Free for academic non-profit institutions. Other users need a Commercial license
The protein encoded by this gene is a subunit of single-stranded DNA binding complexes that are important for maintaining genome stability. These complexes are involved in G2/M checkpoint control and homologous recombination repair. [provided by RefSeq, Jul 2016]
INIP (INTS3 And NABP Interacting Protein) is a Protein Coding gene.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 19683501 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 19605351 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0035861 | site of double-strand break | IDA | 19683501 |
GO:0070876 | SOSS complex | IEA,IDA | 18449195 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006281 | DNA repair | IEA,IMP | 19605351 |
GO:0006974 | cellular response to DNA damage stimulus | IEA,IMP | 19683501 |
GO:0010212 | response to ionizing radiation | IMP | 19605351 |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f | · | 6g |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||||||||||||||
SP2: | - | - | |||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | ||||||||||||||||||||||||||||||||||
SP5: | - | - | - | ||||||||||||||||||||||||||||||||||
SP6: | - | - | - | ||||||||||||||||||||||||||||||||||
SP7: | - | - | - | - |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | C9H9orf80 30 |
|
||
C9H9ORF80 31 |
|
OneToOne | |||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | INIP 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | INIP 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Inip 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Inip 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | INIP 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | CZH9ORF80 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | INIP 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | inip 30 |
|
||
Str.10998 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | hspc043-A-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | inip 30 31 |
|
OneToOne | |
zgc56259 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10677 30 |
|
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv262e55 | CNV | gain | 17911159 |
dgv7701n100 | CNV | gain | 25217958 |
esv2759710 | CNV | gain | 17122850 |
esv2761275 | CNV | gain | 21179565 |
esv3621517 | CNV | gain | 21293372 |
esv3621518 | CNV | gain | 21293372 |
nsv415734 | CNV | deletion | 16902084 |
nsv442163 | CNV | gain | 18776908 |
nsv471317 | CNV | gain | 18288195 |
nsv515121 | CNV | gain | 21397061 |
nsv515899 | CNV | gain+loss | 19592680 |
nsv615198 | CNV | gain | 21841781 |
No disorders were found for INIP Gene.