Aliases for IL9 Gene
External Ids for IL9 Gene
Previous GeneCards Identifiers for IL9 Gene
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL9 Gene
IL9 (Interleukin 9) is a Protein Coding gene. Diseases associated with IL9 include Severe Combined Immunodeficiency, X-Linked and Asthma. Among its related pathways are Nanog in Mammalian ESC Pluripotency and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and cytokine receptor binding.
UniProtKB/Swiss-Prot Summary for IL9 Gene
Supports IL-2 independent and IL-4 independent growth of helper T-cells.