The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attribute... See more...

Aliases for IL16 Gene

Aliases for IL16 Gene

  • Interleukin 16 2 3 5
  • Lymphocyte Chemoattractant Factor 2 3
  • Pro-Interleukin-16 3 4
  • Prointerleukin 16 2 3
  • Interleukin 16 (Lymphocyte Chemoattractant Factor) 2
  • Neuronal Interleukin 16 3
  • PrIL-16 3
  • PRIL16 3
  • NIL16 3
  • LCF 3

External Ids for IL16 Gene

Previous GeneCards Identifiers for IL16 Gene

  • GC15P077545
  • GC15P074632
  • GC15P079051
  • GC15P079190
  • GC15P079262
  • GC15P079276
  • GC15P081489
  • GC15P058247

Summaries for IL16 Gene

Entrez Gene Summary for IL16 Gene

  • The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

GeneCards Summary for IL16 Gene

IL16 (Interleukin 16) is a Protein Coding gene. Diseases associated with IL16 include Whipple Disease and Cd4/Cd8 T-Cell Ratio. Among its related pathways are ERK Signaling and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is PDZD2.

UniProtKB/Swiss-Prot Summary for IL16 Gene

  • Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
  • Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.
  • Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Gene Wiki entry for IL16 Gene

Additional gene information for IL16 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IL16 Gene

Genomics for IL16 Gene

GeneHancer (GH) Regulatory Elements for IL16 Gene

Promoters and enhancers for IL16 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J081291 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 510.9 +138.8 138807 14.7 ZBTB40 ZNF217 SIN3A USF1 SP1 EP300 REST JUND CTCF RFX1 IL16 piR-53038 piR-59520 TLNRD1 STARD5 TMC3 ENSG00000271725 piR-46911
GH15J081160 Enhancer 0.9 Ensembl ENCODE CraniofacialAtlas 500.7 +1.7 1726 2.2 MXI1 NFIC ZNF263 ZBTB48 FOXP2 KLF17 SCRT1 RCOR1 NFIB ESRRA IL16 lnc-IL16-6 piR-33422-157 piR-39099-108 5MWI_A-058
GH15J081157 Enhancer 0.6 Ensembl ENCODE 500.7 -1.9 -1875 1 FOS ZNF664 CEBPB MYC IL16 lnc-IL16-6 piR-31470-200 piR-39099-108 piR-58297-184 lnc-MESD-6
GH15J081913 Enhancer 1 Ensembl ENCODE CraniofacialAtlas 10.5 +755.3 755267 3 ZIC2 MXI1 RBM25 ZNF266 POLR2A NR2F2 JUND BCOR ZBTB48 RCOR1 WHAMM IL16 piR-32023-089 piR-51137-045 LOC102724001 ENSG00000259692
GH15J081274 Enhancer 1.1 Ensembl ENCODE dbSUPER 6.3 +116.0 116025 2.4 HNRNPK ZNF217 CTCF REST RAD21 MYC TRIM22 SMC3 SIN3A TCF12 IL16 lnc-STARD5-2 5MWI_A-058
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around IL16 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for IL16

Top Transcription factor binding sites by QIAGEN in the IL16 gene promoter:
  • E47
  • Pax-4a
  • STAT1
  • STAT1alpha
  • STAT1beta
  • Tal-1beta
  • USF-1
  • USF-1:USF-2
  • USF1
  • USF2

Genomic Locations for IL16 Gene

Genomic Locations for IL16 Gene
chr15:81,159,575-81,314,058
(GRCh38/hg38)
Size:
154,484 bases
Orientation:
Plus strand
chr15:81,451,916-81,605,104
(GRCh37/hg19)
Size:
153,189 bases
Orientation:
Plus strand

Genomic View for IL16 Gene

Genes around IL16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IL16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IL16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IL16 Gene

Proteins for IL16 Gene

  • Protein details for IL16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14005-IL16_HUMAN
    Recommended name:
    Pro-interleukin-16
    Protein Accession:
    Q14005
    Secondary Accessions:
    • A6NM20
    • A8MU65
    • B5TY35
    • B9EGR6
    • H3BVH5
    • Q16435
    • Q6VVE6
    • Q6ZMQ7
    • Q9UP18

    Protein attributes for IL16 Gene

    Size:
    1332 amino acids
    Molecular mass:
    141752 Da
    Quaternary structure:
    • Homotetramer (Probable). According to PubMed:9699630, the formation of a homotetrameric protein complex is not required for the chemo-attractant function. Isoform 3 interacts (via PDZ 3 domain) with PPP1R12A, PPP1R12B and PPP1R12C. Isoform 1 interacts with PPP1R12B. Isoform 3 interacts with GRIN2A. Isoform 3 interacts with GABPB1. Isoform 3 interacts (via PDZ 3 domain) with HDAC3. Isoform 1 interacts with GRIN2D, KCNJ10, KCNJ15 and CACNA1C (By similarity).
    • (Microbial infection) Isoform 3 interacts with HTLV-1 tax.
    Miscellaneous:
    • [Isoform 1]: Produced by alternative promoter usage. Is probably proteolytically processed to yield IL-16.
    • [Isoform 2]: Produced by alternative splicing of isoform 1. Is probably proteolytically processed to yield IL-16.
    • [Isoform 3]: Produced by alternative promoter usage. Is proteolytically processed to yield IL-16.

    Three dimensional structures from OCA and Proteopedia for IL16 Gene

    Alternative splice isoforms for IL16 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IL16 Gene

Post-translational modifications for IL16 Gene

  • Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for IL16 Gene

Domains & Families for IL16 Gene

Gene Families for IL16 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for IL16 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IL16 Gene

GenScript: Design optimal peptide antigens:
  • Interleukin 16 (B5TY35_HUMAN)
  • Pro-interleukin-16 (IL16_HUMAN)
  • IL16 protein (Q05BE6_HUMAN)
  • IL16 protein (Q8IUU6_HUMAN)
genes like me logo Genes that share domains with IL16: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for IL16 Gene

Function for IL16 Gene

Molecular function for IL16 Gene

UniProtKB/Swiss-Prot Function:
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
UniProtKB/Swiss-Prot Function:
Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.
UniProtKB/Swiss-Prot Function:
Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
UniProtKB/Swiss-Prot Induction:
Isoform 3 is down-regulated in T-cells after TCR activation.
GENATLAS Biochemistry:
interleukin 16,T cell derived cytokine,lymphocyte chemoattractant factor,inducing the chemotactic and immunomodulatory responses of ED4+ lymphocytes monocytes and eosinophils

Phenotypes From GWAS Catalog for IL16 Gene

Gene Ontology (GO) - Molecular Function for IL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005125 cytokine activity IBA 21873635
GO:0005515 protein binding IEA --
GO:0042609 CD4 receptor binding IPI,IBA 24942581
genes like me logo Genes that share ontologies with IL16: view
genes like me logo Genes that share phenotypes with IL16: view

Animal Models for IL16 Gene

MGI Knock Outs for IL16:
  • Il16 Il16<tm1Korn>

Animal Model Products

  • Taconic Biosciences Mouse Models for IL16

CRISPR Products

miRNA for IL16 Gene

miRTarBase miRNAs that target IL16

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IL16 Gene

Localization for IL16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for IL16 Gene

[Interleukin-16]: Secreted.
[Isoform 1]: Cytoplasm.
[Isoform 3]: Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IL16 gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 5
cytosol 5
cytoskeleton 2
mitochondrion 2
lysosome 2
peroxisome 1
endoplasmic reticulum 1
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (4)
  • Cytosol (2)
  • Midbody ring (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for IL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA,TAS --
GO:0005615 extracellular space IEA --
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA,TAS --
genes like me logo Genes that share ontologies with IL16: view

Pathways & Interactions for IL16 Gene

PathCards logo

SuperPathways for IL16 Gene

SuperPathway Contained pathways
1 PEDF Induced Signaling
.94
.94
.73
.71
.62
.61
.57
.51
.47
.46
.43
2 TGF-Beta Pathway
.60
.60
.57
.43
.40
3 Akt Signaling
.60
.60
.55
4 ERK Signaling
.61
.61
.51
5 PAK Pathway
.56
.56
genes like me logo Genes that share pathways with IL16: view

Pathways by source for IL16 Gene

25 Qiagen pathways for IL16 Gene
  • Akt Signaling
  • all-trans-Retinoic Acid Signaling in Brain
  • Antioxidant Action of Vitamin-C
  • Cytokine Network
  • Endothelin-1 Signaling Pathway

SIGNOR curated interactions for IL16 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for IL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006935 chemotaxis IEA --
GO:0006955 immune response TAS 9144227
GO:0007165 signal transduction IEA --
GO:0016032 viral process IEA --
GO:0019221 cytokine-mediated signaling pathway TAS --
genes like me logo Genes that share ontologies with IL16: view

Drugs & Compounds for IL16 Gene

(13) Drugs for IL16 Gene - From: PharmGKB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Platinum compounds Pharma 0

(6) Additional Compounds for IL16 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with IL16: view

Transcripts for IL16 Gene

mRNA/cDNA for IL16 Gene

6 REFSEQ mRNAs :
23 NCBI additional mRNA sequence :
13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IL16 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c · 14d · 14e · 14f ^ 15 ^ 16a · 16b · 16c ^
SP1: - - -
SP2: - -
SP3:
SP4:
SP5:
SP6:
SP7: -
SP8: -
SP9:
SP10:
SP11:
SP12:

ExUns: 17a · 17b · 17c · 17d · 17e ^ 18 ^ 19 ^ 20a · 20b · 20c ^ 21a · 21b ^ 22a · 22b · 22c ^ 23a · 23b · 23c
SP1:
SP2:
SP3: - -
SP4: -
SP5: - -
SP6: -
SP7: -
SP8:
SP9:
SP10: - -
SP11:
SP12:

Relevant External Links for IL16 Gene

GeneLoc Exon Structure for
IL16

Expression for IL16 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IL16 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IL16 Gene

This gene is overexpressed in Whole Blood (x10.2), Brain - Cerebellar Hemisphere (x4.5), and Brain - Cerebellum (x4.3).

Protein differential expression in normal tissues from HIPED for IL16 Gene

This gene is overexpressed in Lymph node (24.4), CD8 Tcells (11.4), Tlymphocyte (9.7), and Peripheral blood mononuclear cells (8.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for IL16 Gene



Protein tissue co-expression partners for IL16 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for IL16

SOURCE GeneReport for Unigene cluster for IL16 Gene:

Hs.459095

mRNA Expression by UniProt/SwissProt for IL16 Gene:

Q14005-IL16_HUMAN
Tissue specificity: Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.

Evidence on tissue expression from TISSUES for IL16 Gene

  • Blood(4.7)
  • Nervous system(4.6)
  • Liver(4.3)
  • Lymph node(2.7)
  • Spleen(2.7)
  • Lung(2.3)
  • Intestine(2.2)
  • Bone marrow(2.1)
genes like me logo Genes that share expression patterns with IL16: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for IL16 Gene

Orthologs for IL16 Gene

This gene was present in the common ancestor of animals.

Orthologs for IL16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IL16 31 30
  • 99.35 (n)
OneToOne
dog
(Canis familiaris)
Mammalia IL16 31 30
  • 83.26 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Il16 17 31 30
  • 82.13 (n)
rat
(Rattus norvegicus)
Mammalia Il16 30
  • 82.08 (n)
cow
(Bos Taurus)
Mammalia IL16 31 30
  • 82.02 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IL16 31
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IL16 31
  • 6 (a)
OneToOne
chicken
(Gallus gallus)
Aves IL16 31 30
  • 60.93 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-5402 31
  • 50 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia il16 30
  • 56.5 (n)
zebrafish
(Danio rerio)
Actinopterygii CABZ01068274.1 31
  • 34 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta bbg 31
  • 10 (a)
OneToOne
Species where no ortholog for IL16 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IL16 Gene

ENSEMBL:
Gene Tree for IL16 (if available)
TreeFam:
Gene Tree for IL16 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for IL16: view image

Paralogs for IL16 Gene

Paralogs for IL16 Gene

(9) SIMAP similar genes for IL16 Gene using alignment to 11 proteins:

  • IL16_HUMAN
  • B5TY35_HUMAN
  • H0YKB7_HUMAN
  • H0YLB1_HUMAN
  • H0YLH9_HUMAN
  • H0YLL1_HUMAN
  • H3BN12_HUMAN
  • H3BT15_HUMAN
  • H3BVH5_HUMAN
  • Q05BE6_HUMAN
  • Q8IUU6_HUMAN
genes like me logo Genes that share paralogs with IL16: view

Variants for IL16 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for IL16 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
713502 Benign: not provided 81,300,079(+) G/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
717458 Benign: not provided 81,300,140(+) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
752464 Likely Benign: not provided 81,299,918(+) C/G NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
758096 Benign: not provided 81,305,931(+) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
770624 Benign: not provided 81,300,405(+) T/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for IL16 Gene

Structural Variations from Database of Genomic Variants (DGV) for IL16 Gene

Variant ID Type Subtype PubMed ID
esv3581786 CNV loss 25503493
nsv1040767 CNV loss 25217958
nsv1048788 CNV loss 25217958
nsv570236 CNV loss 21841781
nsv952009 CNV duplication 24416366
nsv974611 CNV duplication 23825009

Variation tolerance for IL16 Gene

Residual Variation Intolerance Score: 39.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.19; 87.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IL16 Gene

Human Gene Mutation Database (HGMD)
IL16
SNPedia medical, phenotypic, and genealogical associations of SNPs for
IL16

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IL16 Gene

Disorders for IL16 Gene

MalaCards: The human disease database

(26) MalaCards diseases for IL16 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
whipple disease
  • intestinal lipodystrophy
cd4/cd8 t-cell ratio
graves' disease
  • toxic diffuse goiter
allergic asthma
  • atopic asthma
viral meningitis
  • meningitis viral
- elite association - COSMIC cancer census association via MalaCards
Search IL16 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for IL16

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with IL16: view

No data available for UniProtKB/Swiss-Prot and Genatlas for IL16 Gene

Publications for IL16 Gene

  1. Genetic polymorphism of interleukin-16 and risk of nasopharyngeal carcinoma. (PMID: 19758567) Gao LB … Zhang L (Clinica chimica acta; international journal of clinical chemistry 2009) 3 23 41 54
  2. The association of interleukin-16 polymorphisms with IL-16 serum levels and risk of colorectal and gastric cancer. (PMID: 19073878) Gao LB … Zhang L (Carcinogenesis 2009) 3 23 41 54
  3. Association of the interleukin (IL)-16 gene polymorphisms with Graves' disease. (PMID: 18394967) Gu XJ … Zhao YJ (Clinical immunology (Orlando, Fla.) 2008) 3 23 41 54
  4. Association between the polymorphisms of IL-4 gene promoter (-590C>T), IL-13 coding region (R130Q) and IL-16 gene promoter (-295T>C) and allergic asthma. (PMID: 17303923) Hosseini-Farahabadi S … Khaje Daluei M (Iranian journal of allergy, asthma, and immunology 2007) 3 23 41 54
  5. Association of asthma with a functional promoter polymorphism in the IL16 gene. (PMID: 16387589) Burkart KM … O'Connor GT (The Journal of allergy and clinical immunology 2006) 3 23 41 54

Products for IL16 Gene

Sources for IL16 Gene