Aliases for INAFM2 Gene

Aliases for INAFM2 Gene

  • InaF Motif Containing 2 2 3 5
  • Osteogenesis Up-Regulated Transcript 1 2 3 4
  • OGU1 2 3 4
  • Putative Transmembrane Protein INAFM2 3 4
  • InaF-Motif-Containing Protein 2 3 4
  • LINC00984 3 4
  • Long Intergenic Non-Protein Coding RNA 984 2
  • Osteogenesis Upregulating Transcript 1 3
  • InaF-Motif Containing 2 2
  • INAFM2 5

External Ids for INAFM2 Gene

Previous HGNC Symbols for INAFM2 Gene

  • LINC00984

Summaries for INAFM2 Gene

GeneCards Summary for INAFM2 Gene

INAFM2 (InaF Motif Containing 2) is a Protein Coding gene. Diseases associated with INAFM2 include Alzheimer Disease 5.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for INAFM2 Gene

Genomics for INAFM2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for INAFM2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around INAFM2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for INAFM2

Genomic Locations for INAFM2 Gene

Latest Assembly
chr15:40,323,669-40,326,715
(GRCh38/hg38)
Size:
3,047 bases
Orientation:
Plus strand

Previous Assembly
chr15:40,615,893-40,618,916
(GRCh37/hg19 by Entrez Gene)
Size:
3,024 bases
Orientation:
Plus strand

chr15:40,617,417-40,618,916
(GRCh37/hg19 by Ensembl)
Size:
1,500 bases
Orientation:
Plus strand

Genomic View for INAFM2 Gene

Genes around INAFM2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
INAFM2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for INAFM2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for INAFM2 Gene

Proteins for INAFM2 Gene

  • Protein details for INAFM2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0DMQ5-INAM2_HUMAN
    Recommended name:
    Putative transmembrane protein INAFM2
    Protein Accession:
    P0DMQ5

    Protein attributes for INAFM2 Gene

    Size:
    153 amino acids
    Molecular mass:
    15439 Da
    Quaternary structure:
    No Data Available

neXtProt entry for INAFM2 Gene

Post-translational modifications for INAFM2 Gene

No Post-translational modifications

Other Protein References for INAFM2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for INAFM2 Gene

Domains & Families for INAFM2 Gene

Gene Families for INAFM2 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for INAFM2 Gene

InterPro:
genes like me logo Genes that share domains with INAFM2: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for INAFM2 Gene

Function for INAFM2 Gene

Phenotypes From GWAS Catalog for INAFM2 Gene

Gene Ontology (GO) - Molecular Function for INAFM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005246 calcium channel regulator activity IBA 21873635
genes like me logo Genes that share ontologies with INAFM2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for INAFM2 Gene

Localization for INAFM2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for INAFM2 Gene

Membrane. Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for INAFM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with INAFM2: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for INAFM2 Gene

Pathways & Interactions for INAFM2 Gene

PathCards logo

SuperPathways for INAFM2 Gene

No Data Available

Interacting Proteins for INAFM2 Gene

Gene Ontology (GO) - Biological Process for INAFM2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for INAFM2 Gene

Drugs & Compounds for INAFM2 Gene

No Compound Related Data Available

Transcripts for INAFM2 Gene

mRNA/cDNA for INAFM2 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for INAFM2

Alternative Splicing Database (ASD) splice patterns (SP) for INAFM2 Gene

No ASD Table

Relevant External Links for INAFM2 Gene

GeneLoc Exon Structure for
INAFM2

Expression for INAFM2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for INAFM2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for INAFM2

genes like me logo Genes that share expression patterns with INAFM2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for INAFM2 Gene

Orthologs for INAFM2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for INAFM2 Gene

Organism Taxonomy Gene Similarity Type Details
Cow
(Bos Taurus)
Mammalia LOC101905957 29
  • 94.08 (n)
Species where no ortholog for INAFM2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for INAFM2 Gene

ENSEMBL:
Gene Tree for INAFM2 (if available)
TreeFam:
Gene Tree for INAFM2 (if available)
Alliance of Genome Resources:
Additional Orthologs for INAFM2

Paralogs for INAFM2 Gene

No data available for Paralogs for INAFM2 Gene

Variants for INAFM2 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for INAFM2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for INAFM2 Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV loss 18971310
nsv1070266 CNV deletion 25765185
nsv510660 CNV deletion 20534489
nsv827305 CNV gain 20364138

Additional Variant Information for INAFM2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
INAFM2
Leiden Open Variation Database (LOVD)
INAFM2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for INAFM2 Gene

Disorders for INAFM2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for INAFM2 Gene - From: COP

Disorder Aliases PubMed IDs
alzheimer disease 5
  • ad5
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for INAFM2

genes like me logo Genes that share disorders with INAFM2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for INAFM2 Gene

Publications for INAFM2 Gene

  1. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. (PMID: 19531736) Kikuchi K … Aizawa Y (Nucleic acids research 2009) 2 3 4
  2. Interactive associations of the INAFM2 rs67839313 variant and egg consumption with type 2 diabetes mellitus and fasting blood glucose in a Chinese population: A family-based study. (PMID: 33333222) Wang X … Hu Y (Gene 2021) 3
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

Products for INAFM2 Gene

Sources for INAFM2 Gene