Aliases for IGBP1 Gene
External Ids for IGBP1 Gene
Previous HGNC Symbols for IGBP1 Gene
Previous GeneCards Identifiers for IGBP1 Gene
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. [provided by RefSeq, Jul 2008]
GeneCards Summary for IGBP1 Gene
IGBP1 (Immunoglobulin Binding Protein 1) is a Protein Coding gene. Diseases associated with IGBP1 include Corpus Callosum, Agenesis Of, With Mental Retardation, Ocular Coloboma, And Micrognathia and Opitz-Gbbb Syndrome. Among its related pathways are Macroautophagy and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include protein domain specific binding and protein phosphatase 2A binding. An important paralog of this gene is IGBP1P2.
UniProtKB/Swiss-Prot Summary for IGBP1 Gene
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.