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This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in... See more...
Aliases for ING5 Gene
Aliases for ING5 Gene
External Ids for ING5 Gene
- HGNC: 19421
- NCBI Entrez Gene: 84289
- Ensembl: ENSG00000168395
- OMIM®: 608525
- UniProtKB/Swiss-Prot: Q8WYH8
Previous GeneCards Identifiers for ING5 Gene
- GC02M238853
- GC02M239540
- GC02P242661
- GC02P242962
- GC02P242361
- GC02P242291
- GC02P234396
- GC02P242641
Summaries for ING5 Gene
-
This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016]
GeneCards Summary for ING5 Gene
ING5 (Inhibitor Of Growth Family Member 5) is a Protein Coding gene. Diseases associated with ING5 include Ohdo Syndrome, Sbbys Variant and Atrophy Of Testis. Among its related pathways are Regulation of TP53 Activity through Acetylation and Chromatin organization. Gene Ontology (GO) annotations related to this gene include chromatin binding and methylated histone binding. An important paralog of this gene is ING4.
UniProtKB/Swiss-Prot Summary for ING5 Gene
-
Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4 (PubMed:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator (PubMed:12750254, PubMed:16387653). Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner (PubMed:21750715).
Additional gene information for ING5 Gene
- HGNC (19421)
- NCBI Entrez Gene (84289)
- Ensembl (ENSG00000168395)
- OMIM® (608525)
- UniProtKB/Swiss-Prot (Q8WYH8)
- Open Targets Platform(ENSG00000168395)
- Search for ING5 at DataMed
- Search for ING5 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ING5 Gene
Genomics for ING5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ING5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ING5 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ING5
- Top Transcription factor binding sites by QIAGEN in the ING5 gene promoter:
-
- AREB6
- GATA-3
- Lmo2
- NF-1
- NF-1/L
- Nkx2-5
- Nkx5-1
- Pax-4a
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for ING5 Gene
Latest Assembly
- chr2:241,687,017-241,729,481
- (GRCh38/hg38)
- Size:
- 42,465 bases
- Orientation:
- Plus strand
Previous Assembly
- chr2:242,626,435-242,668,893
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 42,459 bases
- Orientation:
- Plus strand
- chr2:242,641,450-242,668,893
- (GRCh37/hg19 by Ensembl)
- Size:
- 27,444 bases
- Orientation:
- Plus strand
Genomic View for ING5 Gene
Genes around ING5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q37.3 by HGNC
- 2q37.3 by Entrez Gene
- 2q37.3 by Ensembl
ING5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ING5 Gene
Proteins for ING5 Gene
-
Protein details for ING5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WYH8-ING5_HUMAN
- Recommended name:
- Inhibitor of growth protein 5
- Protein Accession:
- Q8WYH8
- A8K1P3
- Q53NU6
- Q57Z54
- Q9BS30
Protein attributes for ING5 Gene
- Size:
- 240 amino acids
- Molecular mass:
- 27751 Da
- Quaternary structure:
-
- Component of the HBO1 complex composed of KAT7/HBO1, MEAF6, ING5, and one scaffold subunit: complexes containing BRPF scaffold (BRPF1, BRD1/BRPF2 or BRPF3) direct KAT7/HBO1 specificity towards H3K14ac, while complexes containing JADE scaffold (JADE1, JADE2 and JADE3) mediate acetylation of histone H4 (PubMed:16387653, PubMed:24065767). Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3 (PubMed:16387653, PubMed:18794358). Interacts with H3K4me3 and to a lesser extent with H3K4me2 (PubMed:16728974, PubMed:18623064). Interacts with EP300 and p53/TP53 (PubMed:12750254). Interacts with INCA1 (PubMed:21750715).
Protein Expression for ING5 Gene
Post-translational modifications for ING5 Gene
Other Protein References for ING5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ ING5 Antibody
-
Custom Antibody ServicesOriGene Antibodies for ING5
- Novus Biologicals Antibodies for ING5
-
Abcam antibodies for ING5
- Invitrogen Antibodies for ING5 (AFLGC-ING5)
-
Custom Antibody ServicesProSci Antibodies for ING5
-
Santa Cruz Biotechnology (SCBT) Antibodies for ING5
- Sino Biological Antibodies for ING5
Protein products for research
-
OriGene Purified Proteins for ING5
- Search Origene for MassSpec and Protein Over-expression Lysates for ING5
- Origene Custom Protein Services for ING5
- Sino Biological Recombinant Proteins for ING5
- Browse Sino Biological Cell Lysates
-
Abcam proteins for ING5
Assay products for research
- antibodies-online: Search results for available ING5 related products ranked by validation data
No data available for DME Specific Peptides for ING5 Gene
Domains & Families for ING5 Gene
Gene Families for ING5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ING5 Gene
- InterPro:
- Blocks:
-
- Zn-finger-like, PHD finger
- ProtoNet:
Suggested Antigen Peptide Sequences for ING5 Gene
- GenScript: Design optimal peptide antigens:
-
- p28ING5 (ING5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WYH8UniProtKB/Swiss-Prot:
ING5_HUMAN :- The PHD-type zinc finger mediates the binding to H3K4me3.
- Belongs to the ING family.
- Domain:
-
- The PHD-type zinc finger mediates the binding to H3K4me3.
- Family:
-
- Belongs to the ING family.
Function for ING5 Gene
Molecular function for ING5 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4 (PubMed:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator (PubMed:12750254, PubMed:16387653). Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner (PubMed:21750715).
Phenotypes From GWAS Catalog for ING5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003682 | chromatin binding | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 12750254 |
| GO:0035064 | methylated histone binding | IBA,IDA | 16728974 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ING5 Gene
- MGI mutant phenotypes for ING5:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ING5:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ING5 - Starting at $85 >
- * ING5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ING5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ING5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ING5
miRNA for ING5 Gene
- miRTarBase miRNAs that target ING5
-
- rno-miR-193a-3p (MIRT054044)
- mmu-miR-150-5p (MIRT582879)
- mmu-miR-5127 (MIRT582880)
- mmu-miR-1196-5p (MIRT582881)
- mmu-miR-129-5p (MIRT594400)
- mmu-miR-3096b-5p (MIRT594401)
- mmu-miR-128-3p (MIRT598589)
- mmu-miR-665-3p (MIRT598590)
- mmu-miR-539-5p (MIRT598591)
- mmu-miR-1264-3p (MIRT598592)
- hsa-miR-7157-3p (MIRT614364)
- hsa-miR-6737-3p (MIRT614365)
- hsa-miR-5008-3p (MIRT614366)
- hsa-miR-1914-5p (MIRT614367)
- hsa-miR-8485 (MIRT614368)
- hsa-miR-649 (MIRT614369)
- hsa-miR-6515-5p (MIRT710920)
- hsa-miR-4443 (MIRT710921)
- hsa-miR-6827-5p (MIRT710922)
- hsa-miR-6797-5p (MIRT710923)
- hsa-miR-1249-5p (MIRT710924)
- hsa-miR-6133 (MIRT710925)
- hsa-miR-6130 (MIRT710926)
- hsa-miR-6129 (MIRT710927)
- hsa-miR-6127 (MIRT710928)
- hsa-miR-4510 (MIRT710929)
- hsa-miR-4419a (MIRT710930)
- hsa-miR-1225-3p (MIRT710931)
- hsa-miR-432-5p (MIRT710932)
- hsa-miR-6756-3p (MIRT710933)
- hsa-miR-3127-3p (MIRT710934)
- hsa-miR-4650-5p (MIRT710935)
- hsa-miR-1972 (MIRT710936)
- hsa-miR-6769a-3p (MIRT710937)
- hsa-miR-331-3p (MIRT731739)
- hsa-miR-193a-5p (MIRT734428)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ING5
- Browse OriGene Inhibitory RNA Products For ING5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ING5
Clone products for research
- Applied Biological Materials (abm): Clones for ING5 - Starting at $45 >
- * ING5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ING5
- Addgene plasmids for ING5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ING5
Cell Lines for research
-
Horizon Cell Lines for ING5
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ING5 Gene
Localization for ING5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ING5 Gene
- Nucleus. Chromosome. Note=Localizes to transcription start sites. {ECO:0000269 PubMed:24065767}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytosol | 2 |
| golgi apparatus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000123 | histone acetyltransferase complex | IDA | 24065767 |
| GO:0005634 | nucleus | IEA,IDA | 18794358 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0070776 | MOZ/MORF histone acetyltransferase complex | IEA,IDA | 16387653 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ING5 Gene
Pathways & Interactions for ING5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin organization | ||
| 2 | Gene Expression |
.48
|
|
| 3 | Regulation of TP53 Activity | ||
| 4 | Regulation of TP53 Activity through Acetylation | ||
Pathways by source for ING5 Gene
8 Reactome pathways for ING5 Gene
Interacting Proteins for ING5 Gene
Selected Interacting proteins:
Q8WYH8-ING5_HUMAN
ENSP00000322142
for ING5 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for ING5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006260 | DNA replication | IDA | 16387653 |
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0006473 | protein acetylation | IDA | 12750254 |
| GO:0008285 | negative regulation of cell proliferation | IEA,IGI | 21750715 |
| GO:0016573 | histone acetylation | IEA | -- |
No data available for SIGNOR curated interactions for ING5 Gene
Transcripts for ING5 Gene
mRNA/cDNA for ING5 Gene
- 3 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000313552 5197 nts (view in UCSC)
- ENST00000406941 946 nts (view in UCSC)
- ENST00000433036 415 nts (view in UCSC)
- ENST00000445620 662 nts (view in UCSC)
- ENST00000474238 400 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ING5 - Starting at $85 >
- * ING5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ING5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ING5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ING5
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ING5
- Browse OriGene Inhibitory RNA Products For ING5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ING5
Clone products for research
- Applied Biological Materials (abm): Clones for ING5 - Starting at $45 >
- * ING5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ING5
- Addgene plasmids for ING5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ING5
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||
| SP5: |
Relevant External Links for ING5 Gene
- GeneLoc Exon Structure for
- ING5
Expression for ING5 Gene
This gene is overexpressed in NK cells (27.7), Liver (11.5), Monocytes (10.3), and Breast (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ING5 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ING5
SOURCE GeneReport for Unigene cluster for ING5 Gene:
Hs.529172mRNA Expression by UniProt/SwissProt for ING5 Gene:
Q8WYH8-ING5_HUMAN
Tissue specificity:
Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells.
Evidence on tissue expression from TISSUES for ING5 Gene
- Nervous system(4.5)
- Skin(4.4)
- Liver(4.2)
Primer products for research
-
OriGene qPCR primer pairs for ING5
-
OriGene qPCR primer pairs and template standards for ING5
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ING5 Gene
Orthologs for ING5 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ING5 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ING5 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ING5 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ING5 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ING5 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ing5 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ING5 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ING5 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ing5 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | ing5a 30 31 |
|
OneToMany | |
| ing5b 31 |
|
OneToMany | |||
| -- 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9293 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PHO23 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for ING5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for ING5 Gene
- ENSEMBL:
- Gene Tree for ING5 (if available)
- TreeFam:
- Gene Tree for ING5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ING5: view image
Paralogs for ING5 Gene
Variants for ING5 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ING5 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs146454591 | Benign: not provided | 241,709,346(+) |
C/T NM_032329.6(ING5):c.240C>T (p.Asp80=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv165e55 | CNV | loss | 17911159 |
| nsv1002941 | CNV | gain | 25217958 |
| nsv1006733 | CNV | gain | 25217958 |
| nsv1073033 | CNV | deletion | 25765185 |
| nsv1143973 | CNV | deletion | 24896259 |
| nsv508901 | CNV | insertion | 20534489 |
| nsv584974 | CNV | gain | 21841781 |
| nsv584975 | CNV | loss | 21841781 |
| nsv997984 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
27% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.47;
10.17% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ING5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ING5
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ING5 Gene
Disorders for ING5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ohdo syndrome, sbbys variant |
|
|
| atrophy of testis |
|
|
| ohdo syndrome |
|
|
| kleefstra syndrome 1 |
|
|
Search ING5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ING5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ING5 Gene
Publications for ING5 Gene
- p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. (PMID: 12750254) Shiseki M … Harris CC (Cancer research 2003) 2 3 4 23
- Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity. (PMID: 24065767) Lalonde ME … Côté J (Genes & development 2013) 3 4
- The inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effects. (PMID: 21750715) Zhang F … Müller-Tidow C (PloS one 2011) 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. (PMID: 18794358) Ullah M … Yang XJ (Molecular and cellular biology 2008) 3 4
ExternalLinks
Products for ING5 Gene
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- High-throughput Antibody Production Service
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals proteins and lysates for ING5
- Browse Antibodies
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- Abcam antibodies for ING5
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- Browse Recombinant Antibodies
- Invitrogen Antibodies for ING5 (AFLGC-ING5)
- VectorBuilder Custom and pre-made DNA vectors for ING5 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ING5 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ING5 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ING5 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ING5
- Addgene plasmids for ING5
- antibodies-online: Show 21 available ING5 Antibodies ranked by validation data
- Compare Top ING5 Antibodies
- antibodies-online: Search results for available ING5 related products ranked by validation data
- antibodies-online: Show 6 available ING5 Proteins ranked by validation data
- Compare Top ING5 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for ING5
- Search Santa Cruz Biotechnology (SCBT) for ING5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ING5
- Horizon Cell Lines for ING5
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ING5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ING5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ING5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ING5
Sources for ING5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB