IL4I1 Gene (Protein Coding)

Interleukin 4 Induced 1

GC19M049890
GIFtS:
37
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found ... See more...

Aliases for IL4I1 Gene

Aliases for IL4I1 Gene

  • Interleukin 4 Induced 1 2 3 5
  • FIG1 2 3 4
  • IL4-Induced Protein 1 3 4
  • L-Amino-Acid Oxidase 3 4
  • LAAO 3 4
  • LAO 3 4
  • Interleukin-4-Induced Protein 1 4
  • Interleukin Four Induced 1 3
  • Fig-1 Protein 3
  • Protein Fig-1 4
  • EC 1.4.3.2 4
  • IL4I1 5
  • HFIG1 4

External Ids for IL4I1 Gene

Previous GeneCards Identifiers for IL4I1 Gene

  • GC19U990319
  • GC19M050741
  • GC19M055069
  • GC19M055065
  • GC19M055085
  • GC19M055070
  • GC19M055090
  • GC19M055092
  • GC19M055094
  • GC19M055096
  • GC19M055098
  • GC19M055099
  • GC19M055100
  • GC19M055106
  • GC19M055108
  • GC19M050392
  • GC19M046769

Summaries for IL4I1 Gene

Entrez Gene Summary for IL4I1 Gene

  • This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

GeneCards Summary for IL4I1 Gene

IL4I1 (Interleukin 4 Induced 1) is a Protein Coding gene. Diseases associated with IL4I1 include Striatonigral Degeneration, Infantile and Corneal Abscess. Among its related pathways are Tyrosine metabolism and Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and L-amino-acid oxidase activity. An important paralog of this gene is KDM1A.

UniProtKB/Swiss-Prot Summary for IL4I1 Gene

  • Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).

Additional gene information for IL4I1 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IL4I1 Gene

Genomics for IL4I1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for IL4I1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH19J049926 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.6 582 4.8 RNF2 ARHGAP35 SP1 HNRNPL CREB1 PRDM10 REST ZNF629 TFE3 IKZF1 NUP62 ATF5 IL4I1 lnc-NUP62-1 POLD1 PRR12 IRF3 PTOV1-AS2 SNORD35A SNRNP70
GH19J049894 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 603.8 +32.9 32889 4 SP1 TFE3 LEF1 BACH1 JUND LARP7 STAT3 PRDM1 ZNF143 RELA IL4I1 NUP62 POLD1 AKT1S1 MED25 NR1H2 PNKP PTOV1-AS2 ATF5 TBC1D17
GH19J049903 Promoter 0.5 EPDnew 600.3 +25.9 25856 0.1 FOSL1 BATF IL4I1 piR-31100 MIR4750 AKT1S1 ATF5 lnc-NUP62-1
GH19J050003 Enhancer 1 Ensembl ENCODE 11.4 -75.1 -75062 2.4 SP1 PRDM10 ZNF629 IKZF1 JUND PRDM1 RELA MTA1 REST IKZF2 VRK3 NR1H2 RRAS DKKL1 ZNF473 PTOV1 NUP62 ATF5 IL4I1 ENSG00000221125
GH19J049983 Enhancer 0.9 Ensembl ENCODE 11.8 -54.2 -54208 0.3 CTCF REST ZNF143 RAD21 TRIM22 SCRT2 CBX3 RUNX3 GATAD2A ZNF444 lnc-ZNF473-4 SIGLEC16 SIGLEC11 ENSG00000221125 IL4I1 NUP62 ATF5 lnc-SIGLEC11-1 VRK3 ZNF473
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around IL4I1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for IL4I1

Top Transcription factor binding sites by QIAGEN in the IL4I1 gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • p300
  • Sp1
  • SRY

Genomic Locations for IL4I1 Gene

Genomic Locations for IL4I1 Gene
chr19:49,889,654-49,929,539
(GRCh38/hg38)
Size:
39,886 bases
Orientation:
Minus strand
chr19:50,392,911-50,432,796
(GRCh37/hg19)
Size:
39,886 bases
Orientation:
Minus strand

Genomic View for IL4I1 Gene

Genes around IL4I1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IL4I1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IL4I1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for IL4I1 Gene

Proteins for IL4I1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for IL4I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96RQ9-OXLA_HUMAN
    Recommended name:
    L-amino-acid oxidase
    Protein Accession:
    Q96RQ9
    Secondary Accessions:
    • Q1WMJ3
    • Q4GZN1
    • Q4GZN2
    • Q6P2Q3
    • Q8TEM5
    • Q96RQ8

    Protein attributes for IL4I1 Gene

    Size:
    567 amino acids
    Molecular mass:
    62881 Da
    Cofactor:
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB84923.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI54291.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI54292.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI54293.1; Type=Erroneous initiation; Evidence={ECO:0000305};
    Miscellaneous:
    • [Isoform 2]: Uses the promoter of the upstream NUP62 gene and shares the first 2 non-coding exons with NUP62.

    Three dimensional structures from OCA and Proteopedia for IL4I1 Gene

    Alternative splice isoforms for IL4I1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IL4I1 Gene

Protein Expression for IL4I1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for IL4I1 Gene

  • Glycosylation at Asn54, Asn134, Asn220, and Asn559
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect

Other Protein References for IL4I1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IL4I1 Gene

Domains & Families for IL4I1 Gene

Gene Families for IL4I1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted secreted proteins

Protein Domains for IL4I1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IL4I1 Gene

GenScript: Design optimal peptide antigens:
  • Interleukin 4 induced 1 (A2RRH1_HUMAN)
  • Protein Fig-1 (OXLA_HUMAN)
  • Interleukin-4 induced protein-1 variant 2 (Q1WMJ3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q96RQ9

UniProtKB/Swiss-Prot:

OXLA_HUMAN :
  • Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
Family:
  • Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
genes like me logo Genes that share domains with IL4I1: view

Function for IL4I1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for IL4I1 Gene

UniProtKB/Swiss-Prot Function:
Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=an L-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4(+); Xref=Rhea:RHEA:13781, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:28938, ChEBI:CHEBI:35179, ChEBI:CHEBI:59869; EC=1.4.3.2;.
UniProtKB/Swiss-Prot Induction:
By IL4/interleukin-4.

Enzyme Numbers (IUBMB) for IL4I1 Gene

Phenotypes From GWAS Catalog for IL4I1 Gene

Gene Ontology (GO) - Molecular Function for IL4I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001716 L-amino-acid oxidase activity IBA 21873635
GO:0016491 oxidoreductase activity IEA,IBA 21873635
GO:0046592 polyamine oxidase activity IBA 21873635
genes like me logo Genes that share ontologies with IL4I1: view
genes like me logo Genes that share phenotypes with IL4I1: view

Animal Models for IL4I1 Gene

MGI Knock Outs for IL4I1:
  • Il4i1 Il4i1<tm1b(EUCOMM)Wtsi>
  • Il4i1 Il4i1<tm1Lex>

Animal Model Products

  • Taconic Biosciences Mouse Models for IL4I1

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IL4I1

No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for IL4I1 Gene

Localization for IL4I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for IL4I1 Gene

[Isoform 1]: Lysosome.
[Isoform 2]: Lysosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IL4I1 gene
Compartment Confidence
extracellular 4
lysosome 4
plasma membrane 3
cytoskeleton 2
mitochondrion 2
nucleus 2
endoplasmic reticulum 2
cytosol 2
peroxisome 1
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for IL4I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005764 lysosome IEA --
genes like me logo Genes that share ontologies with IL4I1: view

Pathways & Interactions for IL4I1 Gene

genes like me logo Genes that share pathways with IL4I1: view

Gene Ontology (GO) - Biological Process for IL4I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006559 L-phenylalanine catabolic process TAS --
GO:0009063 cellular amino acid catabolic process IBA 21873635
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with IL4I1: view

No data available for SIGNOR curated interactions for IL4I1 Gene

Drugs & Compounds for IL4I1 Gene

Products:

  1. Drug

(24) Drugs for IL4I1 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FAD Approved Pharma Target 0
Citric acid Approved, Vet_approved Nutra Activator, Agonist, Target 1509
Oxygen Approved, Vet_approved Pharma 0
Phenylalanine Approved, Investigational Nutra 256
Tyrosine Approved, Investigational Nutra 1044

(16) Additional Compounds for IL4I1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
3-Methyl-2-oxovaleric acid
  • 2-oxo-3-Methyl-N-valeric acid
  • 2-oxo-3-Methylpentanoic acid
  • 2-oxo-3-Methylvalerate
  • 2-oxo-3-Methylvaleric acid
  • 2-Oxoisoleucine
 1460-34-0
Indolepyruvate
  • Indole-3-pyruvic acid
  • Indolepyruvic acid
  • Indole-3-pyruvate
  • (indol-3-yl)Pyruvic acid
 35656-49-6
Oxalacetic acid
  • 2-Oxobutanedioic acid
  • 2-Oxosuccinic acid
  • 3-Carboxy-3-oxopropanoic acid
  • keto-Succinic acid
  • Ketosuccinic acid
 328-42-7
genes like me logo Genes that share compounds with IL4I1: view

Transcripts for IL4I1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for IL4I1 Gene

4 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IL4I1

Alternative Splicing Database (ASD) splice patterns (SP) for IL4I1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12
SP1:
SP2:
SP3: - - -
SP4: - - - - -
SP5: - - - -
SP6: - -
SP7: -
SP8:
SP9:

Relevant External Links for IL4I1 Gene

GeneLoc Exon Structure for
IL4I1

Expression for IL4I1 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IL4I1 Gene

mRNA expression in normal human tissues for IL4I1 Gene
mRNA expression by BioGPS for IL4I1 GenemRNA expression by GTEx for IL4I1 Gene

mRNA differential expression in normal tissues according to GTEx for IL4I1 Gene

This gene is overexpressed in Testis (x8.3).

Protein differential expression in normal tissues from HIPED for IL4I1 Gene

This gene is overexpressed in Lung (20.7), Lymph node (13.2), Peripheral blood mononuclear cells (9.9), and Testis (7.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IL4I1 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for IL4I1

SOURCE GeneReport for Unigene cluster for IL4I1 Gene:

Hs.741750

mRNA Expression by UniProt/SwissProt for IL4I1 Gene:

Q96RQ9-OXLA_HUMAN
Tissue specificity: Isoform 1 is primarily found in immune tissues.

Evidence on tissue expression from TISSUES for IL4I1 Gene

  • Spleen(4.5)
  • Nervous system(4.4)
  • Liver(4.4)
  • Skin(2.8)
  • Blood(2.8)
  • Heart(2.5)
  • Lung(2.3)
  • Intestine(2.3)
  • Lymph node(2.3)
  • Muscle(2.3)
genes like me logo Genes that share expression patterns with IL4I1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for IL4I1 Gene

Orthologs for IL4I1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for IL4I1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia IL4I1 30 31
  • 98.51 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia IL4I1 30 31
  • 81.79 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Il4i1 30 17 31
  • 79.23 (n)
 OneToOne
Il4i1b 17
Rat
(Rattus norvegicus)
 Mammalia LOC100360621 30
  • 77.97 (n)
Cow
(Bos Taurus)
 Mammalia IL4I1 31
  • 74 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia IL4I1 31
  • 58 (a)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia IL4I1 31
  • 44 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves IL4I1 31
  • 37 (a)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia -- 31
  • 39 (a)
 OneToMany
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia LOC100493881 30
  • 49.15 (n)
LOC394934 30
African clawed frog
(Xenopus laevis)
 Amphibia Xl.1078 30
Zebrafish
(Danio rerio)
 Actinopterygii si:dkey-40g16.6 30
  • 49.46 (n)
IL4I1 31
  • 41 (a)
 OneToOne
Rainbow Trout
(Oncorhynchus mykiss)
 Actinopterygii Omy.11911 30
Bread mold
(Neurospora crassa)
 Ascomycetes NCU01066 30
  • 45.52 (n)
Sea Vase
(Ciona intestinalis)
 Ascidiacea Cin.2768 30
Species where no ortholog for IL4I1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for IL4I1 Gene

ENSEMBL:
Gene Tree for IL4I1 (if available)
TreeFam:
Gene Tree for IL4I1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for IL4I1: view image

Paralogs for IL4I1 Gene

Paralogs for IL4I1 Gene

genes like me logo Genes that share paralogs with IL4I1: view

Variants for IL4I1 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for IL4I1 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
708003 Benign: not provided 49,908,948(-) G/GTGC INFRAME_INSERTION,INTRON_VARIANT
713586 Likely Benign: not provided 49,909,145(-) G/C SYNONYMOUS_VARIANT,INTRON_VARIANT
718162 Benign: not provided 49,909,531(-) C/T MISSENSE_VARIANT,INTRON_VARIANT
718364 Likely Benign: not provided 49,908,425(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT
719935 Benign: not provided 49,908,290(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for IL4I1 Gene

Structural Variations from Database of Genomic Variants (DGV) for IL4I1 Gene

Variant ID Type Subtype PubMed ID
dgv53n68 CNV loss 17160897
dgv54n68 CNV loss 17160897
esv3583457 CNV loss 25503493
esv3644628 CNV gain 21293372
esv3644630 CNV gain 21293372
esv996372 CNV deletion 20482838
nsv1058623 CNV gain 25217958
nsv1065648 CNV gain 25217958
nsv1131436 CNV deletion 24896259
nsv1140251 OTHER inversion 24896259
nsv2519 CNV deletion 18451855
nsv458720 CNV gain 19166990
nsv524068 CNV loss 19592680
nsv579910 CNV gain 21841781
nsv7309 OTHER inversion 18451855
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Variation tolerance for IL4I1 Gene

Residual Variation Intolerance Score: 45.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.05; 37.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IL4I1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IL4I1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL4I1 Gene

Disorders for IL4I1 Gene

MalaCards: The human disease database

(21) MalaCards diseases for IL4I1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
striatonigral degeneration, infantile
  • sndi
corneal abscess
subclavian steal syndrome
  • subclavian artery stenosis
striatonigral degeneration
esophageal tuberculosis
  • tuberculosis of esophagus
- elite association - COSMIC cancer census association via MalaCards
Search IL4I1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for IL4I1

Genetic Association Database
(GAD)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with IL4I1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for IL4I1 Gene

Publications for IL4I1 Gene

  1. Characterization of the human homolog of the IL-4 induced gene-1 (Fig1). (PMID: 12031486) Chavan SS … Chu CC (Biochimica et biophysica acta 2002) 2 3 4
  2. Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation. (PMID: 17356132) Boulland ML … Castellano F (Blood 2007) 3 23
  3. Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes. (PMID: 16029492) Wiemann S … Poustka A (BMC biology 2005) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z … Henzel WJ (Protein science : a publication of the Protein Society 2004) 3 4

ExternalLinks

View latest publications for IL4I1 gene in Mastermind

Products for IL4I1 Gene

  • Signalway ELISA kits for IL4I1

Sources for IL4I1 Gene