Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IGHV4OR15-8 Gene

Aliases for IGHV4OR15-8 Gene

  • Immunoglobulin Heavy Variable 4/OR15-8 (Non-Functional) 2 3 5
  • V-Set And Immunoglobulin Domain Containing 6 2 3
  • Immunoglobulin Heavy Variable 4/OR15-8 2
  • IGHV4/OR15-8 3
  • IGHV4OR158 3
  • VSIG6 3

External Ids for IGHV4OR15-8 Gene

Previous HGNC Symbols for IGHV4OR15-8 Gene

  • VSIG6

Previous GeneCards Identifiers for IGHV4OR15-8 Gene

  • GC15U990084
  • GC15M022473
  • GC15M022486

Summaries for IGHV4OR15-8 Gene

GeneCards Summary for IGHV4OR15-8 Gene

IGHV4OR15-8 (Immunoglobulin Heavy Variable 4/OR15-8 (Non-Functional)) is a Protein Coding gene. An important paralog of this gene is LOC102724971.

Additional gene information for IGHV4OR15-8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV4OR15-8 Gene

Genomics for IGHV4OR15-8 Gene

GeneHancer (GH) Regulatory Elements for IGHV4OR15-8 Gene

Promoters and enhancers for IGHV4OR15-8 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I022184 Enhancer 0.7 ENCODE dbSUPER 550.8 +0.5 537 0.2 CTCF RB1 NR2F1 ZBTB33 RAD21 CREM GC15M022187 IGHV4OR15-8 LOC642131 IGHV1OR15-1
GH15I022186 Enhancer 0.6 ENCODE dbSUPER 550.8 +0.3 277 0.2 CTCF RB1 ZBTB33 GC15M022187 IGHV4OR15-8 LOC642131 IGHV1OR15-1
GH15I022182 Enhancer 0.5 dbSUPER 550.8 +1.9 1853 1.4 ZNF316 MAFG NFE2 EMSY NFE2L2 GC15M022187 IGHV4OR15-8 LOC642131 IGHV1OR15-1
GH15I022185 Enhancer 0.3 dbSUPER 550.8 -1.6 -1638 2.8 SREBF1 GC15M022187 IGHV4OR15-8 LOC642131 IGHV1OR15-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IGHV4OR15-8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGHV4OR15-8 Gene

Genomic Locations for IGHV4OR15-8 Gene
436 bases
Minus strand

Genomic View for IGHV4OR15-8 Gene

Genes around IGHV4OR15-8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV4OR15-8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV4OR15-8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for IGHV4OR15-8 Gene

Proteins for IGHV4OR15-8 Gene

  • Protein details for IGHV4OR15-8 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Immunoglobulin heavy variable 4/OR15-8 (non-functional)
    Protein Accession:

    Protein attributes for IGHV4OR15-8 Gene

    117 amino acids
    Molecular mass:
    12999 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV4OR15-8 Gene

Post-translational modifications for IGHV4OR15-8 Gene

No Post-translational modifications

Other Protein References for IGHV4OR15-8 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV4OR15-8 Gene

Domains & Families for IGHV4OR15-8 Gene

Gene Families for IGHV4OR15-8 Gene

Protein Domains for IGHV4OR15-8 Gene

Suggested Antigen Peptide Sequences for IGHV4OR15-8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV4OR15-8: view

No data available for UniProtKB/Swiss-Prot for IGHV4OR15-8 Gene

Function for IGHV4OR15-8 Gene

genes like me logo Genes that share phenotypes with IGHV4OR15-8: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV4OR15-8 Gene

Localization for IGHV4OR15-8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IGHV4OR15-8 Gene

Pathways & Interactions for IGHV4OR15-8 Gene

SuperPathways for IGHV4OR15-8 Gene

No Data Available

Interacting Proteins for IGHV4OR15-8 Gene

Gene Ontology (GO) - Biological Process for IGHV4OR15-8 Gene


No data available for Pathways by source and SIGNOR curated interactions for IGHV4OR15-8 Gene

Drugs & Compounds for IGHV4OR15-8 Gene

No Compound Related Data Available

Transcripts for IGHV4OR15-8 Gene

mRNA/cDNA for IGHV4OR15-8 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV4OR15-8 Gene

No ASD Table

Relevant External Links for IGHV4OR15-8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV4OR15-8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGHV4OR15-8 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV4OR15-8 Gene

This gene is overexpressed in Spleen (x19.6), Whole Blood (x8.5), and Colon - Transverse (x5.1).

Protein differential expression in normal tissues from HIPED for IGHV4OR15-8 Gene

This gene is overexpressed in Stomach (16.6), Uterus (15.4), and Prostate (8.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for IGHV4OR15-8 Gene

genes like me logo Genes that share expression patterns with IGHV4OR15-8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGHV4OR15-8 Gene

Orthologs for IGHV4OR15-8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV4OR15-8 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 34
  • 53 (a)
Species where no ortholog for IGHV4OR15-8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV4OR15-8 Gene

Gene Tree for IGHV4OR15-8 (if available)
Gene Tree for IGHV4OR15-8 (if available)

Paralogs for IGHV4OR15-8 Gene

Variants for IGHV4OR15-8 Gene

Additional Variant Information for IGHV4OR15-8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV4OR15-8 Gene

Disorders for IGHV4OR15-8 Gene

No disorders were found for IGHV4OR15-8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGHV4OR15-8 Gene

Publications for IGHV4OR15-8 Gene

  1. Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2. (PMID: 7951227) Tomlinson IM … Winter G (Human molecular genetics 1994) 2 3 58
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 58

Products for IGHV4OR15-8 Gene

Sources for IGHV4OR15-8 Gene

Loading form....