Aliases for IMPG2 Gene
External Ids for IMPG2 Gene
Previous GeneCards Identifiers for IMPG2 Gene
The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.[provided by RefSeq, Mar 2011]
GeneCards Summary for IMPG2 Gene
IMPG2 (Interphotoreceptor Matrix Proteoglycan 2) is a Protein Coding gene. Diseases associated with IMPG2 include Macular Dystrophy, Vitelliform, 5 and Retinitis Pigmentosa 56. Among its related pathways are ERK Signaling and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include heparin binding and hyaluronic acid binding. An important paralog of this gene is IMPG1.
UniProtKB/Swiss-Prot for IMPG2 Gene
Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.