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The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008] See more...
Aliases for IL17C Gene
Aliases for IL17C Gene
External Ids for IL17C Gene
- HGNC: 5983
- Entrez Gene: 27189
- Ensembl: ENSG00000124391
- OMIM: 604628
- UniProtKB: Q9P0M4
Previous GeneCards Identifiers for IL17C Gene
- GC16P080141
- GC16P089673
- GC16P088408
- GC16P088449
- GC16P087232
- GC16P088705
- GC16P074400
Summaries for IL17C Gene
-
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL17C Gene
IL17C (Interleukin 17C) is a Protein Coding gene. Diseases associated with IL17C include Chlorhexidine Allergy and Hyper Ige Syndrome. Among its related pathways are IL-17 Family Signaling Pathways and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17D.
UniProtKB/Swiss-Prot Summary for IL17C Gene
-
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Additional gene information for IL17C Gene
- HGNC(5983)
- Entrez Gene(27189)
- Ensembl(ENSG00000124391)
- OMIM(604628)
- UniProtKB(Q9P0M4)
- Open Targets Platform(ENSG00000124391)
- Search for IL17C at DataMed
- Search for IL17C at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IL17C Gene
Genomics for IL17C Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for IL17C Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH16J088638 | Promoter/Enhancer | 1 | EPDnew ENCODE dbSUPER | 600.7 | -0.1 | -94 | 0.3 | ZBTB33 TCF12 POLR2A ZEB1 ZEB2 EGR1 | IL17C HSALNG0113520 ZC3H18 | |
| GH16J088641 | Enhancer | 0.7 | ENCODE dbSUPER | 600.7 | +1.2 | 1206 | 0.4 | KLF9 MCM3 MCM7 SMAD4 NRF1 ZBTB33 ZNF48 MLLT1 POLR2A | IL17C SNORD68 ENSG00000260121 PIEZO1 RPL13 CYBA lnc-MVD-1 | |
| GH16J088640 | Enhancer | 0.6 | ENCODE dbSUPER | 600.7 | +0.8 | 846 | 0.2 | KLF9 ZNF48 POLR2A GLIS2 | IL17C CYBA lnc-MVD-1 | |
| GH16J088639 | Enhancer | 0.6 | ENCODE dbSUPER | 600.7 | +0.6 | 616 | 0.2 | KLF9 ZBTB10 GLIS2 | IL17C CYBA lnc-MVD-1 | |
| GH16J088596 | Enhancer | 1 | Ensembl ENCODE | 17.4 | -40.4 | -40352 | 4.4 | CEBPG HNRNPL GATAD2A ATF7 PRDM1 TCF12 IKZF2 SP1 CEBPA SOX13 | HSALNG0113518 ZC3H18 IL17C CYBA |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around IL17C on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for IL17C
- Top Transcription factor binding sites by QIAGEN in the IL17C gene promoter:
-
- AhR
- AREB6
- Arnt
- CUTL1
- Gfi-1
- HTF
- MAZR
- p53
- RSRFC4
Genomic Locations for IL17C Gene
Genomic Locations for IL17C Gene
- chr16:88,638,572-88,640,468
- (GRCh38/hg38)
- Size:
- 1,897 bases
- Orientation:
- Plus strand
- chr16:88,704,999-88,706,882
- (GRCh37/hg19)
- Size:
- 1,884 bases
- Orientation:
- Plus strand
Genomic View for IL17C Gene
Genes around IL17C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.2 by HGNC
- 16q24.2 by Entrez Gene
- 16q24.2 by Ensembl
IL17C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IL17C Gene
Proteins for IL17C Gene
-
Protein details for IL17C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P0M4-IL17C_HUMAN
- Recommended name:
- Interleukin-17C
- Protein Accession:
- Q9P0M4
- Q3MIG8
- Q9HC75
Protein attributes for IL17C Gene
- Size:
- 197 amino acids
- Molecular mass:
- 21765 Da
- Quaternary structure:
-
- Binds to a heterodimer formed by IL17RA and IL17RE.
Protein Expression for IL17C Gene
Post-translational modifications for IL17C Gene
No Post-translational modifications
Other Protein References for IL17C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ IL-17C Polyclonal Antibody and Immunotag™ IL17C Antibody
- GeneTex Anti-IL17C antibody
-
Custom Antibody ServicesOriGene Antibodies for IL17C
- Novus Biologicals Antibodies for IL17C
-
Abcam antibodies for IL17C
- Invitrogen Antibodies for IL17C (AFLGC-IL17C)
- antibodies-online: Show 11 available IL17C Antibodies ranked by validation data
- Compare Top IL17C Antibodies
-
Recommended
- 12 IF (p) Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 61 WB Antibodies (anti-human)
- 15 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 IHC (p) Antibodies (anti-human)
- 1 IHC Antibody (anti-human)
- 20 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 8 FACS Antibodies (anti-mouse)
- Sino Biological Antibodies for IL17C
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for IL17C
- Origene Custom Protein Services for IL17C
- Sino Biological Recombinant Proteins for IL17C
- Sino Biological Cell Lysates for IL17C
-
Abcam proteins for IL17C
Assay Products
-
Abcam assays for IL17C
No data available for DME Specific Peptides for IL17C Gene
Domains & Families for IL17C Gene
Gene Families for IL17C Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for IL17C Gene
- InterPro:
- Blocks:
-
- Interleukin-17
- ProtoNet:
Suggested Antigen Peptide Sequences for IL17C Gene
- GenScript: Design optimal peptide antigens:
-
- Cytokine CX2 (IL17C_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9P0M4- Family:
-
- Belongs to the IL-17 family.
Function for IL17C Gene
Molecular function for IL17C Gene
- UniProtKB/Swiss-Prot Function:
- Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by bacterial stimuli, including by lipopolysaccharides (LPS) in gut epithelial cell lines. This up-regulation may be mediated by Toll-like receptors TLR2 and TLR5. Up-regulated by various proinflammatory cytokines, including TNF, IL1B and IL17F. Up-regulation by IL17A in colon epithelial cells has been observed in some cases (PubMed:21993849), but not in others (PubMed:21993848).
- GENATLAS Biochemistry:
- interleukin 17C,not detected in several adult tissues,not in activated T cells,not binding to the IL17 receptor
Phenotypes From GWAS Catalog for IL17C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005125 | cytokine activity | TAS,IEA | -- |
Phenotypes for IL17C Gene
- MGI mutant phenotypes for IL17C:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for IL17C:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- no effect
- Decreased viability
- Decreased vaccinia virus (VACV) infection
- Decreased Salmonella enterica Typhimurium invasion
- Decreased NF-kappaB reporter expression
- Increased S DNA content
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Increased mitotic delay (prometaphase or metaphase alignment problems, MAP), polylobed nuclei, many micronuclei (grape), decreased viability (cell death)
Animal Model Products
-
Taconic Biosciences Mouse Models for IL17C
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for IL17C - Select products 50% OFF >
- * IL17C CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for IL17C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IL17C
-
Santa Cruz Biotechnology (SCBT) CRISPR for IL17C
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IL17C
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Clone Products
- Applied Biological Materials (abm): Clones for IL17C - Select products 50% OFF >
- * IL17C as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for IL17C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IL17C
Cell Line Products
-
Horizon Cell Lines for IL17C
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for IL17C Gene
Localization for IL17C Gene
Subcellular locations from UniProtKB/Swiss-Prot for IL17C Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 2 |
| nucleus | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | TAS,IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IL17C Gene
Pathways & Interactions for IL17C Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL-17 Family Signaling Pathways | ||
| 2 | Cytokine Signaling in Immune system | ||
| 3 | PEDF Induced Signaling | ||
| 4 | Innate Immune System |
.61
|
|
Pathways by source for IL17C Gene
1 BioSystems pathway for IL17C Gene
4 Reactome pathways for IL17C Gene
2 KEGG pathways for IL17C Gene
1 R&D Systems pathway for IL17C Gene
Interacting Proteins for IL17C Gene
GPS-Prot Interaction Network for IL17C
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006954 | inflammatory response | TAS,IEA | -- |
| GO:0007166 | cell surface receptor signaling pathway | TAS | 10639155 |
| GO:0007267 | cell-cell signaling | TAS | 10639155 |
| GO:0097400 | interleukin-17-mediated signaling pathway | TAS | -- |
No data available for SIGNOR curated interactions for IL17C Gene
Transcripts for IL17C Gene
mRNA/cDNA for IL17C Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000244241 1060 nts (view in UCSC)
- ENST00000569133 1028 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for IL17C - Select products 50% OFF >
- * IL17C CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for IL17C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IL17C
-
Santa Cruz Biotechnology (SCBT) CRISPR for IL17C
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IL17C
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Clone Products
- Applied Biological Materials (abm): Clones for IL17C - Select products 50% OFF >
- * IL17C as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for IL17C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IL17C
Relevant External Links for IL17C Gene
- GeneLoc Exon Structure for
- IL17C
Expression for IL17C Gene
mRNA differential expression in normal tissues according to GTEx for IL17C Gene
This gene is overexpressed in Testis (x5.6), Stomach (x5.3), and Whole Blood (x4.3).
This gene is overexpressed in Islet of Langerhans (64.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IL17C Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for IL17C
SOURCE GeneReport for Unigene cluster for IL17C Gene:
Hs.278911Evidence on tissue expression from TISSUES for IL17C Gene
- Lung(4.4)
- Intestine(2.5)
- Blood(2.3)
- Lymph node(2.3)
- Skin(2.2)
- Spleen(2)
Primer Products
-
OriGene qPCR primer pairs for IL17C
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IL17C Gene
Orthologs for IL17C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | IL17C 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | IL17C 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | IL17C 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Il17c 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Il17c 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | IL17C 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | IL17C 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | IL17C 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | IL17C 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | il17c 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | il17c 31 |
|
OneToOne |
- Species where no ortholog for IL17C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for IL17C Gene
- ENSEMBL:
- Gene Tree for IL17C (if available)
- TreeFam:
- Gene Tree for IL17C (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for IL17C: view image
Paralogs for IL17C Gene
Variants for IL17C Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for IL17C Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 764104 | Likely Benign: not provided | 88,639,809(+) | C/T | INTRON_VARIANT | |
| 782896 | Likely Benign: not provided | 88,639,977(+) | G/A | MISSENSE_VARIANT | |
| 786947 | Benign: not provided | 88,640,066(+) | A/G | SYNONYMOUS_VARIANT | |
| 790169 | Benign: not provided | 88,639,068(+) | G/A | MISSENSE_VARIANT | |
| rs11465492 | - | p.Arg25Gly |
Residual Variation Intolerance Score:
50.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.22;
24.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IL17C Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IL17C
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL17C Gene
Disorders for IL17C Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chlorhexidine allergy |
|
|
| hyper ige syndrome |
|
|
| systemic lupus erythematosus |
|
|
| amyotrophic lateral sclerosis 1 |
|
|
Search IL17C in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for IL17C
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for IL17C Gene
Publications for IL17C Gene
- Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family. (PMID: 10639155) Li H … Wood WI (Proceedings of the National Academy of Sciences of the United States of America 2000) 2 3 4 23
- IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. (PMID: 21993848) Ramirez-Carrozzi V … Pappu R (Nature immunology 2011) 3 4
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 41
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S … Kang D (Human immunology 2010) 3 41
ExternalLinks
Products for IL17C Gene
- View all 24 R&D Systems IL17C (IL-17C) Products
- View all 2 R&D Systems IL17C (IL-17C) Proteins and Enzymes
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- Custom Antibody ServicesOriGene Antibodies for IL17C
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- Taconic Biosciences Mouse Models for IL17C
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for IL17C (AFLGC-IL17C)
- VectorBuilder Custom and pre-made DNA vectors for IL17C (ie. gene expression, shRNA knockdown, CRISPR)
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- VectorBuilder Virus packaging for IL17C CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for IL17C
- antibodies-online: Show 11 available IL17C Antibodies ranked by validation data
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- Recommended
- 12 IF (p) Antibodies (anti-rat)
- 11 WB Antibodies (anti-rat)
- 61 WB Antibodies (anti-human)
- 15 FACS Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 IHC (p) Antibodies (anti-human)
- 1 IHC Antibody (anti-human)
- 20 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 8 FACS Antibodies (anti-mouse)
- antibodies-online: Show 27 available IL17C Elisa Kits ranked by validation data
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- antibodies-online: Show 14 available IL17C Proteins ranked by validation data
- Compare Top IL17C Proteins
- Horizon Cell Lines for IL17C
- Browse GeneCopoeia Cell Lines
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IL17C
Sources for IL17C Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB