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Aliases for IGLJ Gene

Aliases for IGLJ Gene

  • Immunoglobulin Lambda Joining Cluster 3
  • Immunoglobulin Lambda Joining Group 3
  • J Region Of Lambda Light Chains 3
  • IGLJ@ 3

External Ids for IGLJ Gene

Summaries for IGLJ Gene

Entrez Gene Summary for IGLJ Gene

  • Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains (see MIM 147100) and 2 identical light chains, either kappa (see MIM 147200) or lambda, joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. The kappa and lambda light chains have no apparent functional differences. Each Ig lambda light chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by a C region gene (IGLC1; MIM 147220), that provides signaling functions. The lambda light chain V region is encoded by 2 types of genes: V genes (see MIM 147240) and joining (J) genes. Random selection of just 1 gene of each type to assemble a V region accounts for the great diversity of V regions among Ig molecules. The lambda light chain locus on chromosome 22 contains approximately 30 functional V genes, followed by approximately 4 functional J genes. Due to polymorphism, the numbers of functional V and J genes differ among individuals (Janeway et al., 2005).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGLJ Gene

IGLJ (Immunoglobulin Lambda Joining Cluster) is a Genetic Locus. Among its related pathways are Immune response Fc epsilon RI pathway and Immune response Lectin induced complement pathway.

Additional gene information for IGLJ Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLJ Gene

Genomics for IGLJ Gene

Genomic Locations for IGLJ Gene

Genomic Locations for IGLJ Gene
Unknown strand

Genomic View for IGLJ Gene

Cytogenetic band:
GeneLoc Logo Gene Density

No data available for GeneHancer (GH) Regulatory Elements and RefSeq DNA sequence for IGLJ Gene

Function for IGLJ Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLJ Gene

Localization for IGLJ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IGLJ Gene

Drugs & Compounds for IGLJ Gene

No Compound Related Data Available

Transcripts for IGLJ Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGLJ Gene

No ASD Table

No data available for mRNA/cDNA for IGLJ Gene

Expression for IGLJ Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGLJ Gene

Orthologs for IGLJ Gene

No data available for Orthologs and Evolution for IGLJ Gene

Paralogs for IGLJ Gene

No data available for Paralogs for IGLJ Gene

Variants for IGLJ Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for IGLJ Gene

Disorders for IGLJ Gene

No disorders were found for IGLJ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGLJ Gene

Publications for IGLJ Gene

No publications were found for IGLJ Gene.

Products for IGLJ Gene

Sources for IGLJ Gene

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