Aliases for IGSF5 Gene
External Ids for IGSF5 Gene
Previous GeneCards Identifiers for IGSF5 Gene
GeneCards Summary for IGSF5 Gene
IGSF5 (Immunoglobulin Superfamily Member 5) is a Protein Coding gene. Among its related pathways are Tight junction and Insulin receptor recycling. Gene Ontology (GO) annotations related to this gene include PDZ domain binding. An important paralog of this gene is IGLON5.
UniProtKB/Swiss-Prot Summary for IGSF5 Gene
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).