Aliases for IGFBP6 Gene
External Ids for IGFBP6 Gene
Previous GeneCards Identifiers for IGFBP6 Gene
GeneCards Summary for IGFBP6 Gene
IGFBP6 (Insulin Like Growth Factor Binding Protein 6) is a Protein Coding gene. Diseases associated with IGFBP6 include Acth-Secreting Pituitary Adenoma and Exfoliative Ichthyosis. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include insulin-like growth factor binding and insulin-like growth factor II binding. An important paralog of this gene is IGFBP3.
UniProtKB/Swiss-Prot for IGFBP6 Gene
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.