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Aliases for IGF2 Gene

Aliases for IGF2 Gene

  • Insulin Like Growth Factor 2 2 3 5
  • T3M-11-Derived Growth Factor 3 4
  • Preptin 2 3
  • IGF-II 3 4
  • Insulin-Like Growth Factor 2 (Somatomedin A) 3
  • Chromosome 11 Open Reading Frame 43 2
  • Insulin-Like Growth Factor Type 2 3
  • Insulin-Like Growth Factor II 3
  • Insulin-Like Growth Factor 2 2
  • Somatomedin-A 4
  • Somatomedin A 2
  • C11orf43 3
  • PP9974 3
  • GRDF 3

External Ids for IGF2 Gene

Previous HGNC Symbols for IGF2 Gene

  • C11orf43

Previous GeneCards Identifiers for IGF2 Gene

  • GC11P000574
  • GC11M002241
  • GC11M002112
  • GC11M002118
  • GC11M002110
  • GC11M002113
  • GC11M001942
  • GC11M002152

Summaries for IGF2 Gene

Entrez Gene Summary for IGF2 Gene

  • This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

CIViC summary for IGF2 Gene

GeneCards Summary for IGF2 Gene

IGF2 (Insulin Like Growth Factor 2) is a Protein Coding gene. Diseases associated with IGF2 include Growth Restriction, Severe, With Distinctive Facies and Silver-Russell Syndrome. Among its related pathways are ERK Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and insulin receptor binding. An important paralog of this gene is IGF1.

UniProtKB/Swiss-Prot for IGF2 Gene

  • The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464).

  • Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

Gene Wiki entry for IGF2 Gene

Additional gene information for IGF2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGF2 Gene

Genomics for IGF2 Gene

GeneHancer (GH) Regulatory Elements for IGF2 Gene

Promoters and enhancers for IGF2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J002139 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 656.8 +3.5 3464 13 ELF3 RB1 MZF1 BATF ZNF48 RAD21 ZEB1 ZNF335 GLIS2 SCRT2 IGF2 INS-IGF2 TSSC4 ENSG00000199550 CD81 LSP1 LOC100505570 KRTAP5-6 FAM99B KRTAP5-5
GH11J002131 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 650.4 +14.1 14077 8 ZSCAN4 ARID4B KLF17 DMAP1 ZNF48 RARA ZNF335 GLIS2 ZNF366 EGR2 GC11M002158 MIR483 IGF2 CARS GC11P002138 ENSG00000284779 INS-IGF2
GH11J002127 Promoter/Enhancer 1.2 EPDnew ENCODE 650.3 +21.0 20972 2.1 ARID4B ERF RAD21 ZNF48 TEAD3 ZFHX2 POLR2A NR2F6 ZSCAN29 CREM ENSG00000240801 IGF2 INS-IGF2 ENSG00000284779 GC11P002077
GH11J002132 Promoter 0.7 EPDnew 650.4 +18.8 18813 0.1 PAF1 POLR2A ENSG00000240801 IGF2 GC11M002158 ENSG00000284779 INS-IGF2
GH11J002130 Promoter 0.6 EPDnew 650.4 +19.0 19007 0.1 POLR2A ENSG00000240801 IGF2 GC11M002158 ENSG00000284779 INS-IGF2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IGF2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the IGF2 gene promoter:
  • p53
  • AP-1

Genomic Locations for IGF2 Gene

Genomic Locations for IGF2 Gene
chr11:2,129,112-2,149,603
(GRCh38/hg38)
Size:
20,492 bases
Orientation:
Minus strand
chr11:2,150,342-2,170,833
(GRCh37/hg19)
Size:
20,492 bases
Orientation:
Minus strand

Genomic View for IGF2 Gene

Genes around IGF2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGF2 Gene

Proteins for IGF2 Gene

  • Protein details for IGF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01344-IGF2_HUMAN
    Recommended name:
    Insulin-like growth factor II
    Protein Accession:
    P01344
    Secondary Accessions:
    • B3KX48
    • B7WP08
    • C9JAF2
    • E3UN45
    • P78449
    • Q14299
    • Q1WM26
    • Q9UC68
    • Q9UC69

    Protein attributes for IGF2 Gene

    Size:
    180 amino acids
    Molecular mass:
    20140 Da
    Quaternary structure:
    • Interacts with MYORG; this interaction is required for IGF2 secretion (By similarity). Interacts with integrins ITGAV:ITGB3 and ITGA6:ITGB4; integrin-binding is required for IGF2 signaling (PubMed:28873464).
    Miscellaneous:
    • The IGF2 locus is imprinted. Paternal inherited gene is expressed, while the maternal inherited gene is imprinted, hence silenced. Transcripts from 5 promoters P0, P1, P2, P3 and P4 code for the same protein but are differentially regulated in a developmental stage and tissue specificity.

    Three dimensional structures from OCA and Proteopedia for IGF2 Gene

    Alternative splice isoforms for IGF2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IGF2 Gene

Post-translational modifications for IGF2 Gene

  • O-glycosylated with core 1 or possibly core 8 glycans. Thr-96 is a minor glycosylation site compared to Thr-99.
  • Proteolytically processed by PCSK4, proIGF2 is cleaved at Arg-128 and Arg-92 to generate big-IGF2 and mature IGF2.
  • Glycosylation at Thr163, isoforms=2, 399, and Thr96
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • IGF2_HUMAN (760)

No data available for DME Specific Peptides for IGF2 Gene

Domains & Families for IGF2 Gene

Gene Families for IGF2 Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Plasma proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Graphical View of Domain Structure for InterPro Entry

P01344

UniProtKB/Swiss-Prot:

IGF2_HUMAN :
  • Belongs to the insulin family.
Family:
  • Belongs to the insulin family.
genes like me logo Genes that share domains with IGF2: view

Function for IGF2 Gene

Molecular function for IGF2 Gene

UniProtKB/Swiss-Prot Function:
The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464).
UniProtKB/Swiss-Prot Function:
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
GENATLAS Biochemistry:
insulin-like growth factor 220kDa,regulator of somatic growth and cellular proliferation,maternally imprinted (telomeric imprinting domain at 11p15,containing ASCL2,H19 and IGF2,silenced and hypermethylated in most Wilms tumor),since the preimplantation 8-cells stage embryos,onwards;biallelic expression and loss of imprinting in fetal brain,in Wilms tumor,Beckwith-Wiedemann syndrome,other tumors and acute myeloid leukemia

LifeMap Function Summary for IGF2 Gene

IGF2 as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells:

Phenotypes From GWAS Catalog for IGF2 Gene

Gene Ontology (GO) - Molecular Function for IGF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005158 insulin receptor binding IPI 12138094
GO:0005159 insulin-like growth factor receptor binding TAS,IMP 2967174
GO:0005178 integrin binding IDA 28873464
GO:0005179 hormone activity IEA --
GO:0005515 protein binding IPI 10611375
genes like me logo Genes that share ontologies with IGF2: view
genes like me logo Genes that share phenotypes with IGF2: view

Human Phenotype Ontology for IGF2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for IGF2 Gene

MGI Knock Outs for IGF2:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IGF2

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for IGF2 Gene

Localization for IGF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for IGF2 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IGF2 gene
Compartment Confidence
plasma membrane 5
extracellular 5
cytoskeleton 3
nucleus 3
mitochondrion 2
peroxisome 2
endoplasmic reticulum 2
cytosol 2
lysosome 2
golgi apparatus 2
endosome 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for IGF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IEA --
GO:0005737 COLOCALIZES_WITH cytoplasm IBA --
GO:0005886 plasma membrane TAS --
GO:0031093 platelet alpha granule lumen TAS --
genes like me logo Genes that share ontologies with IGF2: view

Pathways & Interactions for IGF2 Gene

genes like me logo Genes that share pathways with IGF2: view

SIGNOR curated interactions for IGF2 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for IGF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II ISS --
GO:0000187 activation of MAPK activity IBA --
GO:0001501 skeletal system development TAS 8298652
GO:0001503 ossification IEA --
GO:0001649 osteoblast differentiation IEA --
genes like me logo Genes that share ontologies with IGF2: view

Drugs & Compounds for IGF2 Gene

(82) Drugs for IGF2 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(52) Additional Compounds for IGF2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with IGF2: view

Transcripts for IGF2 Gene

Unigene Clusters for IGF2 Gene

Insulin-like growth factor 2 (somatomedin A):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IGF2

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGF2 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - - -
SP2: -
SP3: -
SP4: - -

Relevant External Links for IGF2 Gene

GeneLoc Exon Structure for
IGF2
ECgene alternative splicing isoforms for
IGF2

Expression for IGF2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGF2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for IGF2 Gene

This gene is overexpressed in Amniocyte (28.1), Plasma (8.1), and Cerebrospinal fluid (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IGF2 Gene



NURSA nuclear receptor signaling pathways regulating expression of IGF2 Gene:

IGF2

SOURCE GeneReport for Unigene cluster for IGF2 Gene:

Hs.272259

mRNA Expression by UniProt/SwissProt for IGF2 Gene:

P01344-IGF2_HUMAN
Tissue specificity: Expressed in heart, placenta, lung, liver, muscle, kidney, tongue, limb, eye and pancreas.

Evidence on tissue expression from TISSUES for IGF2 Gene

  • Liver(5)
  • Pancreas(5)
  • Nervous system(5)
  • Muscle(4.9)
  • Kidney(4.5)
  • Intestine(4.4)
  • Lung(4)
  • Spleen(3.8)
  • Heart(3.7)
  • Blood(3.3)
  • Eye(3)
  • Adrenal gland(2.9)
  • Bone(2.7)
  • Thyroid gland(2.7)
  • Skin(2.3)

Phenotype-based relationships between genes and organs from Gene ORGANizer for IGF2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cheek
  • chin
  • ear
  • face
  • forehead
  • head
  • jaw
  • mandible
  • maxilla
  • meninges
  • mouth
  • neck
  • outer ear
  • skull
  • tooth
Thorax:
  • chest wall
  • clavicle
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • kidney
Pelvis:
  • pelvis
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • skin
  • spinal column
  • spinal cord
  • vertebrae
genes like me logo Genes that share expression patterns with IGF2: view

No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for IGF2 Gene

Orthologs for IGF2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGF2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia IGF2 34 33
  • 91.16 (n)
OneToOne
cow
(Bos Taurus)
Mammalia IGF2 34 33
  • 86.52 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Igf2 16 34 33
  • 86.02 (n)
rat
(Rattus norvegicus)
Mammalia Igf2 33
  • 85.84 (n)
chimpanzee
(Pan troglodytes)
Mammalia IGF2 34 33
  • 85.67 (n)
OneToOne
chicken
(Gallus gallus)
Aves IGF2 34 33
  • 64.86 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IGF2 34
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia igf2 33
  • 61.18 (n)
Str.10551 33
zebrafish
(Danio rerio)
Actinopterygii igf2b 34 33
  • 59.57 (n)
OneToMany
igf2a 34
  • 39 (a)
OneToMany
Dr.9288 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11849 33
Species where no ortholog for IGF2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGF2 Gene

ENSEMBL:
Gene Tree for IGF2 (if available)
TreeFam:
Gene Tree for IGF2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for IGF2: view image

Paralogs for IGF2 Gene

Paralogs for IGF2 Gene

(2) SIMAP similar genes for IGF2 Gene using alignment to 3 proteins:

  • IGF2_HUMAN
  • B2MUX6_HUMAN
  • E3UN46_HUMAN
genes like me logo Genes that share paralogs with IGF2: view

Variants for IGF2 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for IGF2 Gene

IGF2_HUMAN-P01344
Genetic variations in IGF2 are associated with body mass index (BMI). The BMI is a statistical measurement which compares a persons weight and height.

Sequence variations from dbSNP and Humsavar for IGF2 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1064794050 pathogenic, not provided, Russell-Silver syndrome 2,135,446(-) G/C coding_sequence_variant, stop_gained
rs869320620 pathogenic, Growth restriction, severe, with distinctive facies 2,135,501(-) G/A/T coding_sequence_variant, missense_variant, stop_gained
rs553443857 pathogenic, not provided 2,135,425(-) G/A/T coding_sequence_variant, stop_gained, synonymous_variant
rs1057518115 likely-pathogenic, not provided 2,135,427(-) A/G coding_sequence_variant, missense_variant
rs755455183 uncertain-significance, not specified 2,133,012(-) GGGGGGG/GGGGGGGG coding_sequence_variant, frameshift

Structural Variations from Database of Genomic Variants (DGV) for IGF2 Gene

Variant ID Type Subtype PubMed ID
nsv951284 CNV deletion 24416366
nsv825707 CNV gain 20364138
nsv553069 CNV loss 21841781
nsv553068 CNV loss 21841781
nsv553047 CNV gain 21841781
nsv467645 CNV gain 19166990
nsv1118203 CNV deletion 24896259
nsv1070426 CNV deletion 25765185
esv2673506 CNV deletion 23128226
dgv551e59 CNV duplication 20981092

Variation tolerance for IGF2 Gene

Residual Variation Intolerance Score: 34.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.27; 52.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for IGF2 Gene

Human Gene Mutation Database (HGMD)
IGF2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGF2

SNP Genotyping and Copy Number Assay Products

Disorders for IGF2 Gene

MalaCards: The human disease database

(90) MalaCards diseases for IGF2 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

UniProtKB/Swiss-Prot

IGF2_HUMAN
  • Silver-Russell syndrome (SRS) [MIM:180860]: A clinically heterogeneous condition characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations. The phenotypic expression changes during childhood and adolescence, with the facial features and asymmetry usually becoming more subtle with age. {ECO:0000269 PubMed:19066168}. Note=The gene represented in this entry is involved in disease pathogenesis. Most of the cases of Silver-Russell syndrome are caused by the epigenetic changes of DNA hypomethylation at the telomeric imprinting control region (ICR1) on chromosome 11p15, involving the H19 and IGF2 genes.
  • Growth restriction, severe, with distinctive facies (GRDF) [MIM:616489]: A disease characterized by severe prenatal and postnatal growth restriction, facial dysmorphism, and short stature in the presence of normal or slightly elevated growth hormone levels. {ECO:0000269 PubMed:26154720}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for IGF2 Gene

hypoglycemia,tumor induced,putative susceptibility factor for obesity in association with INS in British population

Additional Disease Information for IGF2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with IGF2: view

Publications for IGF2 Gene

  1. Parent-of-origin specific linkage and association of the IGF2 gene region with birth weight and adult metabolic risk factors. (PMID: 19546867) Souren NY … Zeegers MP (International journal of obesity (2005) 2009) 3 22 44 58
  2. [Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]. (PMID: 19421925) Knebel B … Kotzka J (Deutsche medizinische Wochenschrift (1946) 2009) 3 22 44 58
  3. Association of gastric cancer with tyrosine hydroxylase gene polymorphism in a northwestern Chinese population. (PMID: 17972051) Li ZQ … Wang XL (Clinical and experimental medicine 2007) 3 22 44 58
  4. Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women. (PMID: 17488802) Heude B … Sandhu MS (The Journal of clinical endocrinology and metabolism 2007) 3 22 44 58
  5. Anorexia nervosa, perfectionism, and dopamine D4 receptor (DRD4). (PMID: 17440932) Bachner-Melman R … Ebstein RP (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007) 3 22 44 58

Products for IGF2 Gene

Sources for IGF2 Gene

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