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The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel dise... See more...
Aliases for IL18RAP Gene
Aliases for IL18RAP Gene
- Interleukin 18 Receptor Accessory Protein 2 3 5
- Interleukin-18 Receptor Accessory Protein 3 4
- CD218 Antigen-Like Family Member B 3 4
- IL-18 Receptor Accessory Protein 3 4
- Interleukin-18 Receptor Beta 3 4
- Interleukin-1 Receptor 7 3 4
- IL-18R-Beta 3 4
- IL-18Rbeta 3 4
- IL-18RAcP 3 4
- IL-1RAcPL 3 4
- CDw218b 3 4
- IL-1R-7 3 4
- CD218b 2 3
External Ids for IL18RAP Gene
- HGNC: 5989
- NCBI Entrez Gene: 8807
- Ensembl: ENSG00000115607
- OMIM®: 604509
- UniProtKB/Swiss-Prot: O95256
Previous GeneCards Identifiers for IL18RAP Gene
- GC02P100899
- GC02P101487
- GC02P102639
- GC02P102656
- GC02P102493
- GC02P102401
- GC02P103035
- GC02P096799
Summaries for IL18RAP Gene
-
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
GeneCards Summary for IL18RAP Gene
IL18RAP (Interleukin 18 Receptor Accessory Protein) is a Protein Coding gene. Diseases associated with IL18RAP include Crohn's Disease and Inflammatory Bowel Disease. Among its related pathways are Innate Immune System and PEDF Induced Signaling. An important paralog of this gene is IL1RAPL2.
UniProtKB/Swiss-Prot Summary for IL18RAP Gene
-
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
Additional gene information for IL18RAP Gene
- HGNC (5989)
- NCBI Entrez Gene (8807)
- Ensembl (ENSG00000115607)
- OMIM® (604509)
- UniProtKB/Swiss-Prot (O95256)
- Open Targets Platform(ENSG00000115607)
- Monarch Initiative
- Search for IL18RAP at DataMed
- Search for IL18RAP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IL18RAP Gene
Genomics for IL18RAP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for IL18RAP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around IL18RAP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for IL18RAP
- Top Transcription factor binding sites by QIAGEN in the IL18RAP gene promoter:
-
- AML1a
- AREB6
- Evi-1
- GATA-1
- ISGF-3
- NF-1
- NF-1/L
- RelA
Genomic Locations for IL18RAP Gene
Latest Assembly
- chr2:102,418,550-102,452,568
- (GRCh38/hg38)
- Size:
- 34,019 bases
- Orientation:
- Plus strand
Previous Assembly
- chr2:103,035,250-103,069,025
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 33,776 bases
- Orientation:
- Plus strand
- chr2:103,035,149-103,069,025
- (GRCh37/hg19 by Ensembl)
- Size:
- 33,877 bases
- Orientation:
- Plus strand
Genomic View for IL18RAP Gene
Genes around IL18RAP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q12.1 by HGNC
- 2q12.1 by Entrez Gene
- 2q12.1 by Ensembl
IL18RAP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IL18RAP Gene
Proteins for IL18RAP Gene
-
Protein details for IL18RAP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95256-I18RA_HUMAN
- Recommended name:
- Interleukin-18 receptor accessory protein
- Protein Accession:
- O95256
- B2RPJ3
- Q2QDE5
- Q3KPE7
- Q3KPE8
- Q53TT4
- Q53TU5
Protein attributes for IL18RAP Gene
- Size:
- 599 amino acids
- Molecular mass:
- 68310 Da
- Quaternary structure:
-
- Forms a ternary complex with IL18 and IL18R1 (PubMed:14528293, PubMed:25500532). Within this complex, IL18R1 is involved in ligand-binding and IL18RAP in signaling leading to NF-kappa-B and JNK activation (Probable).
Post-translational modifications for IL18RAP Gene
- N-glycosylated.
-
Glycosylation at Asn152, Asn21, Asn119, and Asn345
- NX_O95256 (NX_O95256-1)
- Modification sites at PhosphoSitePlus
Other Protein References for IL18RAP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for IL18RAP
- Novus Biologicals Antibodies for IL18RAP
-
Abcam antibodies for IL18RAP
- Invitrogen Antibodies for IL18RAP (AFLGC-IL18RAP)
-
Custom Antibody ServicesProSci Antibodies for IL18RAP
-
Santa Cruz Biotechnology (SCBT) Antibodies for IL18RAP
- Sino Biological Antibodies for IL18RAP
Protein products for research
- G Biosciences Human IL-18RAP, Lyophilized
-
OriGene Purified Proteins for IL18RAP
- Search Origene for MassSpec and Protein Over-expression Lysates for IL18RAP
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- Novus Biologicals lysates for IL18RAP
- Sino Biological Recombinant Proteins for IL18RAP
- Sino Biological Cell Lysates for IL18RAP
- ProSpec Recombinant Proteins for IL18RAP
-
ProSci Proteins for IL18RAP
-
Abcam proteins for IL18RAP
Assay products for research
- RayBiotech Human IL-18 R beta ELISA
- antibodies-online: Show 13 available IL18RAP Elisa Kits ranked by validation data
- Compare Top IL18RAP Elisa Kits
-
Quality Products:
-
Abcam assays for IL18RAP
- Sino Biological Assays for IL18RAP
No data available for DME Specific Peptides for IL18RAP Gene
Domains & Families for IL18RAP Gene
Gene Families for IL18RAP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- CD markers
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for IL18RAP Gene
- InterPro:
- Blocks:
-
- Interleukin-1 receptor type I family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for IL18RAP Gene
- GenScript: Design optimal peptide antigens:
-
- Interleukin-18 receptor beta (I18RA_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O95256UniProtKB/Swiss-Prot:
I18RA_HUMAN :- The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
- Belongs to the interleukin-1 receptor family.
- Domain:
-
- The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
- Family:
-
- Belongs to the interleukin-1 receptor family.
Function for IL18RAP Gene
Molecular function for IL18RAP Gene
- UniProtKB/Swiss-Prot Function:
- Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide; Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU00204};.
- UniProtKB/Swiss-Prot Induction:
- Induced by IFN-alpha and IL12/interleukin-12 in natural killer (NK) cells and T-cells.
Enzyme Numbers (IUBMB) for IL18RAP Gene
Phenotypes From GWAS Catalog for IL18RAP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 32814053 |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0042008 | interleukin-18 receptor activity | IDA | 25500532 |
| GO:0050135 | NAD(P)+ nucleosidase activity | IEA | -- |
| GO:0061809 | NAD+ nucleotidase, cyclic ADP-ribose generating | IEA | -- |
Phenotypes for IL18RAP Gene
- MGI mutant phenotypes for IL18RAP:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for IL18RAP:
Animal Models for IL18RAP Gene
Animal Models for research
-
Taconic Biosciences Mouse Models for IL18RAP
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for IL18RAP - Starting at $85 >
- * IL18RAP CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for IL18RAP
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-
Santa Cruz Biotechnology (SCBT) CRISPR for IL18RAP
miRNA for IL18RAP Gene
- miRTarBase miRNAs that target IL18RAP
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IL18RAP
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Clone products for research
- Applied Biological Materials (abm): Clones for IL18RAP - Starting at $45 >
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- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for IL18RAP
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Cell Lines for research
-
Horizon Cell Lines for IL18RAP
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IL18RAP Gene
Localization for IL18RAP Gene
Subcellular locations from UniProtKB/Swiss-Prot for IL18RAP Gene
- Cell membrane. Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 3 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0045092 | interleukin-18 receptor complex | IDA | 25500532 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IL18RAP Gene
Pathways & Interactions for IL18RAP Gene
Pathways by source for IL18RAP Gene
1 Sino Biological pathway for IL18RAP Gene
3 BioSystems pathways for IL18RAP Gene
3 Reactome pathways for IL18RAP Gene
3 KEGG pathways for IL18RAP Gene
2 R&D Systems pathways for IL18RAP Gene
Interacting Proteins for IL18RAP Gene
Selected Interacting proteins:
O95256-I18RA_HUMAN
ENSP00000264260
for IL18RAP Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for IL18RAP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006954 | inflammatory response | TAS,IEA | -- |
| GO:0006955 | immune response | TAS | 9792649 |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0008283 | cell proliferation | IEA | -- |
| GO:0035655 | interleukin-18-mediated signaling pathway | TAS | -- |
No data available for SIGNOR curated interactions for IL18RAP Gene
Drugs & Compounds for IL18RAP Gene
No Compound Related Data Available
Drug products for research
- G Biosciences Human IL-18RAP, Lyophilized
Transcripts for IL18RAP Gene
mRNA/cDNA for IL18RAP Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000264260 2773 nts (view in UCSC)
- ENST00000409369 1890 nts (view in UCSC)
- ENST00000450855 587 nts (view in UCSC)
- ENST00000497795 572 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for IL18RAP - Starting at $85 >
- * IL18RAP CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for IL18RAP
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IL18RAP
-
Santa Cruz Biotechnology (SCBT) CRISPR for IL18RAP
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IL18RAP
- Browse OriGene Inhibitory RNA Products For IL18RAP
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Clone products for research
- Applied Biological Materials (abm): Clones for IL18RAP - Starting at $45 >
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- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for IL18RAP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IL18RAP
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: |
Relevant External Links for IL18RAP Gene
- GeneLoc Exon Structure for
- IL18RAP
Expression for IL18RAP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for IL18RAP Gene
This gene is overexpressed in Whole Blood (x43.5).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for IL18RAP
SOURCE GeneReport for Unigene cluster for IL18RAP Gene:
Hs.158315mRNA Expression by UniProt/SwissProt for IL18RAP Gene:
O95256-I18RA_HUMAN
Tissue specificity:
Detected in adrenal gland, bone marrow, brain, fetal brain, fetal liver, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, prostate, salivary gland, skeletal muscle, spinal cord, testis, thymus, thyroid, trachea and uterus (PubMed:17897836). Strongly expressed in peripheral blood leukocytes and spleen and, to a lesser extent, in colon (PubMed:9792649). Specifically coexpressed with IL18R1 in T-helper 1 (Th1)cells (PubMed:10925275, PubMed:11046021, PubMed:10653850).
Evidence on tissue expression from TISSUES for IL18RAP Gene
- Nervous system(4.4)
- Blood(2.6)
- Spleen(2.5)
- Bone marrow(2.4)
- Intestine(2.3)
Primer products for research
-
OriGene qPCR primer pairs for IL18RAP
-
OriGene qPCR primer pairs and template standards for IL18RAP
Gene Expression Assays for research
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for IL18RAP Gene
Orthologs for IL18RAP Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | IL18RAP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | IL18RAP 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | IL18RAP 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Il18rap 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Il18rap 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | IL18RAP 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | IL18RAP 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | IL18RAP 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | IL18RAP 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | il18rap 30 |
|
- Species where no ortholog for IL18RAP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for IL18RAP Gene
- ENSEMBL:
- Gene Tree for IL18RAP (if available)
- TreeFam:
- Gene Tree for IL18RAP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for IL18RAP: view image
Paralogs for IL18RAP Gene
Variants for IL18RAP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for IL18RAP Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11465716 | Benign: not provided. - | 102,445,316(+) |
G/Ap.Val350Ile NM_003853.3(IL18RAP):c.1048G>A (p.Val350Ile) |
MISSENSE | |
| rs201710233 | Likely Benign: not provided | 102,437,250(+) |
C/T NM_003853.3(IL18RAP):c.618C>T (p.Ile206=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
48.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.81;
17.05% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IL18RAP Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL18RAP Gene
Disorders for IL18RAP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| crohn's disease |
|
|
| inflammatory bowel disease |
|
|
| loeffler syndrome |
|
|
| celiac disease 1 |
|
|
Search IL18RAP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for IL18RAP
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for IL18RAP Gene
Publications for IL18RAP Gene
- Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. (PMID: 9792649) Born TL … Sims JE (The Journal of biological chemistry 1998) 2 3 4 23
- Association study of the IL18RAP locus in three European populations with coeliac disease. (PMID: 19103669) Koskinen LL … Saavalainen P (Human molecular genetics 2009) 3 23 41
- Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project. (PMID: 19473509) Grisoni ML … Tregouet DA (BMC medical genetics 2009) 3 23 41
- Association of IL1RL1, IL18R1, and IL18RAP gene cluster polymorphisms with asthma and atopy. (PMID: 18774397) Reijmerink NE … Koppelman GH (The Journal of allergy and clinical immunology 2008) 3 23 41
- Identification of IL-18RAP mRNA truncated splice variants in human testis and the other human tissues. (PMID: 17897836) Fiszer D … Kurpisz M (Cytokine 2007) 3 4 23
ExternalLinks
Products for IL18RAP Gene
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- VectorBuilder Virus packaging for IL18RAP CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for IL18RAP
- antibodies-online: Show 26 available IL18RAP Antibodies ranked by validation data
- Compare Top IL18RAP Antibodies
- antibodies-online: Show 13 available IL18RAP Elisa Kits ranked by validation data
- Compare Top IL18RAP Elisa Kits
- Quality Products:
- antibodies-online: Show 24 available IL18RAP Proteins ranked by validation data
- Compare Top IL18RAP Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for IL18RAP
- Search Santa Cruz Biotechnology (SCBT) for IL18RAP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IL18RAP
- Custom Antibody ServicesProSci Antibodies for IL18RAP
- ProSci Proteins for IL18RAP
- Horizon Cell Lines for IL18RAP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IL18RAP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IL18RAP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for IL18RAP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IL18RAP
Sources for IL18RAP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB