Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IGLV2-33 Gene

Aliases for IGLV2-33 Gene

  • Immunoglobulin Lambda Variable 2-33 (Non-Functional) 2 3 5 13
  • Immunoglobulin Lambda Variable 2-33 2
  • IGLV233 3
  • V1-9 3

External Ids for IGLV2-33 Gene

Previous GeneCards Identifiers for IGLV2-33 Gene

  • GC22U990163
  • GC22P021255
  • GC22P021262
  • GC22P022930

Summaries for IGLV2-33 Gene

GeneCards Summary for IGLV2-33 Gene

IGLV2-33 (Immunoglobulin Lambda Variable 2-33 (Non-Functional)) is a Protein Coding gene. An important paralog of this gene is IGLV2-18.

Additional gene information for IGLV2-33 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLV2-33 Gene

Genomics for IGLV2-33 Gene

GeneHancer (GH) Regulatory Elements for IGLV2-33 Gene

Promoters and enhancers for IGLV2-33 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J022586 Promoter 1.2 Ensembl 600.7 -1.5 -1454 0.6 CC2D1A CBFA2T2 MLLT1 SP7 RAD21 SMARCA4 MTA1 ARID2 DPF2 RNF2 IGLV2-33 TOP3B IGLV5-52 PPIL2 ENSG00000234630 ENSG00000272779 PRAME LL22NC03-63E9.3 IGLV2-28 IGLV3-27
GH22J022587 Enhancer 0.9 ENCODE 600.7 -1.1 -1050 0.2 CC2D1A CTCF CBFA2T2 SP7 RAD21 SMARCA4 MTA1 ARID2 DPF2 PHF21A IGLV2-33 IGLV5-52 TOP3B PPIL2 PRAME LL22NC03-63E9.3 IGLV2-28 IGLV3-27 ENSG00000225544 ENSG00000234630
GH22J022589 Enhancer 0.3 Ensembl 600.7 +1.1 1146 0.2 TARDBP IGLV2-33 LL22NC03-63E9.3 PRAME IGLV3-27 IGLV2-28 POM121L1P IGLV3-32 IGL
GH22J022594 Enhancer 0.9 Ensembl ENCODE 0.4 +6.0 5987 0.7 CTCF GTF2F1 RAD21 HNRNPUL1 ZNF143 ZSCAN4 TRIM22 ZNF561 SNRNP70 LEF1 IGLV3-32 TOP3B IGLV5-52 PPIL2 ENSG00000234630 IGLV2-28 IGLV3-27 ENSG00000225544 IGLV2-33 IGL
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around IGLV2-33 on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGLV2-33 Gene

Genomic Locations for IGLV2-33 Gene
chr22:22,588,155-22,588,688
(GRCh38/hg38)
Size:
534 bases
Orientation:
Plus strand
chr22:22,930,626-22,931,159
(GRCh37/hg19)
Size:
534 bases
Orientation:
Plus strand

Genomic View for IGLV2-33 Gene

Genes around IGLV2-33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGLV2-33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGLV2-33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGLV2-33 Gene

Proteins for IGLV2-33 Gene

  • Protein details for IGLV2-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6J2-A0A075B6J2_HUMAN
    Recommended name:
    Immunoglobulin lambda variable 2-33 (non-functional)
    Protein Accession:
    A0A075B6J2

    Protein attributes for IGLV2-33 Gene

    Size:
    118 amino acids
    Molecular mass:
    12686 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGLV2-33 Gene

Post-translational modifications for IGLV2-33 Gene

No Post-translational modifications

Other Protein References for IGLV2-33 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGLV2-33 Gene

Domains & Families for IGLV2-33 Gene

Gene Families for IGLV2-33 Gene

Protein Domains for IGLV2-33 Gene

Suggested Antigen Peptide Sequences for IGLV2-33 Gene

GenScript: Design optimal peptide antigens:
  • V1-9 protein (Q5NV66_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGLV2-33: view

No data available for UniProtKB/Swiss-Prot for IGLV2-33 Gene

Function for IGLV2-33 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLV2-33 Gene

Localization for IGLV2-33 Gene

Gene Ontology (GO) - Cellular Components for IGLV2-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA --
genes like me logo Genes that share ontologies with IGLV2-33: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for IGLV2-33 Gene

Pathways & Interactions for IGLV2-33 Gene

PathCards logo

SuperPathways for IGLV2-33 Gene

No Data Available

Interacting Proteins for IGLV2-33 Gene

Gene Ontology (GO) - Biological Process for IGLV2-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response IBA --
genes like me logo Genes that share ontologies with IGLV2-33: view

No data available for Pathways by source and SIGNOR curated interactions for IGLV2-33 Gene

Drugs & Compounds for IGLV2-33 Gene

No Compound Related Data Available

Transcripts for IGLV2-33 Gene

mRNA/cDNA for IGLV2-33 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGLV2-33 Gene

No ASD Table

Relevant External Links for IGLV2-33 Gene

GeneLoc Exon Structure for
IGLV2-33
ECgene alternative splicing isoforms for
IGLV2-33

Expression for IGLV2-33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGLV2-33 Gene

genes like me logo Genes that share expression patterns with IGLV2-33: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGLV2-33 Gene

Orthologs for IGLV2-33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGLV2-33 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 35
  • 59 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 41 (a)
OneToMany
Species where no ortholog for IGLV2-33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGLV2-33 Gene

ENSEMBL:
Gene Tree for IGLV2-33 (if available)
TreeFam:
Gene Tree for IGLV2-33 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for IGLV2-33: view image

Paralogs for IGLV2-33 Gene

genes like me logo Genes that share paralogs with IGLV2-33: view

Variants for IGLV2-33 Gene

Additional Variant Information for IGLV2-33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGLV2-33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGLV2-33 Gene

Disorders for IGLV2-33 Gene

No disorders were found for IGLV2-33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGLV2-33 Gene

Publications for IGLV2-33 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S … Sun P (Molecular immunology 2002) 3 58
  2. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 13 58
  3. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PMID: 9074928) Kawasaki K … Shimizu N (Genome research 1997) 3 58
  4. Sequence and evolution of the human germline V lambda repertoire. (PMID: 8951372) Williams SC … Winter G (Journal of molecular biology 1996) 3 58
  5. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi RJ … Cooper NR (Journal of immunology (Baltimore, Md. : 1950) 1976) 3 58

Products for IGLV2-33 Gene

Sources for IGLV2-33 Gene

Content
Loading form....