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Aliases for IGK Gene

Aliases for IGK Gene

  • Immunoglobulin Kappa Locus 2 3
  • IGK@ 3

External Ids for IGK Gene

Previous HGNC Symbols for IGK Gene

  • IGK@

Previous GeneCards Identifiers for IGK Gene

  • GC02P089931
  • GC02P090039

Summaries for IGK Gene

GeneCards Summary for IGK Gene

IGK (Immunoglobulin Kappa Locus) is a Protein Coding gene. Among its related pathways are Immune response Fc epsilon RI pathway and Development IGF-1 receptor signaling.

Gene Wiki entry for IGK Gene

Additional gene information for IGK Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGK Gene

Genomics for IGK Gene

GeneHancer (GH) Regulatory Elements for IGK Gene

Promoters and enhancers for IGK Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J089909 Enhancer 0.5 Ensembl 0.2 +57.8 57789 0.5 CTCF SRF ZNF654 SMC3 ELF1 RAD21 IGKV3D-34 IGKV1D-33 IGK
GH02J090100 Promoter 0.5 EPDnew 0.1 +248.5 248464 0.1 IGKV1D-16 GC02M090100 IGK
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around IGK on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGK Gene

Genomic Locations for IGK Gene
383,611 bases
Plus strand
383,668 bases
Plus strand

Genomic View for IGK Gene

Genes around IGK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGK Gene

Proteins for IGK Gene

Post-translational modifications for IGK Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGK Gene

Domains & Families for IGK Gene

Gene Families for IGK Gene

Suggested Antigen Peptide Sequences for IGK Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGK: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for IGK Gene

Function for IGK Gene

Phenotypes From GWAS Catalog for IGK Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGK Gene

Localization for IGK Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IGK Gene

Drugs & Compounds for IGK Gene

No Compound Related Data Available

Transcripts for IGK Gene

mRNA/cDNA for IGK Gene

(859) Additional mRNA sequences :

Unigene Clusters for IGK Gene

Immunoglobulin kappa locus:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IGK Gene

No ASD Table

Relevant External Links for IGK Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGK Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGK Gene

NURSA nuclear receptor signaling pathways regulating expression of IGK Gene:


SOURCE GeneReport for Unigene cluster for IGK Gene:

genes like me logo Genes that share expression patterns with IGK: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGK Gene

Orthologs for IGK Gene

No data available for Orthologs and Evolution for IGK Gene

Paralogs for IGK Gene

No data available for Paralogs for IGK Gene

Variants for IGK Gene

Additional Variant Information for IGK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGK Gene

Disorders for IGK Gene

No disorders were found for IGK Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGK Gene

Publications for IGK Gene

  1. Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia. (PMID: 16622520) Belessi C … Laoutaris N (Molecular medicine (Cambridge, Mass.) 2005) 3 22 58
  2. IGK with conserved IGΚV/IGΚJ repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration. (PMID: 26429876) Wang C … Yin CC (Oncotarget 2015) 3 58
  3. Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus. (PMID: 25700344) Hehle V … Spencer J (Molecular immunology 2015) 3 58
  4. Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. (PMID: 25149546) Hutchinson AT … Raison RL (Human immunology 2014) 3 58
  5. Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody. (PMID: 24598740) Ponomarenko N … Gabibov A (Acta crystallographica. Section D, Biological crystallography 2014) 3 58

Products for IGK Gene

Sources for IGK Gene

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