Aliases for IGFBP1 Gene
Aliases for IGFBP1 Gene
- Insulin Like Growth Factor Binding Protein 1 2 3 5
- IGF-Binding Protein 1 2 3 4
- Placental Protein 12 2 3 4
- Alpha-Pregnancy-Associated Endometrial Globulin 2 3
- Growth Hormone Independent-Binding Protein 2 3
- Amniotic Fluid Binding Protein 2 3
- Binding Protein-28 2 3
- Binding Protein-26 2 3
- Binding Protein-25 2 3
- IGFBP-1 3 4
External Ids for IGFBP1 Gene
- HGNC: 5469
- Entrez Gene: 3484
- Ensembl: ENSG00000146678
- OMIM: 146730
- UniProtKB: P08833
Previous HGNC Symbols for IGFBP1 Gene
- IBP1
Previous GeneCards Identifiers for IGFBP1 Gene
- GC07P045574
- GC07P045668
- GC07P045701
- GC07P045894
- GC07P045816
- GC07P045927
- GC07P046043
- GC07P046067
- GC07P046097
- GC07P046128
- GC07P046158
Summaries for IGFBP1 Gene
-
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for IGFBP1 Gene
IGFBP1 (Insulin Like Growth Factor Binding Protein 1) is a Protein Coding gene. Diseases associated with IGFBP1 include Ovarian Disease and Mild Pre-Eclampsia. Among its related pathways are Photodynamic therapy-induced HIF-1 survival signaling and Metabolism of proteins. GO annotations related to this gene include insulin-like growth factor binding and insulin-like growth factor II binding. An important paralog of this gene is IGFBP2.
UniProtKB/Swiss-Prot for IGFBP1 Gene
-
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGFBP1 Gene
Genomics for IGFBP1 Gene
Regulatory Elements for IGFBP1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH07G045918 | 1.4 | Ensembl ENCODE dbSUPER | 10.9 | +33.4 | 33358 | 6.8 | SIN3A BMI1 RAD21 RFX5 GATA2 ZNF143 RCOR1 FOS DEK EGR2 | ENSG00000237471 TTC4P1 IGFBP1 RNU7-76P ENSG00000229628 IGFBP3 GC07P046243 |
| GH07G045888 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 5.2 | +1.0 | 955 | 2.4 | HNRNPUL1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 GATA2 | IGFBP1 GC07P046243 |
| GH07G045884 | 1.3 | ENCODE dbSUPER | 0.7 | -2.3 | -2292 | 3.2 | FOXA2 MLX ARID4B DMAP1 ZNF48 YY1 ZNF143 FOS SP5 ZHX2 | IGFBP1 ENSG00000283247 |
| GH07G045880 | 1.3 | ENCODE dbSUPER | 0.4 | -6.3 | -6286 | 3.0 | FOXA2 MLX ARID4B SIN3A DMAP1 YY1 FOS ZNF263 SP5 ZHX2 | SEPT7P2 ENSG00000283247 IGFBP1 |
| GH07G045874 | 1.2 | Ensembl ENCODE dbSUPER | 0.4 | -13.5 | -13527 | 1.4 | DRAP1 SAP130 JUN CHD7 ZNF48 RARA FOSL1 EGR1 GATA2 FOS | ENSG00000283247 IGFBP1 |
- Transcription factor binding sites by QIAGEN in the IGFBP1 gene promoter:
Regulatory Element Products
Genomic Location for IGFBP1 Gene
- Chromosome:
- 7
- Start:
- 45,888,357 bp from pter
- End:
- 45,893,668 bp from pter
- Size:
- 5,312 bases
- Orientation:
- Plus strand
Genomic View for IGFBP1 Gene
- Cytogenetic band:
-
- 7p12.3 by Ensembl
- 7p12.3 by Entrez Gene
- 7p12.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGFBP1 Gene
Proteins for IGFBP1 Gene
-
Protein details for IGFBP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P08833-IBP1_HUMAN
- Recommended name:
- Insulin-like growth factor-binding protein 1
- Protein Accession:
- P08833
- A4D2F4
- D3DVL9
- Q8IYP5
Protein attributes for IGFBP1 Gene
- Size:
- 259 amino acids
- Molecular mass:
- 27904 Da
- Quaternary structure:
-
- Binds equally well IGF1 and IGF2.
- SequenceCaution:
-
- Sequence=AAA52540.1; Type=Frameshift; Positions=55, 71; Evidence={ECO:0000305};
Protein Expression for IGFBP1 Gene
Post-translational modifications for IGFBP1 Gene
- Phosphorylated; probably by casein kinase II. Phosphorylation alters the affinity of the protein for IGFs. In amniotic fluid, the unmodified protein is the most abundant form, while mono-, bi-, tri- and tetraphosphorylated forms are present in decreasing amounts. The phosphorylation state may influence the propensity to proteolysis.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for IGFBP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for IGFBP1
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-
Cloud-Clone Corp. Antibodies for IGFBP1
- Invitrogen Antibodies for IGFBP1
- antibodies-online Antibodies for IGFBP1: See all 148
- GeneTex IGFBP1 antibody for IGFBP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for IGFBP1
Protein Products
- R&D Systems Proteins and Enzymes for IGFBP1 (IGFBP-1)
-
OriGene Purified Proteins for IGFBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for IGFBP1
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- Sino Biological Cell Lysates for IGFBP1
- Sino Biological Recombinant Proteins for IGFBP1
- ProSpec Recombinant Proteins for IGFBP1
-
Cloud-Clone Corp. Proteins for IGFBP1
- antibodies-online Proteins for IGFBP1: See all 51
- Search antibodies-online for peptides
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-
ProSci Proteins for IGFBP1
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for IGFBP1
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for IGFBP1 (IGFBP-1)
- antibodies-online Kits for IGFBP1: See all 99
-
Abcam assays for IGFBP1
No data available for DME Specific Peptides for IGFBP1 Gene
Domains & Families for IGFBP1 Gene
Gene Families for IGFBP1 Gene
Protein Domains for IGFBP1 Gene
Suggested Antigen Peptide Sequences for IGFBP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for IGFBP1 Gene
Function for IGFBP1 Gene
Molecular function for IGFBP1 Gene
- GENATLAS Biochemistry:
- insulin-like growth factor binding protein 1,high affinity,expressed in liver, decidua,kidney and in amniotic fluid,regulator of somatic growth and cellular proliferation,regulated by insulin and corticoids,duplicated in an atypical Silver Russel syndrome
- UniProtKB/Swiss-Prot Function:
- IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | TAS | 24431302 |
| GO:0005515 | protein binding | IPI | 26091039 |
| GO:0005520 | insulin-like growth factor binding | TAS,IEA | 2454104 |
| GO:0019838 | growth factor binding | IEA | -- |
| GO:0031994 | insulin-like growth factor I binding | IDA | 21550830 |
Phenotypes for IGFBP1 Gene
- MGI mutant phenotypes for IGFBP1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IGFBP1:
-
- Increased vaccinia virus (VACV) infection
- Decreased ionizing radiation sensitivity
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
Animal Models for IGFBP1 Gene
- MGI Knock Outs for IGFBP1:
-
- Igfbp1 tm1Taub
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for IGFBP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFBP1 gene
- Search ViGene Biosciences for IGFBP1
CRISPR Products
-
OriGene CRISPR knockouts for IGFBP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGFBP1
- GenScript: Design CRISPR guide RNA sequences for IGFBP1
miRNA for IGFBP1 Gene
- miRTarBase miRNAs that target IGFBP1
miRNA Products
- Search ViGene Biosciences for IGFBP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for IGFBP1
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Clone Products
-
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- Addgene plasmids for IGFBP1
- VectorBuilder custom plasmid, inducible vectors for IGFBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for IGFBP1
-
ViGene Biosciences adenoviral particle packaged cDNA for IGFBP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IGFBP1 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IGFBP1 Gene
Localization for IGFBP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IGFBP1 Gene
- Secreted.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | TAS,IBA | -- |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0005794 | Golgi apparatus | IDA | -- |
Pathways & Interactions for IGFBP1 Gene
Pathways by source for IGFBP1 Gene
1 Cell Signaling Technology pathway for IGFBP1 Gene
5 Reactome pathways for IGFBP1 Gene
1 GeneGo (Thomson Reuters) pathway for IGFBP1 Gene
Interacting Proteins for IGFBP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | TAS | 2454104 |
| GO:0007568 | aging | IEA | -- |
| GO:0008286 | insulin receptor signaling pathway | IEA | -- |
| GO:0030307 | positive regulation of cell growth | IEA | -- |
| GO:0036499 | PERK-mediated unfolded protein response | TAS | -- |
Transcripts for IGFBP1 Gene
mRNA/cDNA for IGFBP1 Gene
- (2) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (981) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for IGFBP1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for IGFBP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGFBP1
- GenScript: Design CRISPR guide RNA sequences for IGFBP1
miRNA Products
- Search ViGene Biosciences for IGFBP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for IGFBP1
- Browse OriGene Inhibitory RNA Products For IGFBP1
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFBP1 gene
Clone Products
-
OriGene ORF clones in human for IGFBP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for IGFBP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for IGFBP1
- VectorBuilder custom plasmid, inducible vectors for IGFBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for IGFBP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Mesothelial Cells Hepatic Mesenchyme
- Liver Lobule
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
-
Mesoderm (Gastrulation Derivatives)
- Mesothelial Cells Hepatic Mesenchyme
- Kidney (Urinary System)
- NULL (Integumentary System)
- Uncategorized
-
Uterus (Reproductive System)
-
Placenta (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for IGFBP1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IGFBP1 Gene
NURSA nuclear receptor signaling pathways regulating expression of IGFBP1 Gene:
IGFBP1SOURCE GeneReport for Unigene cluster for IGFBP1 Gene:
Hs.642938Evidence on tissue expression from TISSUES for IGFBP1 Gene
- Liver(4.8)
- Skin(4.3)
- Blood(2.4)
- Kidney(2.1)
- Nervous system(2.1)
Primer Products
-
OriGene qPCR primer pairs for IGFBP1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGFBP1 Gene
Orthologs for IGFBP1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IGFBP1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | IGFBP1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Igfbp1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Igfbp1 34 |
|
||
| dog (Canis familiaris) |
Mammalia | IGFBP1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | IGFBP1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | IGFBP1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | IGFBP1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | IGFBP1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | igfbp1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | igfbp1b 34 35 |
|
||
| igfbp1a 35 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for IGFBP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for IGFBP1 Gene
(2) SIMAP similar genes for IGFBP1 Gene using alignment to 5 proteins:
Variants for IGFBP1 Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000938997 | -- | 45,888,508(+) | CCCAT(A/C)CAGCG | utr-variant-5-prime | |
| rs1001299186 | -- | 45,888,978(+) | GTCTG(A/G)CGCCT | reference, missense | |
| rs1001841276 | -- | 45,887,446(+) | GGAGG(A/C)CCAGG | upstream-variant-2KB | |
| rs1001934871 | -- | 45,886,994(+) | TCACG(-/TC)TGTCT | upstream-variant-2KB | |
| rs1002296260 | -- | 45,888,321(+) | AAACC(A/G)TTTAC | upstream-variant-2KB |
Relevant External Links for IGFBP1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for IGFBP1 Gene
Disorders for IGFBP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ovarian disease |
|
|
| mild pre-eclampsia |
|
|
| pancreatic cancer, childhood |
|
|
| insulin-like growth factor i |
|
|
| hyperinsulinism |
|
Relevant External Links for IGFBP1
No data available for UniProtKB/Swiss-Prot and Genatlas for IGFBP1 Gene
Publications for IGFBP1 Gene
- Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms. (PMID: 19765076) Dolcini L. … Galliano M. (FEBS J. 2009) 3 4 22 64
- Insulin-like growth factor-binding protein-1: serum levels, promoter polymorphism, and associations with components of the metabolic syndrome in short subjects born small for gestational age. (PMID: 19158202) van der Kaay D. … Hokken-Koelega A. (J. Clin. Endocrinol. Metab. 2009) 3 22 46 64
- Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101. (PMID: 7678248) Jones J.I. … Clemmons D.R. (J. Biol. Chem. 1993) 3 4 22 64
- Isolation and characterization of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1). (PMID: 2461294) Brinkman A. … Drop S.L.S. (EMBO J. 1988) 2 3 4 64
- A single kinase generates the majority of the secreted phosphoproteome. (PMID: 26091039) Tagliabracci V.S. … Dixon J.E. (Cell 2015) 3 4 64
Products for IGFBP1 Gene
- R&D Systems Antibodies for IGFBP1 (IGFBP-1)
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- Custom Antibody ServicesOriGene Antibodies for IGFBP1
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- GenScript: Design CRISPR guide RNA sequences for IGFBP1
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- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for IGFBP1
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- Novus Biologicals Antibodies for IGFBP1
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- ProSpec Recombinant Proteins for IGFBP1
- Cloud-Clone Corp. Antibodies for IGFBP1
- Cloud-Clone Corp. Proteins for IGFBP1
- Addgene plasmids for IGFBP1
- antibodies-online Antibodies for IGFBP1: See all 148
- antibodies-online Kits for IGFBP1: See all 99
- antibodies-online Proteins for IGFBP1: See all 51
- Search antibodies-online for peptides
- GeneTex IGFBP1 antibody for IGFBP1
- GeneTex Proteins for IGFBP1
- ViGene Biosciences adenoviral particle packaged cDNA for IGFBP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IGFBP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IGFBP1 gene
- Search ViGene Biosciences for IGFBP1
- Santa Cruz Biotechnology (SCBT) Antibodies for IGFBP1
- Search Santa Cruz Biotechnology (SCBT) for IGFBP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IGFBP1
- Search for IGFBP1 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for IGFBP1
- Horizon Cell Lines for IGFBP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGFBP1
- VectorBuilder custom plasmid, inducible vectors for IGFBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFBP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for IGFBP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
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- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
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- (86) GenomeRNAi
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- (89) MalaCards
- (90) Invitrogen
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- (92) Vector BioLabs
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- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
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- (104) Addgene
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- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
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- (113) Taconic Biosciences
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- (133) NCBI Bookshelf
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- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
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- (145) IID
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- (148) SNPedia
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- (150) St John's Lab
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- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
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