Aliases for IFNA21 Gene
External Ids for IFNA21 Gene
Previous GeneCards Identifiers for IFNA21 Gene
This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]
GeneCards Summary for IFNA21 Gene
IFNA21 (Interferon Alpha 21) is a Protein Coding gene. Diseases associated with IFNA21 include Rubella and Melanoma, Cutaneous Malignant 1. Among its related pathways are all-trans-Retinoic Acid Mediated Apoptosis and Tuberculosis. Gene Ontology (GO) annotations related to this gene include cytokine activity and type I interferon receptor binding. An important paralog of this gene is IFNA4.
UniProtKB/Swiss-Prot Summary for IFNA21 Gene
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.