Aliases for IFRD1 Gene
External Ids for IFRD1 Gene
Previous GeneCards Identifiers for IFRD1 Gene
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
GeneCards Summary for IFRD1 Gene
IFRD1 (Interferon Related Developmental Regulator 1) is a Protein Coding gene. Diseases associated with IFRD1 include Spinocerebellar Ataxia 18 and Lung Disease. Among its related pathways are Hypertrophy Model. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is ENSG00000288640.
UniProtKB/Swiss-Prot Summary for IFRD1 Gene
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).