNV insertion 17803354
esv1579193 CNV deletion 17803354
esv1681558 CNV deletion 17803354
esv1685428 CNV insertion 17803354
esv2274837 CNV deletion 18987734
esv25225 CNV gain 19812545
esv2619584 CNV deletion 19546169
esv2657781 CNV deletion 23128226
esv2676009 CNV deletion 23128226
esv2743694 CNV deletion 23290073
esv2743695 CNV deletion 23290073
esv2743698 CNV deletion 23290073
esv2743699 CNV deletion 23290073
esv2743700 CNV deletion 23290073
esv2743701 CNV deletion 23290073
esv2743702 CNV deletion 23290073
esv2743703 CNV deletion 23290073
esv2743704 CNV deletion 23290073
esv2743705 CNV deletion 23290073
esv2743706 CNV deletion 23290073
esv2743707 CNV deletion 23290073
esv2743709 CNV deletion 23290073
esv2743710 CNV deletion 23290073
esv2743711 CNV deletion 23290073
esv2743712 CNV deletion 23290073
esv2743713 CNV deletion 23290073
esv2743714 CNV deletion 23290073
esv2743715 CNV deletion 23290073
esv2743716 CNV deletion 23290073
esv2743717 CNV deletion 23290073
esv2743718 CNV deletion 23290073
esv2743720 CNV deletion 23290073
esv2743721 CNV deletion 23290073
esv2743722 CNV deletion 23290073
esv2743723 CNV deletion 23290073
esv2743725 CNV deletion 23290073
esv2743727 CNV deletion 23290073
esv2743728 CNV deletion 23290073
esv2743729 CNV deletion 23290073
esv2759791 CNV loss 17122850
esv28015 CNV gain 19812545
esv28744 CNV loss 19812545
esv28959 CNV gain+loss 19812545
esv3332310 CNV duplication 20981092
esv3426248 CNV duplication 20981092
esv3547120 CNV deletion 23714750
esv3547124 CNV deletion 23714750
esv3547126 CNV deletion 23714750
esv3547129 CNV deletion 23714750
esv3577883 CNV gain 25503493
esv3577894 CNV gain 25503493
esv3624986 CNV gain 21293372
esv3624995 CNV gain 21293372
esv3625001 CNV gain 21293372
esv992316 CNV deletion 20482838
esv998279 CNV deletion 20482838
esv999432 CNV deletion 20482838
nsv1054934 CNV gain 25217958
nsv1069528 CNV deletion 25765185
nsv1110680 CNV insertion 24896259
nsv1113351 CNV deletion 24896259
nsv1139410 CNV deletion 24896259
nsv1146682 CNV duplication 26484159
nsv1153234 CNV deletion 26484159
nsv24773 CNV deletion 16902084
nsv24809 CNV deletion 16902084
nsv24819 CNV insertion 16902084
nsv25372 CNV deletion 16902084
nsv25414 CNV deletion 16902084
nsv25439 CNV deletion 16902084
nsv467496 CNV gain 19166990
nsv470977 CNV loss 18288195
nsv472249 CNV novel sequence insertion 20440878
nsv509376 CNV insertion 20534489
nsv509377 CNV insertion 20534489
nsv509378 CNV insertion 20534489
nsv513303 CNV insertion 21212237
nsv552523 CNV loss 21841781
nsv552525 CNV gain 21841781
nsv552526 CNV gain 21841781
nsv552527 CNV loss 21841781
nsv552528 CNV gain 21841781
nsv7628 CNV insertion 18451855
nsv820457 CNV deletion 20802225
nsv821276 CNV deletion 20802225
nsv825660 CNV gain 20364138
nsv825663 CNV gain 20364138
nsv832032 CNV loss 17160897
nsv832033 CNV loss 17160897
nsv832034 CNV loss 17160897
nsv952698 CNV deletion 24416366
nsv952700 CNV deletion 24416366

Variation tolerance for INPP5A Gene

Residual Variation Intolerance Score: 43.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.46; 82.05% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for INPP5A Gene

Human Gene Mutation Database (HGMD)
INPP5A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
INPP5A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for INPP5A Gene

Disorders for INPP5A Gene

MalaCards: The human disease database

(1) MalaCards diseases for INPP5A Gene - From: DISEASES

Disorder Aliases PubMed IDs
lowe oculocerebrorenal syndrome
  • ocrl
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for INPP5A

genes like me logo Genes that share disorders with INPP5A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for INPP5A Gene

Publications for INPP5A Gene

  1. Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells. (PMID: 8013665) De Smedt F … Erneux C (FEBS letters 1994) 2 3 4 23 54
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 54
  4. Chromosomal mapping of the gene (INPP5A) encoding the 43-kDa membrane-associated inositol polyphosphate 5-phosphatase to 10q26.3 by fluorescence in situ hybridization. (PMID: 8808294) Mitchell CA … Sutherland GR (Genomics 1996) 3 23 54
  5. Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphatase. (PMID: 8006039) Laxminarayan KM … Mitchell CA (The Journal of biological chemistry 1994) 3 4 54

Products for INPP5A Gene

Sources for INPP5A Gene