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Aliases for INE1 Gene

Subcategory (RNA class) for INE1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for INE1 Gene

  • Inactivation Escape 1 (Non-Protein Coding) 2 3 5
  • Non-Protein Coding RNA 10 2
  • NCRNA00010 3
  • DXS6974E 4

External Ids for INE1 Gene

Previous GeneCards Identifiers for INE1 Gene

  • GC0XU990270
  • GC0XP045890
  • GC0XP046110
  • GC0XP046820
  • GC0XP046950
  • GC0XP047064
  • GC0XP044774

Summaries for INE1 Gene

Entrez Gene Summary for INE1 Gene

  • X chromosome inactivation provides dosage compensation for the expression level of X-linked genes from the single X in males and the two in females. This X chromosome gene is intronless and was identified because its transcription escapes X inactivation in females. This gene does not make a protein.[provided by RefSeq, May 2010]

GeneCards Summary for INE1 Gene

INE1 (Inactivation Escape 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for INE1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for INE1 Gene

Genomics for INE1 Gene

GeneHancer (GH) Regulatory Elements for INE1 Gene

Promoters and enhancers for INE1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI047216 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 35.1 +13.7 13671 5 HDGF PKNOX1 CLOCK ARNT SIN3A FEZF1 ZNF2 IRF4 YY1 POLR2B CDK16 LOC105373194 ZNF81 LOC100113397 INE1 ZNF182 ZNF674-AS1 LINC01560 USP11 ZNF674
GH0XI047657 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 34.8 +453.9 453891 2.9 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B UXT UXT-AS1 INE1 ZNF81 ENSG00000204620 UBA1 FTSJ1 RBM3 ZNF182 RBM10
GH0XI047231 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 27.5 +29.2 29170 4.7 SMAD1 NEUROD1 SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B IRF4 YY1 POLR2B USP11 INE1 ZNF81 SNORA11C LOC100419232 UXT WASF4P UBA1 LINC01560 GC0XP047244
GH0XI046544 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 23.5 -658.4 -658372 4.6 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B ZNF674-AS1 ZNF674 LOC100113397 LINC01560 INE1 SLC9A7 NUS1P1 ZNF41 KRBOX4 ENSG00000277721
GH0XI047143 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 24.4 -59.5 -59546 3.8 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 ZNF143 FOS NDUFB11 RBM10 RGN INE1 UBA1 ZNF81 ARAF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around INE1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the INE1 gene promoter:

Genomic Locations for INE1 Gene

Genomic Locations for INE1 Gene
chrX:47,204,848-47,205,865
(GRCh38/hg38)
Size:
1,018 bases
Orientation:
Plus strand
chrX:47,064,247-47,065,264
(GRCh37/hg19)

Genomic View for INE1 Gene

Genes around INE1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INE1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INE1 Gene

Proteins for INE1 Gene

  • Protein details for INE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15225-INE1_HUMAN
    Recommended name:
    Putative inactivation escape 1 protein
    Protein Accession:
    O15225
    Secondary Accessions:
    • Q5JRR7
    • Q6NSX0

    Protein attributes for INE1 Gene

    Size:
    51 amino acids
    Molecular mass:
    5365 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INE1 Gene

Post-translational modifications for INE1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for INE1 Gene

Domains & Families for INE1 Gene

Protein Domains for INE1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for INE1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with INE1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for INE1 Gene

Function for INE1 Gene

Molecular function for INE1 Gene

GENATLAS Biochemistry:
EST transcript from a gene escaping inactivation

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INE1 Gene

Localization for INE1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for INE1 gene
Compartment Confidence
extracellular 3
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for INE1 Gene

Pathways & Interactions for INE1 Gene

No Data Available

Interacting Proteins for INE1 Gene

Gene Ontology (GO) - Biological Process for INE1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for INE1 Gene

Drugs & Compounds for INE1 Gene

No Compound Related Data Available

Transcripts for INE1 Gene

mRNA/cDNA for INE1 Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(826) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for INE1 Gene

Inactivation escape 1 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for INE1 Gene

No ASD Table

Relevant External Links for INE1 Gene

GeneLoc Exon Structure for
INE1
ECgene alternative splicing isoforms for
INE1

Expression for INE1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for INE1 Gene

NURSA nuclear receptor signaling pathways regulating expression of INE1 Gene:

INE1

SOURCE GeneReport for Unigene cluster for INE1 Gene:

Hs.657350

mRNA Expression by UniProt/SwissProt for INE1 Gene:

O15225-INE1_HUMAN
Tissue specificity: Highly expressed in pancreas, heart and liver followed by brain, placenta, lung, skeletal muscle and kidney. Mostly expressed in females.
genes like me logo Genes that share expression patterns with INE1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INE1 Gene

Orthologs for INE1 Gene

Evolution for INE1 Gene

ENSEMBL:
Gene Tree for INE1 (if available)
TreeFam:
Gene Tree for INE1 (if available)

No data available for Orthologs for INE1 Gene

Paralogs for INE1 Gene

No data available for Paralogs for INE1 Gene

Variants for INE1 Gene

Sequence variations from dbSNP and Humsavar for INE1 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs140950898 conflicting-interpretations-of-pathogenicity, uncertain-significance, Arthrogryposis multiplex congenita, distal, X-linked, not specified 47,203,607(+) G/A upstream_transcript_variant
rs147825775 conflicting-interpretations-of-pathogenicity, Arthrogryposis multiplex congenita, distal, X-linked 47,203,005(+) C/T upstream_transcript_variant
rs150198324 uncertain-significance, Arthrogryposis multiplex congenita, distal, X-linked 47,203,664(+) C/A upstream_transcript_variant
rs150574055 benign, Arthrogryposis multiplex congenita, distal, X-linked 47,206,074(+) C/G downstream_transcript_variant
rs2070169 benign, Arthrogryposis multiplex congenita, distal, X-linked, not specified 47,203,135(+) G/A upstream_transcript_variant

Additional Variant Information for INE1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INE1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for INE1 Gene

Disorders for INE1 Gene

Additional Disease Information for INE1

No disorders were found for INE1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for INE1 Gene

Publications for INE1 Gene

  1. Escape from X inactivation of two new genes associated with DXS6974E and DXS7020E. (PMID: 9244435) Esposito T … Forabosco A (Genomics 1997) 2 3 4 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for INE1 Gene

Sources for INE1 Gene

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