Aliases for IL9 Gene
External Ids for IL9 Gene
Previous GeneCards Identifiers for IL9 Gene
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL9 Gene
IL9 (Interleukin 9) is a Protein Coding gene. Diseases associated with IL9 include Severe Combined Immunodeficiency, X-Linked and Asthma. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and NF-KappaB Family Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and cytokine receptor binding.
UniProtKB/Swiss-Prot Summary for IL9 Gene
Supports IL-2 independent and IL-4 independent growth of helper T-cells.