Aliases for IL9R Gene
External Ids for IL9R Gene
Previous GeneCards Identifiers for IL9R Gene
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL9R Gene
IL9R (Interleukin 9 Receptor) is a Protein Coding gene. Diseases associated with IL9R include Bronchitis and Asthma. Among its related pathways are Akt Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include interleukin-9 receptor activity and interleukin-9 binding. An important paralog of this gene is IL2RB.
UniProtKB/Swiss-Prot Summary for IL9R Gene
This is a receptor for interleukin-9.