Aliases for IL17D Gene
External Ids for IL17D Gene
Previous GeneCards Identifiers for IL17D Gene
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL17D Gene
IL17D (Interleukin 17D) is a Protein Coding gene. Diseases associated with IL17D include Psoriasis. Among its related pathways are Th17 cell differentiation and Jak-STAT signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17B.
UniProtKB/Swiss-Prot for IL17D Gene
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.