Aliases for IL13RA2 Gene
External Ids for IL13RA2 Gene
Previous GeneCards Identifiers for IL13RA2 Gene
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
GeneCards Summary for IL13RA2 Gene
IL13RA2 (Interleukin 13 Receptor Subunit Alpha 2) is a Protein Coding gene. Diseases associated with IL13RA2 include Glioblastoma and Idiopathic Interstitial Pneumonia. Among its related pathways are IL4-mediated signaling events and Akt Signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and cytokine receptor activity. An important paralog of this gene is PRLR.
UniProtKB/Swiss-Prot Summary for IL13RA2 Gene
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).