Aliases for IL32 Gene
External Ids for IL32 Gene
Previous GeneCards Identifiers for IL32 Gene
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL32 Gene
IL32 (Interleukin 32) is a Protein Coding gene. Diseases associated with IL32 include Pancreatic Cancer and Granulomatosis With Polyangiitis. Among its related pathways are PEDF Induced Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include cytokine activity.
UniProtKB/Swiss-Prot Summary for IL32 Gene
Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.