Aliases for INE2 Gene

Subcategory (RNA class) for INE2 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for INE2 Gene

  • Inactivation Escape 2 2 3 5
  • INE2 2 5 165
  • Inactivation Escape 2 (Non-Protein Coding) 2 3
  • NCRNA00011 2 3
  • Non-Protein Coding RNA 11 2
  • NONHSAG054083.2 91
  • HSALNG0136795 164

External Ids for INE2 Gene

Previous GeneCards Identifiers for INE2 Gene

  • GC0XU990269
  • GC0XM015713
  • GC0XM013557

Summaries for INE2 Gene

GeneCards Summary for INE2 Gene

INE2 (Inactivation Escape 2) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with INE2 include Spinal Muscular Atrophy, Type I and Childhood Spinal Muscular Atrophy.

Additional gene information for INE2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for INE2 Gene

Genomics for INE2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for INE2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ015785 Enhancer 0.4 Ensembl 600.7 +1.2 1188 2.8 RFX1 CEBPA FOXA2 SPI1 INE2 lnc-AP1S2-1 CA5B CA5BP1 ZRSR2 PIR CLTRN CA5BP1-CA5B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around INE2 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the INE2 gene promoter:
  • CUTL1
  • En-1
  • FAC1
  • FOXO4
  • Meis-1
  • Meis-1a
  • Meis-1b
  • POU2F1
  • POU2F1a
  • RSRFC4

Genomic Locations for INE2 Gene

Genomic Locations for INE2 Gene
chrX:15,785,715-15,787,589
(GRCh38/hg38)
Size:
1,875 bases
Orientation:
Minus strand
chrX:15,803,839-15,805,712
(GRCh37/hg19)
Size:
1,874 bases
Orientation:
Minus strand

Genomic View for INE2 Gene

Genes around INE2 on UCSC Golden Path with GeneCards custom track
INE2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
INE2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INE2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INE2 Gene

Proteins for INE2 Gene

No data available for DME Specific Peptides for INE2 Gene

Domains & Families for INE2 Gene

Gene Families for INE2 Gene

genes like me logo Genes that share domains with INE2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for INE2 Gene

Function for INE2 Gene

Molecular function for INE2 Gene

GENATLAS Biochemistry:
EST transcript from a gene escaping inactivation
genes like me logo Genes that share phenotypes with INE2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INE2 Gene

Localization for INE2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for INE2 gene
Compartment Confidence
plasma membrane 1
extracellular 1
nucleus 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for INE2 Gene

Pathways & Interactions for INE2 Gene

PathCards logo

SuperPathways for INE2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for INE2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for INE2 Gene

Drugs & Compounds for INE2 Gene

No Compound Related Data Available

Transcripts for INE2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for INE2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E0D3_9606 lncRNA 1874 5

HGNC: 6061,

RefSeq: NR_002725,

Ensembl: ENST00000630399 (view in UCSC) ,

LNCipedia: INE2:1,

NONCODE: NONHSAT136363.2,

URS0000E9C2B4_9606 lncRNA 1875 1

LncBook: HSALNT0280481,

INE2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for INE2 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for INE2 Gene

No ASD Table

Relevant External Links for INE2 Gene

GeneLoc Exon Structure for
INE2

Expression for INE2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for INE2 Gene

mRNA expression in normal human tissues for INE2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for INE2

genes like me logo Genes that share expression patterns with INE2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INE2 Gene

Orthologs for INE2 Gene

Evolution for INE2 Gene

ENSEMBL:
Gene Tree for INE2 (if available)
TreeFam:
Gene Tree for INE2 (if available)

No data available for Orthologs for INE2 Gene

Paralogs for INE2 Gene

No data available for Paralogs for INE2 Gene

Variants for INE2 Gene

Additional dbSNP identifiers (rs#s) for INE2 Gene

Additional Variant Information for INE2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INE2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for INE2 Gene

Disorders for INE2 Gene

MalaCards: The human disease database

(2) MalaCards diseases for INE2 Gene - From: DISEASES

Disorder Aliases PubMed IDs
spinal muscular atrophy, type i
  • sma1
childhood spinal muscular atrophy
  • spinal muscular atrophies of childhood
- elite association - COSMIC cancer census association via MalaCards
Search INE2 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for INE2

genes like me logo Genes that share disorders with INE2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for INE2 Gene

Publications for INE2 Gene

  1. Escape from X inactivation of two new genes associated with DXS6974E and DXS7020E. (PMID: 9244435) Esposito T … Forabosco A (Genomics 1997) 2 3

Products for INE2 Gene

Sources for INE2 Gene