Aliases for IFITM5 Gene
External Ids for IFITM5 Gene
Previous GeneCards Identifiers for IFITM5 Gene
This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012]
GeneCards Summary for IFITM5 Gene
IFITM5 (Interferon Induced Transmembrane Protein 5) is a Protein Coding gene. Diseases associated with IFITM5 include Osteogenesis Imperfecta, Type V and Osteogenesis Imperfecta, Type Vi. An important paralog of this gene is IFITM2.
UniProtKB/Swiss-Prot Summary for IFITM5 Gene
Required for normal bone mineralization.