Aliases for IL17B Gene
External Ids for IL17B Gene
Previous GeneCards Identifiers for IL17B Gene
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]
GeneCards Summary for IL17B Gene
IL17B (Interleukin 17B) is a Protein Coding gene. Diseases associated with IL17B include Leiomyoma and Keratoconus 1. Among its related pathways are IL-17 Family Signaling Pathways and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17D.
UniProtKB/Swiss-Prot Summary for IL17B Gene
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.