Aliases for ILVBL Gene
External Ids for ILVBL Gene
Previous GeneCards Identifiers for ILVBL Gene
The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for ILVBL Gene
ILVBL (IlvB Acetolactate Synthase Like) is a Protein Coding gene. Diseases associated with ILVBL include Balanoposthitis and Balanitis. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and thiamine pyrophosphate binding. An important paralog of this gene is HACL1.
UniProtKB/Swiss-Prot Summary for ILVBL Gene
Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway.